Search Results - "Hanawa, Takehisa"

Adsorption of a poorly water-soluble drug onto porous calcium silicate by the sealed heating method by Kawano, Yayoi, Chen, Shiyang, Hanawa, Takehisa

“…[Display omitted] •IBU crystals could be adsorbed and amorphized in porous calcium silicate (FRL) by heating in a sealed container.•The porous surface feature…”
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Saturated adsorption of lidocaine and coal tar dyes onto porous polytetrafluoroethylene by Mitsuya, Kengo, Goto, Satoru, Otsuka, Yuta, Kawano, Yayoi, Hanawa, Takehisa

“…Polytetrafluoroethylene (PTFE) has excellent physical properties and has been used in a wide range of applications in various fields. Adsorption research on…”
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Wound Healing Promotion by Hyaluronic Acid: Effect of Molecular Weight on Gene Expression and In Vivo Wound Closure by Kawano, Yayoi, Patrulea, Viorica, Sublet, Emmanuelle, Borchard, Gerrit, Iyoda, Takuya, Kageyama, Rihoko, Morita, Asa, Seino, Satoshi, Yoshida, Hideto, Jordan, Olivier, Hanawa, Takehisa

“…Hyaluronic acid (HA) has been known to play an important role in wound healing process. However, the effect of molecular weight (MW) of exogenously…”
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Feasibility study on the application of pectin as pollen adsorbent to prevent pollinosis by Ozawa, Chihiro, Iwami, Chika, Kawano, Yayoi, Hanawa, Takehisa

“…In this study, to investigate the feasibility of applying pectin as an adsorbent to prevent pollinosis, we focused on the two types, low- and high‑methoxy…”
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Synergistic Antinociceptive Activity of Tramadol/Acetaminophen Combination Mediated by μ-Opioid Receptors by Yoshizawa, Kazumi, Arai, Narumaki, Suzuki, Yukina, Fujita, Ayumi, Takahashi, Yukino, Kawano, Yayoi, Hanawa, Takehisa

“…We investigated whether tramadol could suppress both neuropathic and inflammatory pain in mice at the same dose level. We also examined the effects of drugs…”
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A novel hydrogel sheet prevents postoperative pancreatic fistula in a rat model by Kemmochi, Akira, Tamura, Takafumi, Shimizu, Yoshio, Owada, Yohei, Ozawa, Yusuke, Hisakura, Katsuji, Oda, Tatsuya, Kawano, Yayoi, Hanawa, Takehisa, Ohkohchi, Nobuhiro

“…Aim To evaluate the efficacy of a novel hydrogel sheet in preventing postoperative pancreatic fistula (POPF). Background Postoperative pancreatic fistula is a…”
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Enhancing the Solubility of Curcumin Using a Solid Dispersion System with Hydroxypropyl-β-Cyclodextrin Prepared by Grinding, Freeze-Drying, and Common Solvent Evaporation Methods by Mai, Nguyen Ngoc Sao, Nakai, Riko, Kawano, Yayoi, Hanawa, Takehisa

“…Cyclodextrins (CDs) and their derivatives significantly increase drug solubility by forming drug/CD complexes known as solid dispersions (SDs), which consist…”
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Solubility Enhancement of Ibuprofen by Adsorption onto Spherical Porous Calcium Silicate by Kawano, Yayoi, Chen, Shiyang, Hanawa, Takehisa

“…The solubility of a drug is higher when it is in an amorphous form than when it is in a crystalline form. To enhance the solubility of ibuprofen (IBU), a…”
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Preparation and Evaluation of a Powdered Rebamipide Mouthwash as In-Hospital Formulation: Considering Dispersion before Use in Patients by Ishii, Naoko, Mizobuchi, Senri, Kawano, Yayoi, Hanawa, Takehisa

“…In Japan, rebamipide (RB) mouthwash (RB-MW) for oral mucositis induced by cancer chemotherapy has been prepared using in-hospital formulation. Usually, RB-MW…”
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Evaluation of nephrotoxicity and ototoxicity following amikacin administration once daily or every 48 hours in neonates by Endo, Aiju, Hanawa, Kazumi, Nemoto, Atsushi, Ishikawa, Takahiro, Kazama, Shizuka, Kagami, Yu, Maebayashi, Yuki, Katsumata, Nobuyuki, Naito, Atsushi, Kobayashi, Yoshifumi, Kawano, Yayoi, Hanawa, Takehisa

“…The purpose of this study was to evaluate the effects of once daily (OD) or every 48 hours (every-48-h) administration of amikacin (AMK) on renal function and…”
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Development of Hospital Formulations Based on Medical Need by Kawano, Yayoi, Hanawa, Takehisa

