Search Results - "Han, Esther"

Genome mining for new enediyne antibiotics by Han, Esther J., Seyedsayamdost, Mohammad R.

“…Enediyne antibiotics epitomize nature's chemical creativity. They contain intricate molecular architectures that are coupled with potent biological activities…”
Get full text

Momomycin, an Antiproliferative Cryptic Metabolite from the Oxytetracycline Producer Streptomyces rimosus by Li, Yuchen, Lee, Seoung Rak, Han, Esther J., Seyedsayamdost, Mohammad R.

“…Natural products provide an important source of pharmaceuticals and chemical tools. Traditionally, assessment of unexplored microbial phyla has led to new…”
Get full text

Targeted Discovery of Cryptic Metabolites with Antiproliferative Activity by Han, Esther J., Lee, Seoung Rak, Hoshino, Shotaro, Seyedsayamdost, Mohammad R.

“…Microorganisms have provided a rich source of therapeutically valuable natural products. Recent advances in whole genome sequencing and bioinformatics have…”
Get full text

Targeted Discovery of Cryptic Enediyne Natural Products via FRET-Coupled High-Throughput Elicitor Screening by Han, Esther J., Lee, Seoung Rak, Townsend, Craig A., Seyedsayamdost, Mohammad R.

“…Enediyne antibiotics are a striking family of DNA-cleaving natural products with high degrees of cytotoxicity and structural complexity. Microbial genome…”
Get full text

Hirocidins, Cytotoxic Metabolites from Streptomyces hiroshimensis, Induce Mitochondrion‐Mediated Apoptosis by Han, Esther J., Jeong, Myungeun, Lee, Seoung Rak, Sorensen, Erik J., Seyedsayamdost, Mohammad R.

“…Recent advances in whole genome sequencing have revealed an immense microbial potential for the production of therapeutic small molecules, even from well‐known…”
Get full text

N–Cα Bond Cleavage Catalyzed by a Multinuclear Iron Oxygenase from a Divergent Methanobactin-like RiPP Gene Cluster by Chioti, Vasiliki T., Clark, Kenzie A., Ganley, Jack G., Han, Esther J., Seyedsayamdost, Mohammad R.

“…DUF692 multinuclear iron oxygenases (MNIOs) are an emerging family of tailoring enzymes involved in the biosynthesis of ribosomally synthesized and…”
Get full text

Structural Elucidation of Cryptic Algaecides in Marine Algal‐Bacterial Symbioses by NMR Spectroscopy and MicroED by Park, Jong‐Duk, Li, Yuchen, Moon, Kyuho, Han, Esther J., Lee, Seoung Rak, Seyedsayamdost, Mohammad R.

“…Microbial secondary metabolite discovery is often conducted in pure monocultures. In a natural setting, however, where metabolites are constantly exchanged,…”
Get full text

A Systematic Review of Validity Evidence for the Fundamentals of Laparoscopic Surgery Examination in Gynecology by Lerner, Veronica, DeStephano, Christopher, Ulrich, Amanda, Han, Esther S., LeClaire, Edgar, Chen, Chi Chiung Grace

“…The Fundamentals in Laparoscopic Surgery (FLS) examination is designed to test laparoscopic surgery skills. Our aim for this systematic review was to examine…”
Get full text

Robotic Surgery: Advancements and Inflection Points in the Field of Gynecology by Han, Esther S, Advincula, Arnold P

Get full text

Microphysiological Analysis Platform of Pancreatic Islet β‐Cell Spheroids by Lee, Sang Hun, Hong, SoonGweon, Song, Jihwan, Cho, Byungrae, Han, Esther J., Kondapavulur, Sravani, Kim, Dongchoul, Lee, Luke P.

