Search Results - "Han, Grace Y. Q."
-
1
RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells
Published in Nature communications (21-04-2023)“…Tissue homeostasis is maintained after stress by engaging and activating the hematopoietic stem and progenitor compartments in the blood. Hematopoietic stem…”
Get full text
Journal Article -
2
Ecological and evolutionary dynamics to design and improve ovarian cancer treatment
Published in Clinical and translational medicine (01-09-2024)“…Ovarian cancer ecosystems are exceedingly complex, consisting of a high heterogeneity of cancer cells. Development of drugs such as poly ADP‐ribose polymerase…”
Get full text
Journal Article -
3
Non-platelet-derived CXCL4 differentially regulates cytotoxic and regulatory T cells through CXCR3 to suppress the immune response to colon cancer
Published in Cancer letters (28-02-2019)“…CXCL4 is mainly produced by activated platelets, and certain somatic cells and cancer cells also express CXCL4. However, the physiological function of…”
Get full text
Journal Article -
4
Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells
Published in Cancer cell (10-04-2023)“…Acute myeloid leukemia (AML) is a hematologic malignancy for which several epigenetic regulators have been identified as therapeutic targets. Here we report…”
Get full text
Journal Article