Search Results - "Han, Jin‐Kwan"

Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains by Kim, Jinuk, Han, Wonhee, Park, Taeyong, Kim, Eun Jin, Bang, Injin, Lee, Hyun Sik, Jeong, Yejin, Roh, Kyeonghwan, Kim, Jeesoo, Kim, Jong-Seo, Kang, Chanhee, Seok, Chaok, Han, Jin-Kwan, Choi, Hee-Jung

“…Low-density lipoprotein receptor-related protein 6 (LRP6) is a coreceptor of the β-catenin-dependent Wnt signaling pathway. The LRP6 ectodomain binds Wnt…”
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Transmembrane protein 150b attenuates BMP signaling in the Xenopus organizer by Keum, Byeong‐Rak, Yeo, Inchul, Koo, Youngmu, Han, Wonhee, Choi, Sun‐Cheol, Kim, Gun‐Hwa, Han, Jin‐Kwan

“…The vertebrate organizer is a specified embryonic tissue that regulates dorsoventral patterning and axis formation. Although numerous cellular signaling…”
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Heterogeneous osteoimmune profiles via single-cell transcriptomics in osteoporotic patients who fail bisphosphonate treatment by Keum, Byeong-Rak, Kim, Hong Jin, Lee, Juhun, Lee, Minji, Hong, Sin-Hyoung, Chang, Ha Kyun, Han, Jin-Kwan, Kim, Sanguk, Chang, Dong-Gune, Kim, Gun-Hwa

“…Postmenopausal osteoporosis arises from imbalanced osteoclast and osteoblast activity, and mounting evidence suggests a role for the osteoimmune system in bone…”
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UCHL5 controls β-catenin destruction complex function through Axin1 regulation by Han, Wonhee, Koo, Youngmu, Chaieb, Leila, Keum, Byeong-Rak, Han, Jin-Kwan

“…Wnt/β-catenin signaling is crucially involved in many biological processes, from embryogenesis to cancer development. Hence, the complete understanding of its…”
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RNF2 regulates Wnt/ß-catenin signaling via TCF7L1 destabilization by Koo, Youngmu, Han, Wonhee, Keum, Byeong-Rak, Lutz, Leila, Yun, Sung Ho, Kim, Gun-Hwa, Han, Jin-Kwan

“…The Wnt signaling pathway is a crucial regulator of various biological processes, such as development and cancer. The downstream transcription factors in this…”
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Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation by Gwak, Jungsug, Hwang, Sun Gwan, Park, Hyung-Soon, Choi, Sang Rak, Park, Sun-Hee, Kim, Hyunjoon, Ha, Nam-Chul, Bae, Sung Jin, Han, Jin-Kwan, Kim, Dong-Eun, Cho, Jeong Woo, Oh, Sangtaek

“…The Wnt/β-catenin pathway plays important roles in the differentiation of multiple cell types, including mesenchy- mal stem cells. Using a cell-based chemical…”
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Direct Inhibition of GSK3β by the Phosphorylated Cytoplasmic Domain of LRP6 in Wnt/β-Catenin Signaling by Piao, Shunfu, Lee, Sun-Hye, Kim, Hyunjoon, Yum, Soohwan, Stamos, Jennifer L., Xu, Yongbin, Lee, Su-Jin, Lee, Jaewon, Oh, Sangtaek, Han, Jin-Kwan, Park, Bum-Joon, Weis, William I., Ha, Nam-Chul

“…Wnt/β-catenin signaling plays a central role in development and is also involved in a diverse array of diseases. Binding of Wnts to the coreceptors Frizzled…”
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Head formation requires Dishevelled degradation that is mediated by March2 in concert with Dapper1 by Lee, Hyeyoon, Cheong, Seong-Moon, Han, Wonhee, Koo, Youngmu, Jo, Saet-Byeol, Cho, Gun-Sik, Yang, Jae-Seong, Kim, Sanguk, Han, Jin-Kwan

“…Dishevelled (Dvl/Dsh) is a key scaffold protein that propagates Wnt signaling essential for embryogenesis and homeostasis. However, whether the antagonism of…”
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Author Correction: Sclerostin inhibits Wnt signaling through tandem interaction with two LRP6 ectodomains by Kim, Jinuk, Han, Wonhee, Park, Taeyong, Kim, Eun Jin, Bang, Injin, Lee, Hyun Sik, Jeong, Yejin, Roh, Kyeonghwan, Kim, Jeesoo, Kim, Jong-Seo, Kang, Chanhee, Seok, Chaok, Han, Jin-Kwan, Choi, Hee-Jung

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Comparative lipidomic profiling of the human commensal bacterium Propionibacterium acnes and its extracellular vesicles by Jeon, Jinseong, Park, Seung Cheol, Her, Jin, Lee, Jae Won, Han, Jin-Kwan, Kim, Yoon-Keun, Kim, Kwang Pyo, Ban, Changill

