Search Results - "Han, Haote"

Chalcomoracin is a potent anticancer agent acting through triggering Oxidative stress via a mitophagy- and paraptosis-dependent mechanism by Han, Haote, Chou, Chih-Chien, Li, Ruyi, Liu, Jiangyun, Zhang, Lin, Zhu, Wei, Hu, Jin, Yang, Bingxian, Tian, Jingkui

“…Chalocomoracin (CMR), one of the major secondary metabolites found in fungus-infected mulberry leaves, is a potent anticancer agent. However, its anticancer…”
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Capilliposide B blocks VEGF-induced angiogenesis in vitro in primary human retinal microvascular endothelial cells by Han, Haote, Yang, Yanhui, Wu, Zhipan, Liu, Bing, Dong, Lijun, Deng, Hongwei, Tian, Jingkui, Lei, Hetian

“…Abnormal angiogenesis is associated with intraocular diseases such as proliferative diabetic retinopathy and neovascular age-related macular degeneration, and…”
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Phosphoproteomics Reveals Regulation of Secondary Metabolites in Mahonia bealei Exposed to Ultraviolet-B Radiation by Liu, Amin, Liu, Shengzhi, Li, Yaohan, Tao, Minglei, Han, Haote, Zhong, Zhuoheng, Zhu, Wei, Tian, Jingkui

“…Mahonia bealei (M. bealei) is a traditional Chinese medicine containing a high alkaloid content used to treat various diseases. Generally, only dried root and…”
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A Novel Benzofuran Derivative Moracin N Induces Autophagy and Apoptosis Through ROS Generation in Lung Cancer by Gao, Chengcheng, Sun, Xin, Wu, Zhipan, Yuan, Huahua, Han, Haote, Huang, Hongliang, Shu, Yuhan, Xu, Mengting, Gao, Ruilan, Li, Shouxin, Zhang, Jianbin, Tian, Jingkui

“…The leaves of is a traditional Chinese medicine widely applied in lung diseases. Moracin N (MAN), a secondary metabolite extracted form the leaves of L, is a…”
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Hypoglycemic and hypolipidemic effects of sugar beet (Beta vulgaris L.) extract on C57BL/KsJ db/db mice by Wu, Zhipan, Gong, Haitao, Shen, Yuhang, Han, Haote, Zhu, Wei, Tian, Jingkui, Fan, Hua, Li, Shouxin

“…Sugar beet ( Beta vulgaris L. (BV)) is one of the most important economic crops. The purpose of this study was to examine the effects and mechanism of BV on…”
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Leverage of nuclease-deficient CasX for preventing pathological angiogenesis by Han, Haote, Yang, Yanhui, Jiao, Yunjuan, Qi, Hui, Han, Zhuo, Wang, Luping, Dong, Lijun, Tian, Jingkui, Vanhaesebroeck, Bart, Li, Xiaopeng, Liu, Junwen, Ma, Gaoen, Lei, Hetian

“…Gene editing with a CRISPR/Cas system is a novel potential strategy for treating human diseases. Pharmacological inhibition of phosphoinositide 3-kinase (PI3K)…”
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A Prognostic Signature Constructed by CTHRC1 and LRFN4 in Stomach Adenocarcinoma by Han, Songling, Zhu, Wei, Yang, Weili, Guan, Qijie, Chen, Chao, He, Qiang, Zhong, Zhuoheng, Zhao, Ruoke, Xiong, Hangming, Han, Haote, Li, Yaohan, Sun, Zijian, Hu, Xingjiang, Tian, Jingkui

“…Stomach adenocarcinoma (STAD) is the most common histological type of stomach cancer, which causes a considerable number of deaths worldwide. This study aimed…”
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DHOK Exerts Anti-Cancer Effect Through Autophagy Inhibition in Colorectal Cancer by Shu, Yuhan, Sun, Xin, Ye, Guiqin, Xu, Mengting, Wu, Zhipan, Wu, Caixia, Li, Shouxin, Tian, Jingkui, Han, Haote, Zhang, Jianbin

“…DHOK (14,15β-dihydroxyklaineanone) is a novel diterpene isolated from roots of , a traditional herb widely applied in Southeast Asia. It is reported that DHOK…”
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NFκB-Mediated Expression of Phosphoinositide 3-Kinase δ Is Critical for Mesenchymal Transition in Retinal Pigment Epithelial Cells by Han, Haote, Yang, Yanhui, Han, Zhuo, Wang, Luping, Dong, Lijun, Qi, Hui, Liu, Bing, Tian, Jingkui, Vanhaesebroeck, Bart, Kazlauskas, Andrius, Zhang, Guoming, Zhang, Shaochong, Lei, Hetian

“…Epithelial mesenchymal transition (EMT) plays a vital role in a variety of human diseases including proliferative vitreoretinopathy (PVR), in which retinal…”
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Comparative Proteomic and Metabolomic Analyses of Plasma Reveal the Novel Biomarker Panels for Thyroid Dysfunction by Xia, Haodong, Li, Yaohan, Liu, Shengzhi, Han, Haote, Zhou, Chaoting, Wang, Luyang, Jing, Qiangan, Tian, Jingkui, Tong, Xiangmin, Wang, Ying, Zhu, Wei