“…Aphthous stomatitis is induced by chemotherapy and radiotherapy. It has been reported that 100% of patients administered high-dose chemotherapy and 80% of…”
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Testing a Benchtop Wet-Milling Method for Preparing Nanoparticles and Suspensions as Hospital Formulations by Kawano, Yayoi, Shimizu, Yuichiro, Hanawa, Takehisa

“…In clinical practice, for elderly or pediatric patients who have difficulty swallowing, solid dosage forms such as tablets or capsules are crushed or unsealed,…”
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Development and Characterization of Oral Spray for Stomatitis Containing Irsogladine Maleate by Kawano, Yayoi, Imamura, Ayano, Nakamura, Tomoe, Akaishi, Mio, Satoh, Mitsutoshi, Hanawa, Takehisa

“…The stomatitis caused by anticancer agents and radiation therapy deteriorates patient QOL, potentially causing eating disorders as a result of pain. Although…”
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(S)-1-(4-Dimethylaminophenylcarbonyl)-3-aminopyrrolidine: A derivatization reagent for enantiomeric separation and sensitive detection of chiral carboxylic acids by LC/ESI-MS/MS by Ogawa, Shoujiro, Tadokoro, Hiroaki, Sato, Maho, Hanawa, Takehisa, Higashi, Tatsuya

“…•A novel derivatization reagent, 1-DAPAP, was developed for chiral carboxylic acids.•Based on the derivatization, the ESI-MS/MS response was increased by…”
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Index for the appropriate vancomycin dosing in premature neonates and infants by Endo, Aiju, Nemoto, Atsushi, Hanawa, Kazumi, Ishikawa, Takahiro, Koshiishi, Mai, Maebayashi, Yuki, Hasebe, Yohei, Naito, Atsushi, Kobayashi, Yoshifumi, Isobe, Katsuhiko, Kawano, Yayoi, Hanawa, Takehisa

“…Background In neonates, vancomycin (VCM) is used to treat Gram‐positive bacterial infections. However, VCM blood concentrations are affected by gestational…”
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Microparticulated Mefenamic Acid with High Dispersion Stability for Pediatric Dosage Form by Yamazaki, Moe, Shimamura, Emi, Hanawa, Takehisa, Kawano, Yayoi

“…Mefenamic acid (MFA), a water-insoluble drug, is used as a suspension in the medical field, but it requires shaking before using to disperse MFA content in the…”
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Preparation and Evaluation of Stomatitis Film Using Xyloglucan Containing Loperamide by Kawano, Yayoi, Sasatsu, Masanaho, Mizutani, Ayako, Hirose, Kaoru, Hanawa, Takehisa, Onishi, Hiraku

“…Stomatitis induced by radiation therapy or cancer chemotherapy is a factor in sleep disorders and/or eating disorders, markedly decreasing patient quality of…”
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Targeting miR‐223 in neutrophils enhances the clearance of Staphylococcus aureus in infected wounds by de Kerckhove, Maiko, Tanaka, Katsuya, Umehara, Takahiro, Okamoto, Momoko, Kanematsu, Sotaro, Hayashi, Hiroko, Yano, Hiroki, Nishiura, Soushi, Tooyama, Shiho, Matsubayashi, Yutaka, Komatsu, Toshimitsu, Park, Seongjoon, Okada, Yuka, Takahashi, Rina, Kawano, Yayoi, Hanawa, Takehisa, Iwasaki, Keisuke, Nozaki, Tadashige, Torigoe, Hidetaka, Ikematsu, Kazuya, Suzuki, Yutaka, Tanaka, Katsumi, Martin, Paul, Shimokawa, Isao, Mori, Ryoichi

“…Argonaute 2 bound mature microRNA (Ago2‐miRNA) complexes are key regulators of the wound inflammatory response and function in the translational processing of…”
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Effect of Polymers and Storage Relative Humidity on Amorphous Rebamipide and Its Solid Dispersion Transformation: Multiple Spectra Chemometrics of Powder X-Ray Diffraction and Near-Infrared Spectroscopy by Otsuka, Yuta, Utsunomiya, Yuiko, Umeda, Daiki, Yonemochi, Etsuo, Kawano, Yayoi, Hanawa, Takehisa

“…This study aimed to investigate the effect of polymers and storage relative humidity on amorphous rebamipide (RB) and its solid dispersion phase transformation…”
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Effects of polymer molecular weight on curcumin amorphous solid dispersion; at-line monitoring system based on attenuated total reflectance mid-infrared and near-infrared spectroscopy by Mai, Nguyen Ngoc Sao, Otsuka, Yuta, Goto, Satoru, Kawano, Yayoi, Hanawa, Takehisa

“…The aim of this study was to investigate the effects of the molecular weight (Mw) of hydroxypropyl cellulose (HPC) and grinding duration on solid dispersions…”
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