Search Results - "Hamza, Haya"
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The Immunopathology of COVID-19 and the Cannabis Paradigm
Published in Frontiers in immunology (12-02-2021)“…Coronavirus disease-19 caused by the novel RNA betacoronavirus SARS-CoV2 has first emerged in Wuhan, China in December 2019, and since then developed into a…”
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A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism
Published in Cancer cell (12-08-2013)“…Senescence, perceived as a cancer barrier, is paradoxically associated with inflammation, which promotes tumorigenesis. Here, we characterize a distinct…”
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High-CBD Extract (CBD-X) Downregulates Cytokine Storm Systemically and Locally in Inflamed Lungs
Published in Frontiers in immunology (16-05-2022)“…Cytokine storm refers to the dysregulated production of inflammatory mediators leading to hyperinflammation. They are often detrimental, and worsen the…”
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High-CBD Extract (CBD-X) in Asthma Management: Reducing Th2-Driven Cytokine Secretion and Neutrophil/Eosinophil Activity
Published in Pharmaceuticals (Basel, Switzerland) (17-10-2024)“…Asthma is a chronic inflammatory disorder of the airways affecting over 10% of the global population. It is characterized by airway inflammation, mucus…”
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Physiological and pathological roles of LRRK2 in the nuclear envelope integrity
Published in Human molecular genetics (01-12-2019)“…Abstract Mutations in LRRK2 cause autosomal dominant and sporadic Parkinson’s disease, but the mechanisms involved in LRRK2 toxicity in PD are yet to be fully…”
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Cannabis and Rheumatoid Arthritis: A Scoping Review Evaluating the Benefits, Risks, and Future Research Directions
Published in Rambam Maimonides medical journal (01-10-2023)“…Rheumatoid diseases, including rheumatoid arthritis, osteoarthritis, and fibromyalgia, are characterized by progressive inflammation in the musculoskeletal…”
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SUMOylation and ubiquitination reciprocally regulate α-synuclein degradation and pathological aggregation
Published in Proceedings of the National Academy of Sciences - PNAS (12-12-2017)“…α-Synuclein accumulation is a pathological hallmark of Parkinson’s disease (PD). Ubiquitinated α-synuclein is targeted to proteasomal or lysosomal degradation…”
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Multi-Frequency RF Combined with Intense Pulsed Light Improves Signs and Symptoms of Dry Eye Disease Due to Meibomian Gland Dysfunction
Published in Clinical ophthalmology (Auckland, N.Z.) (31-10-2023)“…Purpose: To evaluate the efficacy of multi-frequency RF and IPL + MGX combination for treatment of Meibomian Gland Dysfunction (MGD). Patients and Methods:…”
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SIAH proteins regulate the degradation and intra‐mitochondrial aggregation of PINK1: Implications for mitochondrial pathology in Parkinson's disease
Published in Aging cell (01-12-2022)“…Parkinson's disease (PD) is characterized by degeneration of neurons, particularly dopaminergic neurons in the substantia nigra. PD brains show accumulation of…”
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SUMOylation and ubiquitination reciprocally regulate a-synuclein degradation and pathological aggregation
Published in Proceedings of the National Academy of Sciences - PNAS (12-12-2017)“…a-Synuclein accumulation is a pathological hallmark of Parkinson's disease (PD). Ubiquitinated a-synuclein is targeted to proteasomal or lysosomal degradation…”
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A Senescence-Inflammatory Switch from Cancer-Inhibitory to Cancer-Promoting Mechanism
Published in Cancer cell (08-06-2015)Get full text
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S-6 : Parainflammation in cancer
Published in Cytokine (Philadelphia, Pa.) (01-11-2014)“…Inflammation has many faces, most commonly observed as an acute reaction in response to pathogen or another insult, or a chronic phase, accompanying chronic…”
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Multi-Frequency RF Combined with Intense Pulsed Light Improves Signs and Symptoms of Dry Eye Disease Due to Meibomian Gland Dysfunction
Published in Clinical ophthalmology (Auckland, N.Z.) (01-01-2023)“…PurposeTo evaluate the efficacy of multi-frequency RF and IPL + MGX combination for treatment of Meibomian Gland Dysfunction (MGD).Patients and MethodsEligible…”
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