Search Results - "Han, Moon Hi"
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First Synthesis of Novel Aminophenyl Pyridinium-5-(hydroxybenzoyl)-hydrazonomethyl-2-oxothiazol-3-ide Derivatives and Evaluation of Their Anticancer Activities
Published in Chemical & pharmaceutical bulletin (2015)“…The first total synthesis for large-scale production and anticancer activity of novel…”
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2
p53 Negatively Regulates cdc2 Transcription via the CCAAT-binding NF-Y Transcription Factor
Published in The Journal of biological chemistry (15-10-1999)“…The p53 tumor suppressor protein regulates the transcription of regulatory genes involved in cell cycle arrest and apoptosis. We have reported previously that…”
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First Synthesis of Novel Aminophenyl Pyridinium-5-(hydroxybenzoyl)-hydrazonomethyl-2-oxothiazol-3-ide Derivatives and Evaluation of Their Anticancer Activities
Published in Chemical and Pharmaceutical Bulletin (01-10-2015)“…The first total synthesis for large-scale production and anticancer activity of novel…”
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4
Protein Microarray System for Detecting Protein−Protein Interactions Using an Anti-His-Tag Antibody and Fluorescence Scanning: Effects of the Heme Redox State on Protein−Protein Interactions of Heme-Regulated Phosphodiesterase from Escherichia coli
Published in Analytical chemistry (Washington) (15-11-2004)“…A highly sensitive microarray system for detecting protein-protein interactions has been developed. This method was successfully applied to analyze the…”
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5
Profiling of differential protein expression in angiogenin-induced HUVECs using antibody-arrayed ProteoChip
Published in Proteomics (Weinheim) (01-02-2006)“…ProteoChip has been developed as a novel protein microarray technology. So far it has been applied in new lead screening and molecular diagnosticsand we expect…”
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ProteoChip: A highly sensitive protein microarray prepared by a novel method of protein immobilization for application of protein-protein interaction studies
Published in Proteomics (Weinheim) (01-12-2003)“…We have developed a highly sensitive microarray protein chip, ProteoChip, coated with ProLinker™, novel calixcrown derivatives with a bifunctional coupling…”
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Pharmacoproteomic Analysis of a Novel Cell-permeable Peptide Inhibitor of Tumor-induced Angiogenesis
Published in Molecular & cellular proteomics (01-08-2011)“…P11, a novel peptide ligand containing a PDZ-binding motif (Ser-Asp-Val) with high affinity to integrin αvβ3 was identified from a hexapeptide library…”
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Calixarene derivative as a tool for highly sensitive detection and oriented immobilization of proteins in a microarray format through noncovalent molecular interaction
Published in The FASEB journal (01-08-2005)“…ABSTRACTOne important factor in fabricating protein microarray is to immobilize proteins without losing their activity on a solid phase. To keep them…”
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Inhibitory effect of Sanguisorba officinalis ethanol extract on NO and PGE2 production is mediated by suppression of NF-κB and AP-1 activation signaling cascade
Published in Journal of ethnopharmacology (08-03-2011)“…So-EE has a potent anti-inflammatory activity mediated by NF-κB, and AP-1 inhibitory properties linked to the suppression of Src and MAPK activation…”
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10
Site-specific inhibition of integrin αvβ3-vitronectin association by a ser-asp-val sequence through an Arg-Gly-Asp-binding site of the integrin
Published in Proteomics (Weinheim) (2010)“…A functional proteomic technology using protein chip and molecular simulation was used to demonstrate a novel biomolecular interaction between P11, a peptide…”
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High-throughput screening of novel peptide inhibitors of an integrin receptor from the hexapeptide library by using a protein microarray chip
Published in Journal of biomolecular screening (01-12-2004)“…Protein microarray is an emerging technology that makes high-throughput analysis possible for protein-protein interactions and analysis of proteome and…”
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12
Constitutive activation of cyclin B1-associated cdc2 kinase overrides p53-mediated G2-M arrest
Published in Cancer research (Chicago, Ill.) (01-02-2000)“…Recent studies have suggested that p53 regulates the G2 checkpoint in the cell cycle and that this function is required for the maintenance of genomic…”
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13
Small molecule inhibitors of IκB kinase β: A chip-based screening and molecular docking simulation
Published in Bioorganic & medicinal chemistry (01-05-2020)“…[Display omitted] A chip-based screening system for IκB kinase β (IKKβ) has been developed by physically immobilizing the substrate IκBα on a glass matrix…”
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14
Mutational and Kinetic Evaluation of Conserved His-123 in Dual Specificity Protein-tyrosine Phosphatase Vaccinia H1-related Phosphatase
Published in The Journal of biological chemistry (20-07-2001)“…Active-site cysteine strategically positioned in the P-loop of protein-tyrosine phosphatases has been suggested to be further stabilized by hydrogen bonding…”
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15
Anti-inflammatory activity of ethanol extract derived from Phaseolus angularis beans
Published in Journal of ethnopharmacology (11-10-2011)“…Phaseolus angularis Wight (adzuki bean) is an ethnopharmacologically well-known folk medicine that is prescribed for infection, edema, and inflammation of the…”
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Inhibitors of Aurora Kinases Screened by a Chip‐based Assay System
Published in Bulletin of the Korean Chemical Society (01-12-2019)“…Aurora kinases (AKs) are involved in cell division and thus an important target for cancer therapy. We have developed a chip‐based AK assay system that can be…”
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Site-specific inhibition of integrin alpha v beta 3-vitronectin association by a ser-asp-val sequence through an Arg-Gly-Asp-binding site of the integrin
Published in Proteomics (Weinheim) (01-01-2010)“…A functional proteomic technology using protein chip and molecular simulation was used to demonstrate a novel biomolecular interaction between P11, a peptide…”
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18
Characterization of a murine-human chimeric antibody with specificity for the pre-S2 surface antigen of hepatitis B virus expressed in baculovirus-infected insect cells
Published in Virus research (01-10-1995)“…We have produced and characterized a murine-human chimeric antibody with specificity for the pre-S2 surface antigen of hepatitis B virus (HBV) in…”
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Cloning, expression and characterization of a murine-human chimeric antibody with specificity for pre-S2 surface antigen of hepatitis B virus
Published in Molecular immunology (01-12-1993)“…The cloning, expression and characterization of a murine-human chimeric antibody with specificity for the pre-S2 surface antigen (Ag) of hepatitis B virus…”
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Cloning and characterization of cDNAs coding for heavy and light chains of a monoclonal antibody specific for pre-S2 antigen of hepatitis B virus
Published in Gene (16-11-1992)“…Binding specificity of a monoclonal antibody (mAb) (kappa, gamma 2b) H8 which can react with the pre-S2 peptide of hepatitis B virus (HBV) was determined by…”
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