“…Thyroid dysfunction, including hypothyroidism (THO) and hyperthyroidism (THE), commonly arise from pathological processes in the thyroid gland. The current…”
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Hydrolysis product of Nigella A obtained from Nigella glandulifera Freyn seeds promotes apoptosis and AMPK-mediated autophagy in human colon cancer SW620 cells by Chen, Lili, Han, Haote, Amin, Awais, Zhang, Lin, Ma, Shenglin

“…Nigella B (NB) is the hydrolysis product of Nigella A (NA), which is extracted from the seeds of Nigella glandulifera Freyn. NB has several beneficial…”
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Analgesic and antiinflammatory activities of the capilliposide derived from Lysimachia capillipes Hemsl., a traditional Chinese medicinal herb by Wu, Zhipan, Han, Haote, Xu, Mengting, Shen, Yuhang, Gao, Chengcheng, Yuan, Huahua, Li, Shouxin, Ye, He, Tian, Jingkui

“…Pain and inflammation are associated with the pathophysiology of different clinical conditions. The Lysimachia capillipes Hemsl. capilliposide (LCc) is the…”
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Promotion of cytoplasmic vacuolation-mediated cell death of human prostate cancer PC-3 cells by oxidative stress induced by daucusol, a new guaiane-type sesquiterpenoid from Daucus carota L by Han, Haote, Liu, Na, Zhang, Lin, Gong, Minghua, Cao, Ming, Li, Baoguo, Kaisa, Sulaiman, Yu, Xiuying, Tian, Jingkui

“…We investigated the antitumor activity of daucusol (DS) derived from Daucus carota L. in PC-3, A549 and HeLa cell lines by the MTT assay. Optical microscopy…”
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Scalable Drug-Mimicking Nanoplasmonic Therapy for Bradyarrhythmia in Cardiomyocytes by Xu, Dongxin, Lyu, Xuelian, Han, Haote, Fang, Jiaru, Xue, Jiajin, Zheng, Jilin, Hu, Ning, Gao, Zhigang

“…Bradyarrhythmia poses a serious threat to human health, with chronic progression causing heart failure and acute onset leading to sudden death. In this study,…”
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Phosphoinositide 3-kinase δ inactivation prevents vitreous-induced activation of AKT/MDM2/p53 and migration of retinal pigment epithelial cells by Han, Haote, Chen, Na, Huang, Xionggao, Liu, Bing, Tian, Jingkui, Lei, Hetian

“…Phosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases that play a critical role in transmitting signals from cell-surface molecules to intracellular…”
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A smart tablet-phone-based high-performance pancreatic cancer cell biosensing system for drug screening by Wang, Qiang, Liang, Tao, Yang, Wenjian, Xu, Youjian, Qin, Chunlian, Han, Haote, Zhou, Xiyang, Wang, Yingwei, Wang, Zhen, Hu, Ning

“…Exploring more efficient pancreatic cancer drug screening platforms is of significant importance for accelerating the drug development process. In this study,…”
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Mitochondrial proteomic analysis reveals the regulation of energy metabolism and reactive oxygen species production in Clematis terniflora DC. leaves under high-level UV-B radiation followed by dark treatment by Tao, Minglei, Zhu, Wei, Han, Haote, Liu, Shengzhi, Liu, Amin, Li, Shouxin, Fu, Hongwei, Tian, Jingkui

“…Clematis terniflora DC. is an important medicinal plant from the family Ranunculaceae. A previous study has shown that active ingredients in C. terniflora,…”
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Dynamic and Label-Free Sensing of Cardiomyocyte Responses to Nanosized Vesicles for Cardiac Oxidative Stress Injury Therapy by Qin, Chunlian, Xu, Dongxin, Han, Haote, Fang, Jiaru, Wang, Hao, Liu, Yingjia, Wang, Haobo, Zhou, Xin, Li, Danyang, Ying, Yibin, Hu, Ning, Xu, Lizhou

“…Cardiac oxidative stress is a significant phenotype of myocardial infarction disease, a leading cause of global health threat. There is an urgent need to…”
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Capilliposide B inhibits the migration of prostate cancer by inducing autophagy through the ROS/AMPK/mTOR pathway by Wang, Luping, Han, Haote, Feng, Yue, Ma, Jiahui, Han, Zhuo, Li, Ruyi, Zhu, Wei, Li, Shouxin, Tian, Jingkui, Zhang, Lin

“…Capilliposide B (CPS‐B), a novel oleanane triterpenoid saponin derived from Lysimachia capillipes Hemsl, is a potent anticancer agent. However, its anticancer…”
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Energy stress induced cardiac autophagy detection via a chronic and dynamic cardiomyocytes-based biosensing platform by He, Cheng-Wen, Shi, Keda, Liang, Tao, Han, Haote, Chen, Liang, Guo, Xiaohuan, Chen, Jie, Li, Kaiqiang, Hao, Ke, Cai, Yuqun, Hu, Ning, Wang, Zhen

“…Hypoglycemia is a common complication which occurs during the treatment of diabetes, closely associated with cardiovascular events. A sudden decrease in blood…”
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