Search Results - "Han, Donghe"
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Pharmacological effects of salidroside on central nervous system diseases
Published in Biomedicine & pharmacotherapy (01-12-2022)“…Salidroside (SAL) is a phenylpropanoid glycoside monomer extracted from Rhodiola at high altitudes. It has been proven to have protective effects on myocardial…”
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2
VEGF inhibits the inflammation in spinal cord injury through activation of autophagy
Published in Biochemical and biophysical research communications (21-08-2015)“…Vascular endothelial growth factor (VEGF) is a secreted mitogen associated with angiogenesis and re-vascularization of spinal cord injury (SCI). VEGF has long…”
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3
Performance Analysis of New One-Piece Iron Roughneck and Its Spinning Mechanism
Published in Machines (Basel) (01-08-2024)“…The iron roughneck is an automated piece of equipment utilized for the connection and removal of drilling tools. This paper presents the design of an…”
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New insights into the role of Klotho in inflammation and fibrosis: molecular and cellular mechanisms
Published in Frontiers in immunology (06-09-2024)“…As the body's defense mechanism against damage and infection, the inflammatory response is a pathological process that involves a range of inflammatory cells…”
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Klotho ameliorates cyclosporine A–induced nephropathy via PDLIM2/NF-kB p65 signaling pathway
Published in Biochemical and biophysical research communications (29-04-2017)“…Klotho, an antiaging protein, can extend the lifespan and modulate cellular responses to inflammation and oxidative stress which can ameliorate chronic kidney…”
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Cytoprotective Effect of Taurine against Hydrogen Peroxide-Induced Oxidative Stress in UMR-106 Cells through the Wnt/β-Catenin Signaling Pathway
Published in Biomolecules & therapeutics (01-11-2018)“…Osteoporosis development is closely associated with oxidative stress and reactive oxygen species (ROS). Taurine has potential antioxidant effects, but its role…”
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Cytoprotective Effect of Taurine against Hydrogen Peroxide- Induced Oxidative Stress in UMR-106 Cells through the Wnt/β- Catenin Signaling Pathway
Published in Biomolecules & therapeutics (01-11-2018)“…Osteoporosis development is closely associated with oxidative stress and reactive oxygen species (ROS). Taurine has potential antioxidant effects, but its role…”
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Simvastatin inhibits neural cell apoptosis and promotes locomotor recovery via activation of Wnt/β‐catenin signaling pathway after spinal cord injury
Published in Journal of neurochemistry (01-07-2016)“…Statins exhibit neuroprotective effects after spinal cord injury (SCI). However, the molecular mechanism underlying these effects remains unknown. This study…”
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Effects of Sirtuin 1 on microglia in spinal cord injury: involvement of Wnt/β-catenin signaling pathway
Published in Neuroreport (04-09-2019)“…Because posttraumatic inflammation contributes to the progression of neuron degeneration, attenuating inflammation is important for reducing neural…”
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Neuroprotection by nicotinamide mononucleotide adenylyltransferase 1 with involvement of autophagy in an aged rat model of transient cerebral ischemia and reperfusion
Published in Brain research (15-11-2019)“…[Display omitted] •The expression of NMNAT1 is increased in the peri-infarct penumbra of aged rats.•Overexpression of NMNAT1 is neuroprotective in aged…”
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Effect of Sirtuin-1 and Wnt/β-Catenin Signaling Pathway in Rat Model of Spinal Cord Injury
Published in Computational and mathematical methods in medicine (27-03-2022)“…Sirtuin-1 (SIRT1) has anti-inflammatory and antioxidant effects and has been reported to be involved in spinal cord injury (SCI). Wnt/β-catenin signal has been…”
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Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin promotes inflammation in mouse testes: The critical role of Klotho in Sertoli cells
Published in Toxicology letters (01-10-2018)“…•The maternal exposure to TCDD increases testis susceptibility to infection.•TCDD inhibits expression of Klotho and PDLIM2.•The downregulated Klotho by TCDD…”
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Nicotinamide Mononucleotide Adenylyltransferase 1 Protects Neural Cells Against Ischemic Injury in Primary Cultured Neuronal Cells and Mouse Brain with Ischemic Stroke Through AMP-Activated Protein Kinase Activation
Published in Neurochemical research (01-06-2015)“…Nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1) is a nicotinamide adenine dinucleotide biosynthetic enzyme. It has been shown to be neuroprotective…”
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Antioxidant and Immunomodulatory Activities of Essential Oil Isolated from Anti-Upper Respiratory Tract Infection Formulation and Their Chemical Analysis
Published in Evidence-based complementary and alternative medicine (2022)“…This study evaluates the in vitro antioxidant and immunomodulation activities of essential oils isolated from an anti-upper respiratory tract infection (URTI)…”
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Protective effects of aerobic swimming training on high-fat diet induced nonalcoholic fatty liver disease: Regulation of lipid metabolism via PANDER-AKT pathway
Published in Biochemical and biophysical research communications (20-03-2015)“…This study aimed to investigate the mechanism by which aerobic swimming training prevents high-fat-diet-induced nonalcoholic fatty liver disease (NAFLD)…”
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Wnt signaling regulates hepatic metabolism
Published in Science signaling (01-02-2011)“…The contribution of the Wnt pathway has been extensively characterized in embryogenesis, differentiation, and stem cell biology but not in mammalian…”
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Neuroprotective Effect of Simvastatin via Inducing the Autophagy on Spinal Cord Injury in the Rat Model
Published in BioMed research international (01-01-2015)“…Simvastatin, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase, is invariably used to treat cardiovascular diseases. Simvastatin has been…”
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Simvastatin inhibits neural cell apoptosis and promotes locomotor recovery via activation of Wnt/[beta]-catenin signaling pathway after spinal cord injury
Published in Journal of neurochemistry (01-07-2016)“…Statins exhibit neuroprotective effects after spinal cord injury (SCI). However, the molecular mechanism underlying these effects remains unknown. This study…”
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19
The Neuroprotective Effects of Muscle-Derived Stem Cells via Brain-Derived Neurotrophic Factor in Spinal Cord Injury Model
Published in BioMed research international (01-01-2017)“…Muscle-derived stem cells (MDSCs) possess multipotent differentiation and self-renewal capacities; however, the effects and mechanism in neuron injury remain…”
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MP Resulting in Autophagic Cell Death of Microglia through Zinc Changes against Spinal Cord Injury
Published in BioMed research international (01-01-2016)“…Methylprednisolone pulse therapy (MPPT), as a public recognized therapy of spinal cord injury (SCI), is doubted recently, and the exact mechanism of MP on SCI…”
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