Search Results - "Han, Yoo Jane"
-
1
Subtype-specific expression of MELK is partly due to copy number alterations in breast cancer
Published in PloS one (24-06-2022)“…Maternal embryonic leucine-zipper kinase (MELK) regulates cell cycle progression and is highly expressed in many cancers. The molecular mechanism of MELK…”
Get full text
Journal Article -
2
LncRNA BLAT1 is Upregulated in Basal-like Breast Cancer through Epigenetic Modifications
Published in Scientific reports (22-10-2018)“…Long-noncoding RNAs (lncRNAs) have been shown to participate in oncogenesis across a variety of cancers and may represent novel therapeutic targets. However,…”
Get full text
Journal Article -
3
An enhancer variant associated with breast cancer susceptibility in Black women regulates TNFSF10 expression and antitumor immunity in triple-negative breast cancer
Published in Human molecular genetics (01-01-2023)“…Women of African ancestry have the highest mortality from triple-negative breast cancer (TNBC) of all racial groups. To understand the genomic basis of breast…”
Get full text
Journal Article -
4
The VEGF-Hypoxia Signature is Upregulated in Basal like Breast Tumors from Women of African Ancestry and Associated with Poor Outcomes in Breast Cancer
Published in Clinical cancer research (03-06-2024)“…Black women experience the highest breast cancer mortality rate compared to women of other racial/ethnic groups. To gain a deeper understanding of breast…”
Get full text
Journal Article -
5
The BRCA1 Pseudogene Negatively Regulates Antitumor Responses through Inhibition of Innate Immune Defense Mechanisms
Published in Cancer research (Chicago, Ill.) (15-03-2021)“…Innate immune defense mechanisms play a pivotal role in antitumor responses. Recent evidence suggests that antiviral innate immunity is regulated not only by…”
Get full text
Journal Article -
6
The BRCA1 Pseudogene Negatively Regulates Anti-Tumor Responses through Inhibition of Innate Immune Defense Mechanisms
Published in Cancer research (Chicago, Ill.) (20-01-2021)“…Innate immune defense mechanisms play a pivotal role in anti-tumor responses. Recent evidence suggests that antiviral innate immunity is regulated not only by…”
Get full text
Journal Article -
7
Abstract 386: BACH1 is a key regulator of the tumor hypoxia response
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Hypoxia is an important hallmark of aggressive solid tumors and a key driver of metastasis and resistance to therapy. Hypoxic stress induces the…”
Get full text
Journal Article -
8
Abstract C121: Racial differences in expression of the oxygen-sensor BACH1 in breast cancer
Published in Cancer epidemiology, biomarkers & prevention (21-09-2024)“…Abstract Hypoxia is an important hallmark of aggressive solid tumors and a key driver of metastasis and resistance to therapy. Hypoxic stress induces the…”
Get full text
Journal Article