Search Results - "Han, Yunlin"
-
1
From SARS to MERS, Thrusting Coronaviruses into the Spotlight
Published in Viruses (14-01-2019)“…Coronaviruses (CoVs) have formerly been regarded as relatively harmless respiratory pathogens to humans. However, two outbreaks of severe respiratory tract…”
Get full text
Journal Article -
2
Ocular conjunctival inoculation of SARS-CoV-2 can cause mild COVID-19 in rhesus macaques
Published in Nature communications (02-09-2020)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly transmitted through the respiratory route, but potential extra-respiratory routes of…”
Get full text
Journal Article -
3
Primary exposure to SARS-CoV-2 protects against reinfection in rhesus macaques
Published in Science (American Association for the Advancement of Science) (14-08-2020)“…Coronavirus disease 2019 (COVID-19), which is caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global…”
Get full text
Journal Article -
4
SARS-CoV-2 crosses the blood–brain barrier accompanied with basement membrane disruption without tight junctions alteration
Published in Signal transduction and targeted therapy (06-09-2021)“…SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and model animals. However, it remains unclear whether and how SARS-CoV-2…”
Get full text
Journal Article -
5
Altered Gut Microbiota in a Mouse Model of Alzheimer's Disease
Published in Journal of Alzheimer's disease (01-01-2017)“…The topic of gut microbiota is currently attracting considerable interest as a potential factor in Alzheimer's disease (AD). However, the extent and time…”
Get more information
Journal Article -
6
Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy
Published in Cell (12-11-2020)“…Understanding how potent neutralizing antibodies (NAbs) inhibit SARS-CoV-2 is critical for effective therapeutic development. We previously described BD-368-2,…”
Get full text
Journal Article -
7
Brain Derived Exosomes Are a Double-Edged Sword in Alzheimer's Disease
Published in Frontiers in molecular neuroscience (29-05-2020)“…Brain derived exosomes (BDEs) are extracellular nanovesicles that are collectively released by all cell lineages of the central nervous system and contain…”
Get full text
Journal Article -
8
Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 via Close Contact and Respiratory Droplets Among Human Angiotensin-Converting Enzyme 2 Mice
Published in The Journal of infectious diseases (23-07-2020)“…Abstract We simulated 3 transmission modes, including close-contact, respiratory droplets and aerosol routes, in the laboratory. Severe acute respiratory…”
Get full text
Journal Article -
9
Triterpenoids and Polysaccharides from Ganoderma lucidum Improve the Histomorphology and Function of Testes in Middle-Aged Male Mice by Alleviating Oxidative Stress and Cellular Apoptosis
Published in Nutrients (09-11-2022)“…Aging is an inevitable physiological process accompanied by a decline in body physiology, including male fertility. A preparation from (GL) containing…”
Get full text
Journal Article -
10
SARS-CoV-2 Causes a Systemically Multiple Organs Damages and Dissemination in Hamsters
Published in Frontiers in microbiology (12-01-2021)“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has spread across the world and impacted global healthcare systems. For clinical patients,…”
Get full text
Journal Article -
11
PINK1 Deficiency Ameliorates Cisplatin-Induced Acute Kidney Injury in Rats
Published in Frontiers in physiology (25-09-2019)“…Mitophagy plays a key role in cleaning damaged and depolarized mitochondria to maintain cellular homeostasis and viability. Although it was originally found in…”
Get full text
Journal Article -
12
CRISPR/Cas9‐mediated targeting of the Rosa26 locus produces Cre reporter rat strains for monitoring Cre–loxP‐mediated lineage tracing
Published in The FEBS journal (01-10-2017)“…The rat is an important laboratory animal for physiological, toxicological and pharmacological studies. Clustered regularly interspaced short palindromic…”
Get full text
Journal Article -
13
PM2.5 exposure promotes asthma in aged Brown-Norway rats: Implication of multiomics analysis
Published in Ecotoxicology and environmental safety (15-09-2023)“…Children are disproportionately represented among those who suffer asthma, which is a kind of chronic airway inflammation. Asthma symptoms might worsen when…”
Get full text
Journal Article -
14
The temporal characteristics of the disruption of gut microbiota, serum metabolome, and cytokines by silica exposure in wistar rats
Published in Ecotoxicology and environmental safety (01-03-2023)“…Silicosis is one of the most frequent, rapidly developing, and lethal types of pneumoconiosis. However, our understanding of the underlying mechanisms of its…”
Get full text
Journal Article -
15
The Histopathological Investigation of Red and Blue Light Emitting Diode on Treating Skin Wounds in Japanese Big-Ear White Rabbit
Published in PloS one (27-06-2016)“…The biological effects of different wavelengths of light emitting diode (LED) light tend to vary from each other. Research into use of photobiomodulation for…”
Get full text
Journal Article -
16
Therapeutic potential of human umbilical cord mesenchymal stem cells on aortic atherosclerotic plaque in a high-fat diet rabbit model
Published in Stem cell research & therapy (15-07-2021)“…Atherosclerosis (AS) is a complex disease caused in part by dyslipidemia and chronic inflammation. AS is associated with serious cardiovascular disease and…”
Get full text
Journal Article -
17
Comprehensive Proteomic Profiling of Urinary Exosomes and Identification of Potential Non-invasive Early Biomarkers of Alzheimer's Disease in 5XFAD Mouse Model
Published in Frontiers in genetics (05-11-2020)“…Alzheimer's disease (AD) is an incurable neurodegenerative disease characterized by irreversible progressive cognitive deficits. Identification of candidate…”
Get full text
Journal Article -
18
A comparative study of mouse bone marrow mesenchymal stem cells isolated using three easy‐to‐perform approaches
Published in FEBS open bio (01-12-2022)“…Mouse bone marrow mesenchymal stem cells (mBM‐MSCs) are important for preclinical tissue regeneration and repair studies. In the present study, we isolated…”
Get full text
Journal Article -
19
Allogeneic Adipose-Derived Mesenchymal Stem Cell Transplantation Alleviates Atherosclerotic Plaque by Inhibiting Ox-LDL Uptake, Inflammatory Reaction and Endothelial Damage in Rabbits
Published in Cells (Basel, Switzerland) (26-07-2023)“…Atherosclerosis (AS) is a chronic inflammatory disease of arteries fueled by lipids. It is a major cause of cardiovascular morbidity and mortality. Mesenchymal…”
Get full text
Journal Article -
20
Integrated histopathological, lipidomic, and metabolomic profiles reveal mink is a useful animal model to mimic the pathogenicity of severe COVID-19 patients
Published in Signal transduction and targeted therapy (28-01-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted on mink farms between minks and humans in many countries. However, the systemic…”
Get full text
Journal Article