Search Results - "Han, Haozhen"

Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5 by Han, Haozhen, Li, Chunpu, Li, Man, Yang, Lisheng, Zhao, Sen, Wang, Zhifei, Liu, Hong, Liu, Dongxiang

“…Sirtuins (SIRT1-7) are a family of NAD+-dependent deacetylases. They regulate many physiological processes and play important roles in inflammation, diabetes,…”
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Discovery of 5‑Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors by Li, Chunpu, Hu, Sha-Sha, Yang, Lisheng, Wang, Min, Long, Jian-Dong, Wang, Bing, Han, Haozhen, Zhu, Haoran, Zhao, Sen, Liu, Jing-Gen, Liu, Dongxiang, Liu, Hong

“…SIRT1, a member of the sirtuin family, catalyzes the deacetylation of proteins with the transformation of NAD+ into nicotinamide and 2′-O-acetyl-ADP-ribose…”
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Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1 H -Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5 by Han, Haozhen, Li, Chunpu, Li, Man, Yang, Lisheng, Zhao, Sen, Wang, Zhifei, Liu, Hong, Liu, Dongxiang

“…Sirtuins (SIRT1-7) are a family of NAD -dependent deacetylases. They regulate many physiological processes and play important roles in inflammation, diabetes,…”
Get full text