Search Results - "Hanafy, Nemany A N"

Chitosan as a Natural Copolymer with Unique Properties for the Development of Hydrogels by Sami El-banna, Fatma, Mahfouz, Magdy Elsayed, Leporatti, Stefano, El-Kemary, Maged, A. N. Hanafy, Nemany

“…Hydrogel-based polymers are represented by those hydrophilic polymers having functional groups in their chain such as amine (NH2), hydroxyl [-OH], amide…”
Get full text

Simultaneous Administration of Bevacizumab with Bee-Pollen Extract-Loaded Hybrid Protein Hydrogel NPs Is a Promising Targeted Strategy against Cancer Cells by Hanafy, Nemany A N, Eltonouby, Eman Ali Bakr, Salim, Elsayed I, Mahfouz, Magdy E, Leporatti, Stefano, Hafez, Ezar H

“…Bevacizumab (Bev) a humanized monoclonal antibody that fights vascular endothelial growth factor A (VEGF-A). It was the first specifically considered…”
Get full text

Fighting Non-Small Lung Cancer Cells Using Optimal Functionalization of Targeted Carbon Quantum Dots Derived from Natural Sources Might Provide Potential Therapeutic and Cancer Bio Image Strategies by El-Brolsy, Hanaa Mohammed Elsayed Mohammed, Hanafy, Nemany A N, El-Kemary, Maged A

“…Non-small cell lung cancer (NSCLC) is an important sub-type of lung cancer associated with poor diagnosis and therapy. Innovative multi-functional systems are…”
Get full text

The Effect of Encapsulated Apigenin Nanoparticles on HePG-2 Cells through Regulation of P53 by Mabrouk Zayed, Mayada Mohamed, Sahyon, Heba A., Hanafy, Nemany A. N., El-Kemary, Maged A.

“…Apigenin (Ap) is one of the most important natural flavonoids that has potent anticancer activity. This study was designed, for the first time, to load Ap into…”
Get full text

Starch-Based Hydrogel Nanoparticles Loaded with Polyphenolic Compounds of Moringa Oleifera Leaf Extract Have Hepatoprotective Activity in Bisphenol A-Induced Animal Models by Abou El-Naga, Hend Mohamed Hasanin, El-Hashash, Samah A., Yasen, Ensaf Mokhtar, Leporatti, Stefano, Hanafy, Nemany A. N.

“…Bisphenol A (BPA) is an xenoestrogenic chemical used extensively in the fabrication of baby bottles, reusable plastic water bottles and polycarbonate plastic…”
Get full text

Formulation and optimization of folate-bovine serum albumin-coated ethoniosomes of pterostilbene as a targeted drug delivery system for lung cancer: In vitro and in vivo demonstrations by Hanafy, Nemany A. N., Abdelbadea, Reham H., Abdelaziz, Abdelaziz E., Mazyed, Eman A.

“…This study aimed to overcome the poor solubility of pterostilbene (PTS) by developing promising reconstituted proethoniosomes (PENs). The reconstituted PENs…”
Get full text

Preparation and characterization of cetuximab-loaded egg serum albumin nanoparticles and their uses as a drug delivery system against Caco-2 colon cancer cells by Salim, Elsayed I., Mosbah, Abeer M., Elhussiny, F. A., Hanafy, Nemany A. N., Abdou, Y.

“…To avoid the harmful side effects of cetuximab and improve its therapeutic efficacy, egg serum albumin (ESA) was used as a targeting drug carrier moiety for…”
Get full text

Hollow Spherical Curcumin Nanomicelles CUR@PLA@PF127: A New Trial on Breast Cancer Cells by El-Banna, Fatma S., Hanafy, Nemany A. N., Mahfouz, Magdy E., El-Kemary, Maged

“…Curcumin (CUR) nanomicelles were developed by solvent-evaporation method using Poly (lactic acid) (PLA) for the first time with Pluronic F127 (PF127) to…”
Get full text

Unveiling the therapeutic potential of anthocyanin/cisplatin-loaded chitosan nanoparticles against breast and liver cancers by Awad, Mai G., Hanafy, Nemany A. N., Ali, Ramadan A., El‑Monem, Dalia D. Abd, El-Shafiey, Sara H., El‑Magd, Mohammed A.

