Search Results - "Han, Brenda Y"

Global translation during early development depends on the essential transcription factor PRDM10 by Han, Brenda Y., Seah, Michelle K. Y., Brooks, Imogen R., Quek, Delia H. P., Huxley, Dominic R., Foo, Chuan-Sheng, Lee, Li Ting, Wollmann, Heike, Guo, Huili, Messerschmidt, Daniel M., Guccione, Ernesto

“…Members of the PR/SET domain-containing (PRDM) family of zinc finger transcriptional regulators play diverse developmental roles. PRDM10 is a yet…”
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Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response by Theusch, Elizabeth, Ting, Flora Y, Qin, Yuanyuan, Stevens, Kristen, Naidoo, Devesh, King, Sarah M, Yang, Neil V, Orr, Joseph, Han, Brenda Y, Cyster, Jason G, Chen, Yii-Der I, Rotter, Jerome I, Krauss, Ronald M, Medina, Marisa W

“…Statins lower circulating low-density lipoprotein cholesterol (LDLC) levels and reduce cardiovascular disease risk. Though highly efficacious in general, there…”
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Zinc finger protein Zfp335 is required for the formation of the naïve T cell compartment by Han, Brenda Y, Wu, Shuang, Foo, Chuan-Sheng, Horton, Robert M, Jenne, Craig N, Watson, Susan R, Whittle, Belinda, Goodnow, Chris C, Cyster, Jason G

“…The generation of naïve T lymphocytes is critical for immune function yet the mechanisms governing their maturation remain incompletely understood. We have…”
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The KRAB-zinc-finger protein ZFP708 mediates epigenetic repression at RMER19B retrotransposons by Seah, Michelle K Y, Wang, Yaju, Goy, Pierre-Alexis, Loh, Hui Mun, Peh, Wen Jun, Low, Diana H P, Han, Brenda Y, Wong, Esther, Leong, Ei Leen, Wolf, Gernot, Mzoughi, Slim, Wollmann, Heike, Macfarlan, Todd S, Guccione, Ernesto, Messerschmidt, Daniel M

“…Global epigenetic reprogramming is vital to purge germ cell-specific epigenetic features to establish the totipotent state of the embryo. This process…”
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