Search Results - "Hance, Allan"

HIV Drug Resistance by Clavel, François, Hance, Allan J

“…Combinations of antiretroviral drugs have proven remarkably effective in controlling the progression of HIV disease and prolonging survival, but these benefits…”
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Gag mutations strongly contribute to HIV-1 resistance to protease inhibitors in highly drug-experienced patients besides compensating for fitness loss by Dam, Elisabeth, Quercia, Romina, Glass, Bärbel, Descamps, Diane, Launay, Odile, Duval, Xavier, Kräusslich, Hans-Georg, Hance, Allan J, Clavel, François

“…Human immunodeficiency virus type 1 (HIV-1) resistance to protease inhibitors (PI) results from mutations in the viral protease (PR) that reduce PI binding but…”
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Hypermutation of HIV-1 DNA in the Absence of the Vif Protein by Lecossier, Denise, Bouchonnet, Francine, Clavel, François, Hance, Allan J.

“…The Vif (viral infectivity factor) protein of HIV-1 is essential for the production of infectious virus by T lymphocytes and macrophages, the natural targets…”
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Contribution of Recombination to the Evolution of Human Immunodeficiency Viruses Expressing Resistance to Antiretroviral Treatment by NORA, Tamara, CHARPENTIER, Charlotte, TENAILLON, Olivier, HOEDE, Claire, CLAVEL, Frangois, HANCE, Allan J

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Kinetics of the establishment of HIV-1 viral interference and comprehensive analysis of the contribution of viral genes by Remion, Azaria, Delord, Marc, Hance, Allan J, Saragosti, Sentob, Mammano, Fabrizio

“…Abstract Viral interference defines the reduced susceptibility of an infected cell to reinfection. For HIV-1, both receptor-dependent and independent pathways…”
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Gag Cytotoxic T Lymphocyte Escape Mutations Can Increase Sensitivity of HIV-1 to Human TRIM5α, Linking Intrinsic and Acquired Immunity by BATTIVELLI, Emilie, MIGRAINE, Julie, LECOSSIER, Denise, YENI, Patrick, CLAVEL, François, HANCE, Allan J

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Modulation of TRIM5α Activity in Human Cells by Alternatively Spliced TRIM5 Isoforms by BATTIVELLI, Emilie, MIGRAINE, Julie, LECOSSIER, Denise, MATSUOKA, Saori, PEREZ-BERCOFF, Danielle, SARAGOSTI, Sentob, CLAVEL, François, HANCE, Allan J

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CIB1 and CIB2 are HIV-1 helper factors involved in viral entry by Godinho-Santos, Ana, Hance, Allan J., Gonçalves, João, Mammano, Fabrizio

“…HIV-1 relies on the host-cell machinery to accomplish its replication cycle, and characterization of these helper factors contributes to a better understanding…”
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Genetically Intact but Functionally Impaired HIV-1 Env Glycoproteins in the T-Cell Reservoir by de Verneuil, Anne, Migraine, Julie, Mammano, Fabrizio, Molina, Jean-Michel, Gallien, Sébastien, Mouquet, Hugo, Hance, Allan J, Clavel, François, Dutrieux, Jacques

“…HIV-infected subjects under antiretroviral treatment (ART) harbor a persistent viral reservoir in resting CD4 T cells, which accounts for the resurgence of HIV…”
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Single-dose pharmacokinetics and pharmacodynamics of oral tenofovir and emtricitabine in blood, saliva and rectal tissue: a sub-study of the ANRS IPERGAY trial by Fonsart, Julien, Saragosti, Sentob, Taouk, Milad, Peytavin, Gilles, Bushman, Lane, Charreau, Isabelle, Hance, Allan, Goldwirt, Lauriane, Morel, Stéphane, Mammano, Fabrizio, Loze, Bénédicte, Capitant, Catherine, Clavel, François, Mahjoub, Nadia, Meyer, Laurence, Anderson, Peter L, Delaugerre, Constance, Molina, Jean-Michel

