Search Results - "Han Soon Young"

Narcotics information management system in South Korea: system development and innovation by Kim, Sang-Yoon, Cho, Nam-Wook, Yoo, Myung-Sik, Han, Soon-Young, Oh, Jeong-Wyan

“…As the misuse and abuse of medical narcotics are increasing in South Korea, an information system for the integrated information management of medical narcotic…”
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Induction of apoptosis and CYP4A1 expression in Sprague-Dawley rats exposed to low doses of perfluorooctane sulfonate by Kim, Hyung-Sub, Kwack, Seung Jun, Han, Eui Sik, Kang, Tae Seok, Kim, Seung Hee, Han, Soon Young

“…In previous studies, perfluorooctane sulfonate (PFOS), an environmental organic compound, was reported to cause hepatotoxicity and hypolipidemia in rodents…”
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PHTHALATES INHIBIT TAMOXIFEN-INDUCED APOPTOSIS IN MCF-7 HUMAN BREAST CANCER CELLS by Kim, In Young, Han, Soon Young, Moon, Aree

“…Environmental estrogens represent a class of compounds that can mimic the function or activity of the endogenous estrogen 17β-estradiol (E2). Phthalates…”
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Evaluation of in vitro screening system for estrogenicity: comparison of stably transfected human estrogen receptor-α transcriptional activation (OECD TG455) assay and estrogen receptor (ER) binding assay by Lee, Hae Kyung, Kim, Tae Sung, Kim, Chang Yeong, Kang, Il Hyun, Kim, Mi Gyeong, Jung, Ki Kyung, Kim, Hyung Sik, Han, Soon Young, Yoon, Hae Jung, Rhee, Gyu Seek

“…The estrogenic activity of industrial chemicals, di(2-ethylhexyl) phthalate (DEHP), di(n-butyl) phthalate (DBP), benzylbutyl phthalate (BBP), diethyl phthalate…”
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NEONATAL EXPOSURE TO DI(N-BUTYL) PHTHALATE (DBP) ALTERS MALE REPRODUCTIVE-TRACT DEVELOPMENT by Kim, Hyung Sik, Kim, Tae Sung, Shin, Jae-Ho, Moon, Hyun Ju, Kang, Il Hyun, Kim, In Young, Oh, Ji Young, Han, Soon Young

“…The purpose of this study was to evaluate male reproductive-organ development in early postnatal male rats following neonatal exposure to di(n-butyl) phthalate…”
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Effect of di(n-butyl) phthalate on testicular oxidative damage and antioxidant enzymes in hyperthyroid rats by Lee, Ena, Ahn, Mee Young, Kim, Hee Jin, Kim, In Young, Han, Soon Young, Kang, Tae Seok, Hong, Jin Hwan, Park, Kui Lea, Lee, Byung Mu, Kim, Hyung Sik

“…This study compared the effects of di(n‐butyl) phthalate (DBP) on the oxidative damage and antioxidant enzymes activity in testes of hyperthyroid rats…”
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Clinical and psychological characteristics of propofol abusers in Korea: a survey of propofol abuse in 38, non-healthcare professionals by Kim, Eun-Jung, Kim, Seon-Hwa, Hyun, Yang-Jin, Noh, Yeon-Keun, Jung, Ho-Sang, Han, Soon-Young, Park, Chan-Hye, Choi, Byung Moon, Noh, Gyu-Jeong

“…The aim of this study is to investigate the characteristics of propofol abuse based on the results of a survey analysis of abusers among non-healthcare…”
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Depression risk associated with the use of 5α-reductase inhibitors versus α-blockers: A retrospective cohort study in South Korea by Yeon, Bora, Suh, Ah Young, Choi, Eunmi, Kim, Bonggi, Noh, Eunsun, Chung, Soo Youn, Han, Soon Young

“…One of the most prescribed treatments for benign prostatic hyperplasia (BPH) is 5α-reductase inhibitors (5ARI). Europe experienced recent safety issues…”
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Risk of aortic aneurysm and aortic dissection with the use of fluoroquinolones in Korea: a nested case-control study by Son, Nayeong, Choi, Eunmi, Chung, Soo Youn, Han, Soon Young, Kim, Bonggi

“…Recent studies have raised concern about the association of fluoroquinolones with an increased risk of aortic aneurysm and aortic dissection. We aimed to…”
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Effects of postnatal administration of diethylstilbestrol on puberty and thyroid function in male rats by Shin, J.H., Eulji Univ., Kyonggido (Korea R.), Kim, T.S, Kang, I.H, Kang, T.S, Moon, H.J, Han. S.Y

“…To examine the effects of diethylstilbestrol (DES) on male pubertal development and thyroid function, juvenile male Sprague-Dawley rats were given DES daily by…”
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In vitro evaluation of biomarkers for cisplatin-induced nephrotoxicity using HK-2 human kidney epithelial cells by Sohn, So-Jung, Kim, Sun Young, Kim, Hyung Sik, Chun, Young-Jin, Han, Soon Young, Kim, Seung Hee, Moon, Aree

