Search Results - "Han, Orjin"
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The Role of BMP Signaling in Endothelial Heterogeneity
Published in Frontiers in cell and developmental biology (21-06-2021)“…Bone morphogenetic proteins (BMPs), which compose the largest group of the transforming growth factor-β (TGF-ß) superfamily, have been implied to play a…”
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Bone Morphogenetic Protein Signaling Restricts Proximodistal Extension of the Ventral Fin Fold
Published in Frontiers in cell and developmental biology (30-11-2020)“…Unpaired fins, which are the most ancient form of locomotory appendages in chordates, had emerged at least 500 million years ago. While it has been suggested…”
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Analyses of Avascular Mutants Reveal Unique Transcriptomic Signature of Non-conventional Endothelial Cells
Published in Frontiers in cell and developmental biology (23-11-2020)“…Endothelial cells appear to emerge from diverse progenitors. However, to which extent their developmental origin contributes to define their cellular and…”
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Comparison of transcriptomic changes between zebrafish and mice upon high fat diet reveals evolutionary convergence in lipid metabolism
Published in Biochemical and biophysical research communications (01-10-2020)“…Hyperlipidemia is an abnormal elevation of lipid level in blood, which affects more than 100 million people in US. Zebrafish has recently emerged as a model to…”
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Transcriptomic analysis identifies novel targets for individual bone morphogenetic protein type 1 receptors in endothelial cells
Published in The FASEB journal (01-03-2021)“…Bone Morphogenetic Protein (BMP) signaling regulates diverse biological processes. Upon ligand binding, BMP receptors (BMPRs) phosphorylate SMAD1/5 and other…”
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BMPR1A promotes ID2–ZEB1 interaction to suppress excessive endothelial to mesenchymal transition
Published in Cardiovascular research (02-05-2023)“…Abstract Aims Components of bone morphogenetic protein (BMP) signalling have been implicated in both pathogenesis of pulmonary arterial hypertension (PAH) and…”
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ACVR1/ALK2-p21 signaling axis modulates proliferation of the venous endothelium in the retinal vasculature
Published in Angiogenesis (London) (01-11-2024)“…The proliferation of the endothelium is a highly coordinated process to ensure the emergence, expansion, and homeostasis of the vasculature. While Bone…”
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Pax9 is essential for granulopoiesis but dispensable for erythropoiesis in zebrafish
Published in Biochemical and biophysical research communications (01-01-2021)“…Paired Box (Pax) gene family, a group of transcription regulators have been implicated in diverse physiological processes. However, their role during…”
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Evaluation of a BioRad Avidity assay for identification of recent HIV-1 infections using dried serum or plasma spots
Published in Journal of virological methods (01-04-2019)“…•Evaluation of an avidity-based recency-assay using a modified protocol of the European BioRad Geenscreen™ HIV-1/2 ELISA (‘BioRad Europe Avidity’).•Mean…”
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