“…Background Liver and breast cancers are among the leading causes of cancer-related deaths worldwide, prompting researchers to seek natural anticancer agents…”
Get full text

Encapsulating TGF-β1 Inhibitory Peptides P17 and P144 as a Promising Strategy to Facilitate Their Dissolution and to Improve Their Functionalization by Hanafy, Nemany A N, Fabregat, Isabel, Leporatti, Stefano, Kemary, Maged El

“…Transforming growth factor-beta (TGFβ1) is considered as a master regulator for many intracellular signaling pathways, including proliferation, differentiation…”
Get full text

Based polymer nanoparticles from bee pollen attenuate non-small lung cancer through enhancement of apoptosis and cell cycle arrest in vivo by Salim, Elsayed I., Mahfouz, Magdy E., Eltonouby, Eman A., Hanafy, Nemany A. N., Hafez, Ezar H.

“…Bee pollen extract (BPE)-based polymer nanoparticles (BPENP) were fabricated using bovine serum albumin (BSA) and targeted with folic acid and were further…”
Get full text

Dietary Chitosan Attenuates High-Fat Diet-Induced Oxidative Stress, Apoptosis, and Inflammation in Nile Tilapia ( Oreochromis niloticus ) through Regulation of Nrf2/Kaep1 and Bcl-2/Bax Pathways by Rashwan, Aya G, Assar, Doaa H, Salah, Abdallah S, Liu, Xiaolu, Al-Hawary, Ibrahim I, Abu-Alghayth, Mohammed H, Salem, Shimaa M R, Khalil, Karim, Hanafy, Nemany A N, Abdelatty, Alaa, Sun, Luyang, Elbialy, Zizy I

“…Fatty liver injury is a prevalent condition in most farmed fish, yet the molecular mechanisms underpinning this pathology remain largely elusive. A…”
Get full text

Optimally designed theranostic system based folic acids and chitosan as a promising mucoadhesive delivery system for encapsulating curcumin LbL nano-template against invasiveness of breast cancer by Hanafy, Nemany A.N.

“…Curcumin is a potential candidate in cancer therapy due to its ability to inhibit many signalling pathways at the same time of exposure because of its unique…”
Get full text

Silymarin/curcumin loaded albumin nanoparticles coated by chitosan as muco-inhalable delivery system observing anti-inflammatory and anti COVID-19 characterizations in oleic acid triggered lung injury and in vitro COVID-19 experiment by Hanafy, Nemany A.N., El-Kemary, Maged A.

“…Respiratory infected by COVID-19 represents a major global health problem at moment even after recovery from virus corona. Since, the lung lesions for infected…”
Get full text

Micelles Structure Development as a Strategy to Improve Smart Cancer Therapy by Hanafy, Nemany A N, El-Kemary, Maged, Leporatti, Stefano

“…Micelles as colloidal suspension have attracted considerable attention due to their potential use for both cancer diagnosis and therapy. These structures have…”
Get full text

Starch based hydrogel NPs loaded by anthocyanins might treat glycogen storage at cardiomyopathy in animal fibrotic model by Hanafy, Nemany A.N.

“…Many reports have been published recently confirmed the limitation of cargo molecules delivered into the heart. This failure is mostly associated with…”
Get full text

Mucoadhesive curcumin crosslinked carboxy methyl cellulose might increase inhibitory efficiency for liver cancer treatment by Hanafy, Nemany A.N., Leporatti, Stefano, El-Kemary, Maged

“…Curcumin is a more efficient polyphenol than many chemotherapeutics. It can inhibit many signaling pathways at the same time resulting in modulation and down…”
Get full text

Potential of curcumin and niacin-loaded targeted chitosan coated liposomes to activate autophagy in hepatocellular carcinoma cells: An in vitro evaluation in HePG2 cell line by Hanafy, Nemany A.N., Sheashaa, Rehab Fouad, Moussa, Eman A., Mahfouz, Magdy E.

“…The objective of this study is to activate autophagy in hepatocellular carcinoma for the enhancement of its cellular degradation. Liposomes incorporated…”
Get full text

Extraction of chlorophyll and carotenoids loaded into chitosan as potential targeted therapy and bio imaging agents for breast carcinoma by Hanafy, Nemany A.N., Leporatti, Stefano, El-Kemary, Maged A.

“…In the current study, the treatment efficacy of ECHCAH was evaluated in vitro studies using cell viability and flow cytometry in human TNBCs. The results here…”
Get full text

Novel quercetin encapsulated chitosan functionalized copper oxide nanoparticles as anti-breast cancer agent via regulating p53 in rat model by Elsayed, Awny M., Sherif, Naglaa M., Hassan, Nahla S., Althobaiti, Fayez, Hanafy, Nemany A.N., Sahyon, Heba A.

“…This study was designed to present a new quercetin encapsulated chitosan functionalized copper oxide nanoparticle (CuO-ChNPs-Q) and assessed its anti-breast…”
Get full text