Search Results - "Han, Wenruo"

Renal xenografts from triple-transgenic pigs are not hyperacutely rejected but cause coagulopathy in non-immunosuppressed baboons by COWAN, P. J, AMINIAN, A, NOTTLE, M. B, PEARSE, M. J, SALVARIS, E, SHINKEL, T. A, STAINSBY, G. V, STEWART, A. B, D'APICE, A. J. F, BARLOW, H, BROWN, A. A, CHEN, C.-G, FISICARO, N, FRANCIS, D. M. A, GOODMAN, D. J, WENRUO HAN, KUREK, M

“…The genetic modification of pigs is a powerful strategy that may ultimately enable successful xenotransplantation of porcine organs into humans. Transgenic…”
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Anti-Gal antibody-mediated allograft rejection in α1,3-galactosyltransferase gene knockout mice: A model of delayed xenograft rejection by PEARSE, M. J, WITORT, E, MOTTRAM, P, WENRUO HAN, MURRAY-SEGAL, L, ROMANELLA, M, SALVARIS, E, SHINKEL, T. A, GOODMAN, D. J, D'APICE, A. J

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Long-term survival of segmental pancreas isografts in NOD/Lt mice treated with anti-CD4 and anti-CD8 monoclonal antibodies by MOTTRAM, P. L, MURRAY-SEGAL, L. J, WENRUO HAN, MAGUIRE, J, STEIN-OAKLEY, A, MANDEL, T. E

“…Long-term survival of segmental pancreas isografts in NOD/Lt mice treated with anti-CD4 and anti-CD8 monoclonal antibodies. P L Mottram , L J Murray-Segal , W…”
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Remission and pancreas isograft survival in recent onset diabetic NOD mice after treatment with low-dose anti-CD3 monoclonal antibodies by Mottram, Patricia L., Murray-Segal, Lisa J., Han, Wenruo, Maguire, Julie, Stein-Oakley, Alicia N.

“…Diabetes in NOD mice is an autoimmune disease similar to Type I diabetes in humans. Prior to hypoglycemia, changes in the islet infiltrate led to autoreactive…”
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Blockade of the CD28 and CD40 pathways result in the acceptance of pig and rat islet xenografts but not rat cardiac grafts in mice by Lehnert, Anne M, Mottram, Patricia L, Han, Wenruo, Walters, Stacey N, Patel, Anita T, Hawthorne, Wayne J, Cowan, Peter J, d'Apice, Anthony J.F, O'Connell, Philip J

“…Previously, we demonstrated that combination CTLA4-Fc and anti-CD40L mAb treatment results in tolerance to concordant, cellular islet xenografts. The aim of…”
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DISSEMINATED INTRAVASCULAR COAGULATION COMPLICATES TRANSGENIC PIG RENAL XENOTRANSPLANTATION IN NON-IMMUNOSUPPRESSED BABOONS: Abstract# 1174 by Cowan, Peter J., Goodman, David J., Aminian, Atousa, Brown, Ainslie, Barlow, Helen, Shinkel, Trixie A., Kurek, Margarita, Francis, David M., Han, Wenruo, Stewart, Alastair, Nottle, Mark, Chen, Ghao-Guang, Salvaris, Evelyn, Pearse, Martin J., dʼApice, Anthony J.

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Hyperacute rejection of vascularized heart transplants in BALB/c Gal knockout mice by Gock, Hilton, Salvaris, Evelyn, Murray-Segal, Lisa, Mottram, Patricia, Han, Wenruo, Pearse, Martin J., Goodman, David J., Cowan, Peter J., D'apice, Anthony J. F.

“…: Pig‐to‐primate vascularized xenografts undergo hyperacute rejection (HAR). This results from pre‐formed xenoreactive antibodies directed against…”
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ANTI-GAL ANTIBODY-MEDIATED ALLOGRAFT REJECTION IN ??1,3-GALACTOSYLTRANSFERASE GENE KNOCKOUT MICE: A Model of Delayed Xenograft Rejection by Pearse, Martin J., Witort, Ewa, Mottram, Patricia, Han, Wenruo, Murray-Segal, Lisa, Romanella, Margarita, Salvaris, Evelyn, Shinkel, T. A., Goodman, David J., d'Apice, Anthony J.

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Naturally acquired anti-αGal antibodies in a murine allograft model similar to delayed xenograft rejection by Salvaris, Evelyn, Gock, Hilton, Han, Wenruo, Murray-Segal, Lisa, Barlow, Helen, Mottram, Patricia, Pearse, Martin, Cowan, Peter, Goodman, David, D'Apice, Anthony J. F.

“…: Antibodies directed against galactose‐α1,3‐galactose (αGal) are believed to play an important a role in the pathogenesis of delayed xenograft rejection…”
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Transgenic anti-CD4 monoclonal antibody secretion by mouse segmental pancreas allografts promotes long term survival by Mottram, Patricia L, Murray-Segal, Lisa J, Han, Wenruo, Zhan, Yifan, Brady, Jamie L, Lew, Andrew M

“…To compare the effectiveness of transgenic and systemic monoclonal antibody therapy for pancreas transplantation, vascularised segmental pancreas allografts…”
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