Search Results - "Hanakawa, Y"

A sporadic case of granulomatous disease negative for NOD2 mutations and mimicking Blau syndrome by Oda, F., Murakami, M., Hanakawa, Y., Tohyama, M., Nakano, N., Nishikomori, R., Kambe, N., Sayama, K.

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Pre-B-cell leukemia transcription factor 1 is a major target of promyelocytic leukemia zinc-finger-mediated melanoma cell growth suppression by SHIRAISHI, K, YAMASAKI, K, NANBA, D, INOUE, H, HANAKAWA, Y, SHIRAKATA, Y, HASHIMOTO, K, HIGASHIYAMA, S

“…Promyelocytic leukemia zinc-finger (PLZF) is a transcriptional repressor and tumor suppressor. PLZF is expressed in melanocytes but not in melanoma cells, and…”
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Desmosomes and disease: pemphigus and bullous impetigo by Payne, Aimee S, Hanakawa, Yasushi, Amagai, Masayuki, Stanley, John R

“…Desmosomal cadherins are the pathophysiologic targets of autoimmune or toxin-mediated disruption in the human diseases pemphigus and bullous impetigo…”
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CXCL16 is a novel mediator of the innate immunity of epidermal keratinocytes by Tohyama, Mikiko, Sayama, Koji, Komatsuzawa, Hitoshi, Hanakawa, Yasushi, Shirakata, Yuji, Dai, Xjuju, Yang, Lujun, Tokumaru, Sho, Nagai, Hiroshi, Hirakawa, Satoshi, Sugai, Motoyuki, Hashimoto, Koji

“…The epidermis is constantly exposed to a variety of microbial pathogens and plays a vital role in resisting them. Soluble CXC chemokine ligand (CXCL) 16, which…”
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Prostaglandins and activation of AC/cAMP prevents anoikis in IEC-18 by Joseph, R R, Yazer, E, Hanakawa, Y, Stadnyk, A W

“…Recent data indicates that chronic inflammation of the intestine such as Crohn's or ulcerative colitis puts those individuals at heightened risk for colorectal…”
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Lack of Mucosal Involvement in Pemphigus Foliaceus May be Due to Low Expression of Desmoglein 1 by Shirakata, Yuji, Amagai, Masayuki, Hanakawa, Yasushi, Nishikawa, Takeji, Hashimoto, Koji

“…Oral mucosal lesions are seen in most cases of pemphigus vulgaris, whereas they are only rarely seen in pemphigus foliaceus; however, both pemphigus vulgaris…”
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Mechanisms of Blister Formation by Staphylococcal Toxins by Hanakawa, Yasushi, Stanley, John R.

“…Many children suffer from the bacterial skin diseases bullous impetigo and staphylococcal scalded skin syndrome (SSSS). Staphylococcus aureus, which produces…”
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Cre-loxP adenovirus-mediated foreign gene expression in skin-equivalent keratinocytes by Hanakawa, Y., Shirakata, Y., Nagai, H., Yahata, Y., Tokumaru, S., Yamasaki, K., Tohyama, M., Sayama, K., Hashimoto, K.

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Food-dependent exercise-induced anaphylaxis: a case related to the amount of food allergen ingested by HANAKAWA, Y, TOHYAMA, M, SHIRAKATA, Y, MURAKAMI, S, HASHIMOTO, K

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Superantigen production by Staphylococcus aureus in psoriasis by Sayama, K, Midorikawa, K, Hanakawa, Y, Sugai, M, Hashimoto, K

“…Activation of T cells is believed to play a critical role in the pathogenesis of psoriasis. Recently, it has been proposed that psoriasis is a T-cell-mediated…”
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Induction of Keratinocyte Migration via Transactivation of the Epidermal Growth Factor Receptor by the Antimicrobial Peptide LL-37 by Tokumaru, Sho, Sayama, Koji, Shirakata, Yuji, Komatsuzawa, Hitoshi, Ouhara, Kazuhisa, Hanakawa, Yasushi, Yahata, Yoko, Dai, Xiuju, Tohyama, Mikiko, Nagai, Hiroshi, Yang, Lujun, Higashiyama, Shigeki, Yoshimura, Akihiko, Sugai, Motoyuki, Hashimoto, Koji

“…The closure of skin wounds is essential for resistance against microbial pathogens, and keratinocyte migration is an important step in skin wound healing…”
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Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display by Payne, Aimee S., Ishii, Ken, Kacir, Stephen, Lin, Chenyan, Li, Hong, Hanakawa, Yasushi, Tsunoda, Kazuyuki, Amagai, Masayuki, Stanley, John R., Siegel, Don L.

