Search Results - "Han, Sungho"

Phase transitions in confined water nanofilms by Han, Sungho, Choi, M. Y, Kumar, Pradeep, Stanley, H. Eugene

“…Bulk water has three phases: solid, liquid and vapour. In addition to undergoing a phase transition (of the first order) between them, liquid and vapour can…”
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Inspection of Underwater Hull Surface Condition Using the Soft Voting Ensemble of the Transfer-Learned Models by Kim, Byung Chul, Kim, Hoe Chang, Han, Sungho, Park, Dong Kyou

“…In this study, we propose a method for inspecting the condition of hull surfaces using underwater images acquired from the camera of a remotely controlled…”
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Trametinib activates endogenous neurogenesis and recovers neuropathology in a model of Alzheimer’s disease by Kim, Mi-Yeon, Kim, Mi Jeong, Lee, Changyeob, Lee, Juwon, Kim, Sang Seong, Hong, Sungho, Kim, Hyoung Tae, Seo, Jinsoo, Yoon, Ki-Jun, Han, Sungho

“…Enhancing adult neurogenesis in the brain has been suggested as a potential therapeutic strategy for AD. We developed a screening platform, ATRIVIEW ® , for…”
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Multiresolution molecular dynamics simulations reveal the interplay between conformational variability and functional interactions in membrane‐bound cytochrome P450 2B4 by Han, Sungho Bosco, Teuffel, Jonathan, Mukherjee, Goutam, Wade, Rebecca C.

“…Cytochrome P450 2B4 (CYP 2B4) is one of the best‐characterized CYPs and serves as a key model system for understanding the mechanisms of microsomal class II…”
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GNUV201, a novel human/mouse cross-reactive and low pH-selective anti-PD-1 monoclonal antibody for cancer immunotherapy by Kim, Hae-Mi, Kim, Kyoung-Jin, Lee, Kwanghyun, Yoon, Myeong Jin, Choih, Jenny, Hong, Tae-Joon, Cho, Eun Ji, Jung, Hak-Jun, Kim, Jayoung, Park, Ji Soo, Na, Hye Young, Heo, Yong-Seok, Park, Chae Gyu, Park, Heungrok, Han, Sungho, Bae, Donggoo

“…Several PD-1 antibodies approved as anti-cancer therapies work by blocking the interaction of PD-1 with its ligand PD-L1, thus restoring anti-cancer T cell…”
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Structure and dynamics in the lithium solvation shell of nonaqueous electrolytes by Han, Sungho

“…The solvation of a lithium ion has been of great importance to understand the structure and dynamics of electrolytes. In mixed electrolytes of cyclic and…”
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1173 GNUV205, a bifunctional protein of engineered IL-2 fused with a novel anti-PD1 antibody, exhibits superior tumor suppressing efficacy in vivo by Kim, June Myoung, Choi, Eunju, Lee, Kwanghyun, Jung, Hak-Jun, Shin, Hyun Soo, Choih, Jenny, Park, Heungrok, Han, Sungho, Bae, Donggoo

“…BackgroundWhile the introduction of immuno-oncology drugs, especially anti-PD-(L)1s, has revolutionized the strategy for fighting against cancer, there is…”
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Anionic effects on the structure and dynamics of water in superconcentrated aqueous electrolytes by Han, Sungho

“…Dissolved ions in aqueous solutions are ubiquitous in a variety of systems and the addition of ions to water gives rise to dramatic effects on the properties…”
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Mode-Manipulated Multimode Cavity for Quantum Memory by Jang, Tae Hwan, Lee, Jaehyeong, Shin, Jaeho, Kang, Jinhyoun, Han, Sungho, Jeon, Insu, Chakram, Srivatsan, Schuster, David I., Kwon, Hyeokshin

“…In this study, a quasi-elliptical geometry and the iris technique are applied to a multimode cavity to manipulate the resonant mode in the desired direction…”
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Dynamic features of water molecules in superconcentrated aqueous electrolytes by Han, Sungho

“…An existence of ions dissolved in water has significant effects on bulk properties of water. Superconcentrated conditions have been recently proposed to…”
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Anomalous change in the dynamics of a supercritical fluid by Han, Sungho

“…We perform molecular dynamics simulations to investigate dynamical properties of a supercritical Lennard-Jones fluid. We find that in the supercritical region…”
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A salient effect of density on the dynamics of nonaqueous electrolytes by Han, Sungho

“…The mobility and solvation of lithium ions in electrolytes are crucial for the performance and safety of lithium ion batteries. It has been known that a single…”
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Localized Disruption of Narp in Medial Prefrontal Cortex Blocks Reinforcer Devaluation Performance by Johnson, Alexander W, Han, Sungho, Blouin, Ashley M, Saini, Jasjit, Worley, Paul F, During, Matthew J, Holland, Peter C, Baraban, Jay M, Reti, Irving M

“…Neuronal activity regulated pentraxin (Narp) is a secreted protein that regulates [alpha]-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptors (AMPAR)…”
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Dynamics of two-dimensional monolayer water confined in hydrophobic and charged environments by Kumar, Pradeep, Han, Sungho

“…We perform molecular dynamics simulations to study the effect of charged surfaces on the intermediate and long time dynamics of water in nanoconfinements…”
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Glutarate Hydroxylation by the Carbon Starvation-Induced Protein D: A Computational Study into the Stereo- and Regioselectivities of the Reaction by Han, Sungho Bosco, Ali, Hafiz Saqib, de Visser, Sam P

“…The carbon starvation-induced protein D (CsiD) is a recently characterized iron­(II)/α-ketoglutarate-dependent oxygenase that activates a glutarate molecule as…”
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Candidate Source of Flux Noise in SQUIDs: Adsorbed Oxygen Molecules by Wang, Hui, Shi, Chuntai, Hu, Jun, Han, Sungho, Yu, Clare C, Wu, R Q

“…A major obstacle to using superconducting quantum interference devices (SQUIDs) as qubits is flux noise. We propose that the heretofore mysterious spins…”
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Druggability Assessment in TRAPP Using Machine Learning Approaches by Yuan, Jui-Hung, Han, Sungho Bosco, Richter, Stefan, Wade, Rebecca C, Kokh, Daria B

“…Accurate protein druggability predictions are important for the selection of drug targets in the early stages of drug discovery. Because of the flexible nature…”
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Simulation of the Positive Inotropic Peptide S100A1ct in Aqueous Environment by Gaussian Accelerated Molecular Dynamics by Glaser, Manuel, Bruce, Neil J, Han, Sungho Bosco, Wade, Rebecca C

“…The S100A1ct peptide, consisting of the C-terminal 20 residues of the S100A1 protein fused to an N-terminal 6-residue hydrophilic tag, has been found to exert…”
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MEK1/2 inhibition rescues neurodegeneration by TFEB-mediated activation of autophagic lysosomal function in a model of Alzheimer’s Disease by Chun, Yoon Sun, Kim, Mi-Yeon, Lee, Sun-Young, Kim, Mi Jeong, Hong, Tae-Joon, Jeon, Jae Kyong, Ganbat, Dulguun, Kim, Hyoung Tae, Kim, Sang Seong, Kam, Tae-In, Han, Sungho

“…Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder, which is characterized by cognitive deficit due to synaptic loss and neuronal death…”
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A Comparative Analysis of Regional Innovation Characteristics Using an Innovation Actor Framework by Han, Sungho, Yoo, Gwang Min, Kwak, Sunjoo

“…Knowledge, a fundamental component of innovation, expands more effectively when innovation actors are in geographical proximity to each other. Innovation in…”
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