Search Results - "Han, Linyu"
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LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization
Published in Journal of experimental & clinical cancer research (18-04-2023)“…Gastric cancer remains the leading cause of cancer death in the world. It is increasingly evident that long non-coding RNAs (lncRNAs) transcribed from the…”
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2
LINC00921 reduces lung cancer radiosensitivity by destabilizing NUDT21 and driving aberrant MED23 alternative polyadenylation
Published in Cell reports (Cambridge) (26-12-2023)“…Alternative polyadenylation (APA) plays a major role in controlling transcriptome diversity and therapeutic resistance of cancers. However, long non-coding…”
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3
Evaluation of Bufadienolides as the Main Antitumor Components in Cinobufacin Injection for Liver and Gastric Cancer Therapy
Published in PloS one (12-01-2017)“…Cinobufacin injection, also known as huachansu, is a preparation form of Cinobufacini made from Cinobufacin extract liquid. Despite that Cinobufacin injection…”
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4
New insights on the interplays between m6A modifications and microRNA or lncRNA in gastrointestinal cancers
Published in Frontiers in cell and developmental biology (19-06-2023)“…N 6 -Methyladenosine (m 6 A) methylation is one of the most extremely examined RNA modifications. M 6 A modification evidently impacts cancer development by…”
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5
Noncoding RNAs: an emerging modulator of drug resistance in pancreatic cancer
Published in Frontiers in cell and developmental biology (25-07-2023)“…Pancreatic cancer is the eighth leading cause of cancer-related deaths worldwide. Chemotherapy including gemcitabine, 5-fluorouracil, adriamycin and cisplatin,…”
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CircPDIA4 Induces Gastric Cancer Progression by Promoting ERK1/2 Activation and Enhancing Biogenesis of Oncogenic circRNAs
Published in Cancer research (Chicago, Ill.) (15-02-2023)“…Circular RNAs (circRNA) are a group of noncoding, covalently uninterrupted loop transcripts, most of which remain to be functionally characterized. Here, we…”
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Comparative study on the interaction between transferrin and flavonols: Experimental and computational modeling approaches
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy (05-03-2023)“…[Display omitted] •The quenching mechanism of transferrin by flavonols is static quenching.•Flavonols have a moderate affinity with transferrin.•Myricetin may…”
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Super Enhancer-Regulated LncRNA LINC01089 Induces Alternative Splicing of DIAPH3 to Drive Hepatocellular Carcinoma Metastasis
Published in Cancer research (Chicago, Ill.) (15-12-2023)“…Hepatocellular carcinoma (HCC) is one of the most lethal neoplasms and has a 5-year survival rate of only 18% in patients with metastatic diseases. Epigenetic…”
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9
The ASH1L-AS1-ASH1L axis controls NME1-mediated activation of the RAS signaling in gastric cancer
Published in Oncogene (10-11-2023)“…Gastric cancer (GC) is one of the most leading cause of malignancies. However, the molecular mechanisms underlying stomach carcinogenesis remain incompletely…”
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10
LINC01226 promotes gastric cancer progression through enhancing cytoplasm-to-nucleus translocation of STIP1 and stabilizing β-catenin protein
Published in Cancer letters (28-11-2023)“…Gastric cancer (GC) remains one of the most common malignances and the leading cause of cancer-related mortality worldwide. Although the critical role of…”
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11
In Situ Probe Supramolecular Self-Assembly Dynamics and Chirality Transfer Mechanism at Air–Water Interface
Published in The journal of physical chemistry letters (21-04-2022)“…The study of supramolecular self-assembly dynamics and the chirality transfer mechanism is of importance to the rational design of potentially functional…”
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12
The RNA editing enzyme ADAR modulated by the rs1127317 genetic variant diminishes EGFR-TKIs efficiency in advanced lung adenocarcinoma
Published in Life sciences (1973) (01-05-2022)“…The adenosine-to-inosine (A-to-I) RNA editing controlled by the editing genes are known to diversify transcripts in human. Aberrant A-to-I editing due to…”
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13
MAZ promotes thyroid cancer progression by driving transcriptional reprogram and enhancing ERK1/2 activation
Published in Cancer letters (10-10-2024)“…Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancies worldwide. Oncogenic transcription factors (TFs) drive transcriptional…”
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Genome-wide functional integration identified MAZ-controlled RPS14 dysregulation in hepatocellular carcinoma
Published in Archives of toxicology (01-03-2024)“…Chronic infection with Hepatitis B virus (HBV) significantly increases the risk of hepatocellular carcinoma (HCC), particularly in Eastern Asia. However, only…”
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15
The allelic regulation of tumor suppressor ADARB2 in papillary thyroid carcinoma
Published in Endocrine-related cancer (01-01-2023)“…Papillary thyroid cancer (PTC) is one of the histological subtypes of thyroid cancer which is the most common endocrine malignancy in the world. The disrupted…”
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Upregulated Circular RNA KIF4A Promotes Cell Migration and Invasion by Regulating MicroRNA-144-3p/EZH2 Axis in Gastric Cancer
Published in Journal of oncology (15-04-2022)“…Accumulating evidence has shown that circular RNAs (circRNAs) serve a critical regulatory role in various human cancers, including gastric cancer (GC), and in…”
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17
Inflammatory cytokine-regulated LNCPTCTS suppresses thyroid cancer progression via enhancing Snail nuclear export
Published in Cancer letters (28-10-2023)“…Lymph node metastases are commonly observed in diverse malignancies where they promote cancer progression and poor outcomes, although the molecular basis is…”
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18
Evolution of template-assisted two-dimensional porphyrin chiral grating structure by directed self-assembly using chiral second harmonic generation microscopy
Published in Chinese chemical letters (01-10-2024)“…Directed self-assembly has been used to create micro-nano scale patterns, including chiral periodic structures of organic molecules, for potential applications…”
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19
New insights on the interplays between m 6 A modifications and microRNA or lncRNA in gastrointestinal cancers
Published in Frontiers in cell and developmental biology (2023)“…N -Methyladenosine (m A) methylation is one of the most extremely examined RNA modifications. M A modification evidently impacts cancer development by…”
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20
The Allelic Expression of RNA Editing Gene ADARB1 in Hepatocellular Carcinoma Treated with Transarterial Chemoembolization
Published in Pharmacogenomics and personalized medicine (01-01-2023)“…Transarterial chemoembolization (TACE) is the commonly used therapy of unresectable hepatocellular carcinoma (HCC), though the prognosis of different…”
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