“…Pemphigus is a life-threatening blistering disorder of the skin and mucous membranes caused by pathogenic autoantibodies to desmosomal adhesion proteins…”
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Induction of the cytokine signal regulator SOCS3/CIS3 as a therapeutic strategy for treating inflammatory arthritis by Shouda, T, Yoshida, T, Hanada, T, Wakioka, T, Oishi, M, Miyoshi, K, Komiya, S, Kosai, K, Hanakawa, Y, Hashimoto, K, Nagata, K, Yoshimura, A

“…Immune and inflammatory systems are controlled by multiple cytokines, including ILs and INFs. These cytokines exert their biological functions through Janus…”
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Nuclear Translocation of Phosphorylated STAT3 Is Essential for Vascular Endothelial Growth Factor-induced Human Dermal Microvascular Endothelial Cell Migration and Tube Formation by Yahata, Yoko, Shirakata, Yuji, Tokumaru, Sho, Yamasaki, Kenshi, Sayama, Koji, Hanakawa, Yasushi, Detmar, Michael, Hashimoto, Koji

“…Vascular endothelial growth factor (VEGF) is a potent, multifunctional, endothelial-cell-specific growth factor. It stimulates proliferation and migration of…”
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Staphylococcal Exfoliative Toxin B Specifically Cleaves Desmoglein 1 by Amagai, Masayuki, Nishifuji, Koji, Yamaguchi, Takayuki, Hanakawa, Yasushi, Sugai, Motoyuki, Stanley, John R.

“…Staphylococcal scalded skin syndrome and its localized form, bullous impetigo, show superficial epidermal blister formation caused by exfoliative toxin A or B…”
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Suppression of Stat3 promotes neurogenesis in cultured neural stem cells by Gu, Feng, Hata, Ryuji, Ma, Yong-Jie, Tanaka, Junya, Mitsuda, Noriaki, Kumon, Yoshiaki, Hanakawa, Yasushi, Hashimoto, Koji, Nakajima, Koichi, Sakanaka, Masahiro

“…To investigate the effects of signal transducer and activator of transcription 3 (Stat3) on neural stem cell fate, stem cells were inoculated with an…”
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Downregulation of E-cadherin and Desmoglein 1 by autocrine hepatocyte growth factor during melanoma development by GANG LI, SCHAIDER, Helmut, SATYAMOORTHY, Kapaettu, HANAKAWA, Yasushi, HASHIMOTO, Koji, HERLYN, Meenhard

“…During melanoma development, transformed cells evade keratinocyte-mediated control by downregulating cell adhesion molecules. This study investigated the…”
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Ectodomain Shedding of Epidermal Growth Factor Receptor Ligands Is Required for Keratinocyte Migration in Cutaneous Wound Healing by Tokumaru, Sho, Higashiyama, Shigeki, Endo, Takeshi, Nakagawa, Takatoshi, Miyagawa, Jun-ichiro, Yamamori, Katsumi, Hanakawa, Yasushi, Ohmoto, Hiroshi, Yoshino, Kohichiro, Shirakata, Yuji, Matsuzawa, Yuji, Hashimoto, Koji, Taniguchi, Naoyuki

“…Keratinocyte proliferation and migration are essential to cutaneous wound healing and are, in part, mediated in an autocrine fashion by epidermal growth factor…”
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Inhibition of human kallikreins 5 and 7 by the serine protease inhibitor lympho-epithelial Kazal-type inhibitor (LEKTI) by Schechter, Norman M, Choi, Eun-Jung, Wang, Zhe-Mei, Hanakawa, Yasushi, Stanley, John R, Kang, Ya'an, Clayman, Gary L, Jayakumar, Arumugam

“…LEKTI is a 120-kDa protein that plays an important role in skin development, as mutations affecting LEKTI synthesis underlie Netherton syndrome, an inherited…”
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Suppressor of cytokine signaling-3 is a biomechanical stress-inducible gene that suppresses gp130-mediated cardiac myocyte hypertrophy and survival pathways by Yasukawa, H, Hoshijima, M, Gu, Y, Nakamura, T, Pradervand, S, Hanada, T, Hanakawa, Y, Yoshimura, A, Ross, Jr, J, Chien, K R

“…The gp130 cytokine receptor activates a cardiomyocyte survival pathway during the transition to heart failure following the biomechanical stress of pressure…”
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