“…In the ANRS IPERGAY pre-exposure prophylaxis (PrEP) trial, a single dose of tenofovir disoproxil fumarate and emtricitabine was taken orally 2-24 h before…”
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Delaying reverse transcription does not increase sensitivity of HIV-1 to human TRIM5α by Battivelli, Emilie, Lecossier, Denise, Clavel, François, Hance, Allan J

“…Because uncoating of the capsid is linked to reverse transcription, modifications that delay this process lead to the persistence in the cytoplasm of capsids…”
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Genotypic and Phenotypic Diversity of the Replication-Competent HIV Reservoir in Treated Patients by Nicolas, Alexandre, Migraine, Julie, Dutrieux, Jacques, Salmona, Maud, Tauzin, Alexandra, Hachiya, Atsuko, Estaquier, Jérôme, Molina, Jean-Michel, Clavel, François, Hance, Allan J., Mammano, Fabrizio

“…In HIV infection, viral rebound after treatment discontinuation is considered to originate predominantly from viral genomes integrated in resting CD4+ T…”
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Pressure from TRIM5α Contributes to Control of HIV-1 Replication by Individuals Expressing Protective HLA-B Alleles by Granier, Clémence, Battivelli, Emilie, Lécuroux, Camille, Venet, Alain, Lambotte, Olivier, Schmitt-Boulanger, Marion, Delaugerre, Constance, Molina, Jean-Michel, Chakrabarti, Lisa A, Clavel, François, Hance, Allan J

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Strain-Specific Differences in the Impact of Human TRIM5α, Different TRIM5α Alleles, and the Inhibition of Capsid-Cyclophilin A Interactions on the Infectivity of HIV-1 by BATTIVELLI, Emilie, LECOSSIER, Denise, MATSUOKA, Saori, MIGRAINE, Julie, CLAVEL, François, HANCE, Allan J

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Modulation of HIV-1 infectivity and cyclophilin A-dependence by Gag sequence and target cell type by Matsuoka, Saori, Dam, Elisabeth, Lecossier, Denise, Clavel, François, Hance, Allan J

“…HIV-1 Gag proteins are essential for virion assembly and viral replication in newly infected cells. Gag proteins are also strong determinants of viral…”
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Extensive Recombination among Human Immunodeficiency Virus Type 1 Quasispecies Makes an Important Contribution to Viral Diversity in Individual Patients by CHARPENTIER, Charlotte, NORA, Tamara, TENAILLON, Olivier, CLAVEL, Frangois, HANCE, Allan J

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Role of Minority Populations of Human Immunodeficiency Virus Type 1 in the Evolution of Viral Resistance to Protease Inhibitors by CHARPENTIER, Charlotte, DMYER, Dominic E, MAMMANO, Fabrizio, LECOSSIER, Denise, CLAVEL, Francois, HANCE, Allan J

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Role of the Envelope Genetic Context in the Development of Enfuvirtide Resistance in Human Immunodeficiency Virus Type 1-Infected Patients by LABROSSE, Béatrice, MORAND-JOUBERT, Laurence, GOUBARD, Armelle, ROCHAS, Séverine, LABERNARDIERE, Jean-Louis, PACANOWSKI, Jerome, MEYNARD, Jean-Luc, HANCE, Allan J, CLAVEL, Francois, MAMMANO, Fabrizio

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APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses by Heidmann, Thierry, Schwartz, Olivier, Esnault, Cécile, Heidmann, Odile, Delebecque, Frédéric, Dewannieux, Marie, Ribet, David, Hance, Allan J

“…Endogenous retroviruses are multicopy retroelements accounting for nearly 10% of murine or human genomes. These retroelements spread into our ancestral genome…”
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Three-Dimensional Characterization of Pathologic Lesions in Pulmonary Langerhans Cell Histiocytosis by Kambouchner, Marianne, Basset, Francoise, Marchal, Joelle, Uhl, Jean Francois, Hance, Allan J, Soler, Paul

“…The characteristic lesions of pulmonary Langerhans cell histiocytosis (LCH) associate destructive granulomas containing large numbers of Langerhans cells and…”
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