“…is a lipophilic commensal bacterium mainly found on the skin and in the gastrointestinal tract. Pathophysiological effects of have recently been reported not…”
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Proteomic analysis of extracellular vesicles derived from Propionibacterium acnes by Jeon, Jinseong, Mok, Hyuck Jun, Choi, Youngwoo, Park, Seung Cheol, Jo, Hunho, Her, Jin, Han, Jin‐Kwan, Kim, Yoon‐Keun, Kim, Kwang Pyo, Ban, Changill

“…Purpose Extracellular vesicle (EV) has been reported to conduct critical pathophysiological functions as an emerging mode of communication in bacteria…”
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Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels by Chae, Soomin, Lee, Hyun-Kyung, Kim, Yoo-Kyung, Jung Sim, Hyo, Ji, Yoorim, Kim, Chowon, Ismail, Tayaba, Park, Jeen-Woo, Kwon, Oh-Shin, Kang, Beom-Sik, Lee, Dong-Seok, Bae, Jong-Sup, Kim, Sang-Hyun, Min, Kyoung-Jin, Kyu Kwon, Taeg, Park, Mae-Ja, Han, Jin-Kwan, Kwon, Taejoon, Park, Tae-Joo, Lee, Hyun-Shik

“…Peroxiredoxin1 (Prdx1) is an antioxidant enzyme belonging to the peroxiredoxin family of proteins. Prdx1 catalyzes the reduction of H 2 O 2 and alkyl…”
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Role of Sp5 as an essential early regulator of neural crest specification in xenopus by Park, Dong‐Seok, Seo, Jeong‐Han, Hong, Mina, Bang, Wonseon, Han, Jin‐Kwan, Choi, Sun‐Cheol

“…Background: The neural crest (NC) is a multipotent embryonic cell population, which is induced by an integration of secreted signals including BMP, Wnt, and…”
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Essential role for β-arrestin 2 in the regulation of Xenopus convergent extension movements by Kim, Gun-Hwa, Han, Jin-Kwan

“…β‐Arrestin 2 (βarr2) is a multifunctional protein that regulates numerous aspects of G‐protein‐coupled receptor function. However, its possible involvement in…”
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Dual functions of DP1 promote biphasic Wnt-on and Wnt-off states during anteroposterior neural patterning by Kim, Wan-tae, Kim, Hyunjoon, Katanaev, Vladimir L, Joon Lee, Seung, Ishitani, Tohru, Cha, Boksik, Han, Jin-Kwan, Jho, Eek-hoon

“…DP1, a dimerization partner protein of the transcription factor E2F, is known to inhibit Wnt/β‐catenin signalling along with E2F, although the function of DP1…”
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Interactions between Transmembrane Helices within Monomers of the Aquaporin AtPIP2;1 Play a Crucial Role in Tetramer Formation by Yoo, Yun-Joo, Lee, Hyun Kyung, Han, Wonhee, Kim, Dae Heon, Lee, Myoung Hui, Jeon, Jouhyun, Lee, Dong Wook, Lee, Junho, Lee, Yongjik, Lee, Juhun, Kim, Jin Seok, Cho, Yunje, Han, Jin-Kwan, Hwang, Inhwan

“…Aquaporin （AQP） is a water channel protein found in various subcellular membranes of both prokaryotic and eukaryotic cells. The physiological functions of AQPs…”
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Meteorin regulates mesendoderm development by enhancing nodal expression by Kim, Yoon-Young, Moon, Jin-Sook, Kwon, Min-chul, Shin, Juhee, Im, Sun-Kyoung, Kim, Hyun-A, Han, Jin-Kwan, Kong, Young-Yun

“…During gastrulation, distinct lineage specification into three germ layers, the mesoderm, endoderm and ectoderm, occurs through an elaborate harmony between…”
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JNK and ROKα function in the noncanonical Wnt/RhoA signaling pathway to regulate Xenopus convergent extension movements by Kim, Gun‐Hwa, Han, Jin‐Kwan

“…The Wnt/planar cell polarity (PCP) pathway plays a critical role in wing, eye, and sensory bristle development of Drosophila and in convergent extension (CE)…”
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Rab3d is required for Xenopus anterior neurulation by regulating noggin secretion by Kim, Hyunjoon, Han, Jin‐Kwan

“…Rab3d is a member of the Ras‐related small GTPase family of secretory Rab, Rab3. In this study, we showed that Xenopus Rab3d is expressed specifically in the…”
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Dab2 is pivotal for endothelial cell migration by mediating VEGF expression in cancer cells by Cheong, Seong-Moon, Choi, Hyemin, Hong, Bok Sil, Gho, Yong Song, Han, Jin-Kwan

“…Although angiogenesis is crucial for tumor growth and metastasis, the molecular mechanisms controlling this process are not clearly understood. Here, we…”
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