“…► We tested in vitro biomarkers for cisplatin-induced nephrotoxicity assessment. ► Nephrotoxicity assessment in HK-2 human kidney proximal tubule cells was…”
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Risk of genital and urinary tract infections associated with SGLT‐2 inhibitors as an add‐on therapy to metformin in patients with type 2 diabetes mellitus: A retrospective cohort study in Korea by Yang, Hyeri, Choi, Eunmi, Park, Eunjun, Na, Eonji, Chung, Soo Youn, Kim, Bonggi, Han, Soon Young

“…Sodium‐glucose cotransporter‐2 (SGLT‐2) inhibitors are antidiabetic drugs with associated safety concerns regarding the risk of genital and urinary tract…”
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Assessing estrogenic activity of pyrethroid insecticides using in vitro combination assays by Kim, I.Y. (National Inst. of Toxicological Research, Seoul (Korea R.)), Shin, J.H, Kim, H.S, Lee, S.J, Kang, I.H, Kim, T.S, Moon, H.J, Choi, K.S, Moon, A, Han, S.Y

“…Pyrethroid insecticides are among the most commonly used classes of insecticides worldwide, but their endocrine disrupting activities remain unclear…”
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OECD validation of phase 3 Hershberger assay in Korea using surgically castrated male rats with coded chemicals by Moon, Hyun-Ju, Kang, Tae Seok, Kim, Tae Sung, Kang, Il Hyun, Ki, Ho Youn, Kim, Seung Hee, Han, Soon Young

“…As a participating laboratory for the OECD Hershberger validation program, we conducted a phase 3 trial to test the reliability of the Hershberger assay using…”
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POTENTIAL ESTROGENIC EFFECTS OF BISPHENOL-A ESTIMATED BY IN VITRO AND IN VIVO COMBINATION ASSAYS by KIM, Hyung Sik, HAN, Soon-Young, YOO, Sun Dong, LEE, Byung Mu, PARK, Kui Lea

“…The potential estrogenic activities of bisphenol-A were investigated in vitro (E-screen and estrogen receptor competitive binding bioassays) and in vivo…”
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OECD validation of the rodent Hershberger assay using three reference chemicals; 17α-methyltestosterone, procymidone, and p, p'-DDE by SHIN, Jae-Ho, HYUN JU MOON, IL HYUN KANG, TAE SUNG KIM, SU JUNG LEE, JI YOUN AHN, BAE, Hoon, EUI BAE JEUNG, SOON YOUNG HAN

“…The rodent Hershberger assay is being validated as an in vivo test method for detecting androgenic or antiandrogenic compounds by the Organization for Economic…”
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Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen by Lee, Y.M. (Chungbuk National University, Cheongju, Republic of Korea), Seong, M.J. (Chungbuk National University, Cheongju, Republic of Korea), Lee, J.W. (Chungbuk National University, Cheongju, Republic of Korea), Lee, Y.K. (Chungbuk National University, Cheongju, Republic of Korea), Kim, T.M. (Chungbuk National University, Cheongju, Republic of Korea), Nam, S.Y. (Chungbuk National University, Cheongju, Republic of Korea), Kim, D.J. (Chungbuk National University, Cheongju, Republic of Korea), Yun, Y.W. (Chungbuk National University, Cheongju, Republic of Korea), Kim, T.S. (Korea Food and Drug Administration, Seoul, Republic of Korea), Han, S.Y. (Korea Food and Drug Administration, Seoul, Republic of Korea), Hong, J.T. (Chungbuk National University, Cheongju, Republic of Korea), E-mail: jinthong@chungbuk.ac.kr

“…Bisphenol A (BPA), a ubiquitous environmental contaminant, has been shown to cause developmental toxicity and carcinogenic effects. BPA may have physiological…”
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Hypothyroidism protects di(n-butyl) phthalate-induced reproductive organs damage in Sprague-Dawley male rats by Lee, Ena, Kim, Hee Jin, Im, Ji Young, Kim, Jeonga, Park, Hyeyoung, Ryu, Ju Young, Lee, Jaewon, Shim, Keun Aee, Jung, Kee Kyung, Han, Soon Young, Lee, Byung Mu, Kim, Seung Hee, Kim, Hyung Sik

“…This study examined the deleterious effects of di(n-butyl) phthalate (DBP) on the male reproductive organs in hypothyroid rats. Hypothyroidism was induced in…”
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2-HYDROXYESTRADIOL INDUCES OXIDATIVE DNA DAMAGE AND APOPTOSIS IN HUMAN MAMMARY EPITHELIAL CELLS by Hurh, Yeon-Jin, Chen, Zhi-Hua, Na, Hye-Kyung, Han, Soon- Young, Surh, Young-Joon

“…Catechol estrogens, the hydroxylated metabolites of 17β-estradiol (E 2 ), have been considered to be implicated in estrogen-induced carcinogenesis…”
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PHARMACOKINETIC DISPOSITION AND TISSUE DISTRIBUTION OF BISPHENOL A IN RATS AFTER INTRAVENOUS ADMINISTRATION by Sun Dong Yoo, Beom Soo Shin, Seung Jun Kwack, Byung Mu Lee, Kui Lea Park, Soon-Young Han, Hyung Sik Kim

“…This study examined the dose-linearity pharmacokinetics of bisphenol A, a U.S. Environmental Protection Agency (EPA) classified endocrine disruptor, in rats…”
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