Search Results - "Hanafusa, Hiroko"

Uncovering Direct Targets of MiR-19a Involved in Lung Cancer Progression by Yamamoto, Kumiko, Ito, Sachio, Hanafusa, Hiroko, Shimizu, Kenji, Ouchida, Mamoru

“…Micro RNAs (miRNAs) regulate the expression of target genes posttranscriptionally by pairing incompletely with mRNA in a sequence-specific manner. About 30% of…”
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Novel direct targets of miR-19a identified in breast cancer cells by a quantitative proteomic approach by Ouchida, Mamoru, Kanzaki, Hirotaka, Ito, Sachio, Hanafusa, Hiroko, Jitsumori, Yoshimi, Tamaru, Seiji, Shimizu, Kenji

“…The miR-17-92 cluster encodes 7 miRNAs inside a single polycistronic transcript, and is known as a group of oncogenic miRNAs that contribute to tumorigenesis…”
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Identification of direct targets for the miR-17-92 cluster by proteomic analysis by Kanzaki, Hirotaka, Ito, Sachio, Hanafusa, Hiroko, Jitsumori, Yoshimi, Tamaru, Seiji, Shimizu, Kenji, Ouchida, Mamoru

“…MicroRNAs (miRNAs) are small non‐coding RNAs that post‐transcriptionally repress the expression of target genes. Many miRNAs have been implicated in a number…”
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Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells by Kobayashi, Kazuyasu, Ouchida, Mamoru, Tsuji, Toshiya, Hanafusa, Hiroko, Miyazaki, Masahiro, Namba, Masayoshi, Shimizu, Nobuyoshi, Shimizu, Kenji

“…The human REIC gene is a recently found mortalization-related gene and a candidate tumor suppressor gene expression of which is largely attenuated in many…”
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Genetic Alterations in the Retinoblastoma Protein-Related p107 Gene in Human Hematologic Malignancies by Takimoto, Hidetaka, Tsukuda, Kazunori, Ichimura, Koichi, Hanafusa, Hiroko, Nakamura, Akio, Oda, Megumi, Harada, Mine, Shimizu, Kenji

“…Genetic alterations in the p107 gene, a close relative of the retinoblastoma tumor suppressor gene, have never been identified in human malignancies. When we…”
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Abstract LB-246: Identification of novel direct targets of miR-19a in MCF-7 breast cancer cells by Kanzaki, Hirotaka, Ouchida, Mamoru, Ito, Sachio, Tamaru, Seiji, Hanafusa, Hiroko, Jitsumori, Yoshimi, Oka, Takashi, Shimizu, Kenji

“…Background: MicroRNAs (miRNAs) are small non-cording RNAs (20-23 nucleotides) that negatively regulate gene expression at post-transcriptional level by…”
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Genomic structure of the human ING1 gene and tumor-specific mutations detected in head and neck squamous cell carcinomas by GUNDUZ, M, OUCHIDA, M, FUKUSHIMA, K, HANAFUSA, H, ETANI, T, NISHIOKA, S, NISHIZAKI, K, SHIMIZU, K

“…We characterized the genomic structure of the human ING1 gene, a candidate tumor suppressor gene, and found that the gene has three exons. We also demonstrated…”
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Single nucleotide polymorphism of the AXIN2 gene is preferentially associated with human lung cancer risk in a Japanese population by Kanzaki, Hirotaka, Ouchida, Mamoru, Hanafusa, Hiroko, Yano, Masaaki, Suzuki, Hiromitsu, Aoe, Motoi, Imai, Kazue, Shimizu, Nobuyoshi, Nakachi, Kei, Shimizu, Kenji

“…The AXIN2 gene, a negative regulator gene of Wnt/β-catenin signaling, is a putative tumor suppressor gene on human chromosome 17q24. In the genomic locus on…”
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Single nucleotide polymorphism at codon 133 of the RASSF1 gene is preferentially associated with human lung adenocarcinoma risk by Kanzaki, Hirotaka, Hanafusa, Hiroko, Yamamoto, Hiromasa, Yasuda, Yukiko, Imai, Kazue, Yano, Masaaki, Aoe, Motoi, Shimizu, Nobuyoshi, Nakachi, Kei, Ouchida, Mamoru, Shimizu, Kenji

“…The RASSF1 gene, a putative tumor suppressor gene located on human chromosome 3p21, garners much attention for the frequent allelic loss and gene silencing via…”
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The association between RAD18 Arg302Gln polymorphism and the risk of human non-small-cell lung cancer by Kanzaki, Hirotaka, Ouchida, Mamoru, Hanafusa, Hiroko, Yamamoto, Hiromasa, Suzuki, Hiromitsu, Yano, Masaaki, Aoe, Motoi, Imai, Kazue, Date, Hiroshi, Nakachi, Kei, Shimizu, Kenji

“…Purpose The repair enzyme RAD18 plays a key role in the post-replication repair process in various organisms from yeast to human, and the molecular function of…”
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Single nucleotide polymorphism in the RAD18 gene and risk of colorectal cancer in the Japanese population by KANZAKI, Hirotaka, OUCHIDA, Mamoru, NAKACHI, Kei, SHIMIZU, Kenji, HANAFUSA, Hiroko, SAKAI, Akiko, YAMAMOTO, Hiromasa, SUZUKI, Hiromitsu, YANO, Masaaki, AOE, Motoi, IMAI, Kazue, DATE, Hiroshi

“…The RAD18 gene, located on the human chromosome 3p24-p25, plays a crucial role in post-replication repair (PRR) in various organisms from yeast to humans. In…”
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Single nucleotide polymorphisms in the EXO1 gene and risk of colorectal cancer in a Japanese population by Yamamoto, Hiromasa, Hanafusa, Hiroko, Ouchida, Mamoru, Yano, Masaaki, Suzuki, Hiromitsu, Murakami, Masakazu, Aoe, Motoi, Shimizu, Nobuyoshi, Nakachi, Kei, Shimizu, Kenji

“…EXO1 is a member of the RAD2 nuclease family and functions in DNA replication, repair and recombination. We investigated the relationship of single nucleotide…”
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Mutations of E2F-4 Trinucleotide Repeats in Colorectal Cancer with Microsatellite Instability by Yoshitaka, Tomoya, Matsubara, Nagahide, Ikeda, Masahiko, Tanino, Motohiko, Hanafusa, Hiroko, Tanaka, Noriaki, Shimizu, Kenji

“…Genetic instability at microsatellites in some colorectal cancer (CRC) have been linked to the defects of human mismatch repair genes, but the targets of these…”
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Structure of the human retinoblastoma-related p107 gene and its intragenic deletion in a B-cell lymphoma cell line by Ichimura, Koichi, Hanafusa, Hiroko, Takimoto, Hidetaka, Ohgama, Yoichiro, Akagi, Tadaatsu, Shimizu, Kenji

“…The human p107 protein shares many structural and functional features with the retinoblastoma gene product and retinoblastoma-related p130 protein. In this…”
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Human papillomavirus‐5b DNA integrated in a metastatic tumor: cloning, nucleotide sequence and genomic organization by Yabe, Yoshiro, Sakai, Akiko, Hitsumoto, Takako, Hanafusa, Hiroko, Jitsumori, Yoshimi, Ogura, Hajime

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