“…The hallmarks of diabetics are insufficient secretion of insulin and dysregulation of glucagon. It is critical to understand release mechanisms of insulin,…”
Get full text

Microphysiological Analysis Platform of Pancreatic Islet [beta]-Cell Spheroids by Lee, Sang Hun, Hong, SoonGweon, Song, Jihwan, Cho, Byungrae, Han, Esther J, Kondapavulur, Sravani, Kim, Dongchoul, Lee, Luke P

“…The hallmarks of diabetics are insufficient secretion of insulin and dysregulation of glucagon. It is critical to understand release mechanisms of insulin,…”
Get full text

Where Have All the Emergencies Gone? The Impact of the COVID-19 Pandemic on Obstetric and Gynecologic Procedures and Consults at a New York City Hospital by Spurlin, Emily E., Han, Esther S., Silver, Elisabeth R., May, Benjamin L., Tatonetti, Nicholas P., Ingram, Myles A., Jin, Zhezhen, Hur, Chin, Advincula, Arnold P., Hur, Hye-Chun

“…The purpose of this study was to assess the impact of the coronavirus disease 2019 (COVID-19) pandemic on surgical volume and emergency department (ED)…”
Get full text

Current best practice management of interstitial cystitis/bladder pain syndrome by Han, Esther, Nguyen, Laura, Sirls, Larry, Peters, Kenneth

“…Introduction: Over the last 100 years, the terminology and diagnosis criteria for interstitial cystitis have evolved. Many therapeutic options have changed,…”
Get full text

Comparing Surgical Experience and Skill Using a High-Fidelity, Total Laparoscopic Hysterectomy Model by Arora, Chetna, Menzies, Anya, Han, Esther S., Lee, Minyi, Lauer, Jacob K., Hur, Hye-Chun, Kim, Jin Hee, Advincula, Arnold P.

“…OBJECTIVE:To evaluate differences in standardized scores and surgical confidence in the completion of a standardized total laparoscopic hysterectomy and…”
Get full text

Safety in Minimally Invasive Surgery by Han, Esther S., MD, MPH, Advincula, Arnold P., MD

“…Conventional and robot-assisted laparoscopic gynecologic surgery offers many advantages over a traditional laparotomy. However, these minimally invasive…”
Get full text

Hirocidins, Cytotoxic Metabolites from Streptomyces hiroshimensis, Induce Mitochondrion‐Mediated Apoptosis by Han, Esther J., Jeong, Myungeun, Lee, Seoung Rak, Sorensen, Erik J., Seyedsayamdost, Mohammad R.

“…Recent advances in whole genome sequencing have revealed an immense microbial potential for the production of therapeutic small molecules, even from well‐known…”
Get full text

Increasing incidence of bilateral mastectomies: the patient perspective by Han, Esther, M.D, Johnson, Nathalie, M.D, Glissmeyer, Margaret, P.A.–C, Wagie, Terry, R.N., M.S, Carey, Bethany, M.P.H, DelaMelena, Tammy, M.D, Nelson, Joanne, M.D

“…Abstract Background Numerous studies have reported increasing rates of contralateral prophylactic mastectomies (CPMs). Understanding patient rationale for the…”
Get full text

The sticky business of adhesion prevention in minimally invasive gynecologic surgery by Han, Esther S, Scheib, Stacey A, Patzkowsky, Kristin E, Simpson, Khara, Wang, Karen C

“…The negative impact of postoperative adhesions has long been recognized, but available options for prevention remain limited. Minimally invasive surgery is…”
Get full text

Momomycin, an Antiproliferative Cryptic Metabolite from the Oxytetracycline Producer Streptomyces rimosus by Li, Yuchen, Lee, Seoung Rak, Han, Esther J., Seyedsayamdost, Mohammad R.

“…Natural products provide an important source of pharmaceuticals and chemical tools. Traditionally, assessment of unexplored microbial phyla has led to new…”
Get full text

Optimizing surgical management of patients who decline blood transfusion by Han, Esther S, Arora, Chetna, Hur, Hye-Chun, Advincula, Arnold P, Kim, Jin Hee J

“…This review highlights the complexity of caring for gynecologic patients who refuse blood transfusion and discusses the importance of early, targeted…”
Get full text