Search Results - "Hampton, K K"
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1
Bedside Ultrasonography in Clinical Education and Practice Survey: Evaluation of a Pilot Educational Intervention for Medical Students
Published in Annals of emergency medicine (01-11-2013)Get full text
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2
Host-pathogen genetic interactions underlie tuberculosis susceptibility in genetically diverse mice
Published in eLife (03-02-2022)“…The outcome of an encounter with ( ) depends on the pathogen's ability to adapt to the variable immune pressures exerted by the host. Understanding this…”
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Fc-mediated pan-sarbecovirus protection after alphavirus vector vaccination
Published in Cell reports (Cambridge) (25-04-2023)“…Group 2B β-coronaviruses (sarbecoviruses) have caused regional and global epidemics in modern history. Here, we evaluate the mechanisms of cross-sarbecovirus…”
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Chronic low back pain comorbidity count and its impact on exacerbating opioid and non‐opioid prescribing behavior
Published in Pain practice (01-03-2023)“…Research Objectives The objective of the study was to determine the characteristics of chronic low back pain (CLBP) comorbidity and its impact on opioid and…”
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Genetic loci regulate Sarbecovirus pathogenesis: A comparison across mice and humans
Published in Virus research (01-06-2024)“…•First, we introduce and describe the feasibility of the CC as a screening platform for complex genetic regulation of SARS-Like group 2B coronaviruses…”
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Perianesthetic mortality in English Bulldogs: a retrospective analysis in 2010 - 2017
Published in BMC veterinary research (25-05-2022)“…Many veterinarians consider English Bulldogs to have a greater perianesthetic mortality risk. The aims of this study were to 1) determine total and…”
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Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis
Published in PLoS genetics (27-12-2022)“…Variation in immune homeostasis, the state in which the immune system is maintained in the absence of stimulation, is highly variable across populations. This…”
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Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross
Published in Cell reports (Cambridge) (28-04-2020)“…Host genetic factors play a fundamental role in regulating humoral immunity to viral infection, including influenza A virus (IAV). Here, we utilize the…”
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panmictic fiddler crab from the coast of Brazil? Impact of divergent ocean currents and larval dispersal potential on genetic and morphological variation in Uca maracoani
Published in Marine biology (2014)“…Marine species tend to exhibit relatively less population structuring than terrestrial species owing to fewer barriers to gene flow and increased connectivity…”
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Modeling Temperature Regime and Physical Habitat Impacts from Restored Streamflow
Published in Environmental management (New York) (01-06-2019)“…Water infrastructure updates at Grand Canyon National Park (GRCA) provide an opportunity to restore natural flow to Bright Angel Creek, adding an additional…”
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First report on the safety and efficacy of an extended half‐life glycoPEGylated recombinant FVIII for major surgery in severe haemophilia A
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-09-2017)“…Background N8‐GP (turoctocog alfa pegol) is an extended half‐life glycoPEGylated recombinant factor VIII (FVIII) product developed for the prevention and…”
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Novel, human cell line-derived recombinant factor VIII (human-cl rhFVIII; Nuwiq®) in adults with severe haemophilia A: efficacy and safety
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-03-2016)“…Introduction Nuwiq® [human cell line‐derived recombinant factor VIII (human‐cl rhFVIII)] is a new generation rFVIII protein, without chemical modification or…”
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Novel platelet membrane glycoprotein VI dimorphism is a risk factor for myocardial infarction
Published in Circulation (New York, N.Y.) (25-09-2001)“…Glycoprotein (GP) VI plays a crucial role in platelet activation and aggregation. We investigated whether polymorphic variation at the GP VI locus confers an…”
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Expression of a Constitutively Active Human Insulin Receptor in Hippocampal Neurons Does Not Alter VGCC Currents
Published in Neurochemical research (01-01-2019)“…Memory and cognitive decline are the product of numerous physiological changes within the aging brain. Multiple theories have focused on the oxidative,…”
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The impact of Xpert® MTB/RIF in sparsely populated rural settings
Published in The international journal of tuberculosis and lung disease (01-04-2015)“…BACKGROUND: The impact of implementing Xpert® MTB/RIF and the choice of instrument placement on patient care in sparsely populated areas with poor access to…”
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Pathways driving the endocytosis of mutant and wild-type EGFR in cancer
Published in Oncoscience (29-07-2014)“…EGFR (epidermal growth factor receptor) is activated through changes in expression or mutations in a number of tumors and is a driving force in cancer…”
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TREATMENT BURDEN AND PATIENT PREFERENCE IN PATIENTS WITH HEMOPHILIA A OR B WITH INHIBITORS ON CONCIZUMAB PROPHYLAXIS: RESULTS FROM THE PHASE 3 EXPLORER7 STUDY
Published in Hematology, Transfusion and Cell Therapy (01-10-2023)“…Introduction: Concizumab is a humanised, recombinant monoclonal antibody administered to patients with haemophilia A/B with inhibitors (HAwI/HBwI) as a…”
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Efficacy and safety of Nuwiq® (human‐cl rhFVIII) in patients with severe haemophilia A undergoing surgical procedures
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-01-2018)“…Introduction Haemophilia A patients are at a high risk of excess bleeding during surgeries. The aim of haemostatic therapy during the perioperative period is…”
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Host Genetic Variation Impacts SARS-CoV-2 Vaccination Response in the Diversity Outbred Mouse Population
Published in Vaccines (Basel) (01-01-2024)“…The COVID-19 pandemic led to the rapid and worldwide development of highly effective vaccines against SARS-CoV-2. However, there is significant…”
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Safety and efficacy of BAY 81-8973 for surgery in previously treated patients with haemophilia A: results of the LEOPOLD clinical trial programme
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-05-2016)“…Introduction BAY 81‐8973 is a recombinant factor VIII (rFVIII) with the same amino acid sequence as Bayer's sucrose‐formulated rFVIII (rFVIII‐FS) but…”
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