Search Results - "Hampton, Brian"
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Multi-scale magnetic mapping of serpentinite carbonation
Published in Nature communications (30-11-2017)“…Peridotite carbonation represents a critical step within the long-term carbon cycle by sequestering volatile CO 2 in solid carbonate. This has been proposed as…”
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Sheetflow fluvial processes in a rapidly subsiding basin, Altiplano plateau, Bolivia
Published in Sedimentology (01-10-2007)“…Although facies models of braided, meandering and anastomosing rivers have provided the cornerstones of fluvial sedimentology for several decades, the…”
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Regulator of Cell Cycle Protein (RGCC/RGC-32) Protects against Pulmonary Fibrosis
Published in American journal of respiratory cell and molecular biology (01-02-2022)“…Some previous studies in tissue fibrosis have suggested a profibrotic contribution from elevated expression of a protein termed either RGCC (regulator of cell…”
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LRP1 (Low-Density Lipoprotein Receptor–Related Protein 1) Regulates Smooth Muscle Contractility by Modulating Ca2+ Signaling and Expression of Cytoskeleton-Related Proteins
Published in Arteriosclerosis, thrombosis, and vascular biology (01-11-2018)“…OBJECTIVE—Mutations affecting contractile-related proteins in the ECM (extracellular matrix), microfibrils, or vascular smooth muscle cells can predispose the…”
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Leveraging Surface Plasmon Resonance to Dissect the Interfacial Properties of Nanoparticles: Implications for Tissue Binding and Tumor Penetration
Published in Nanomedicine (01-08-2019)“…Therapeutic efficacy of nanoparticle-drug formulations for cancer applications is significantly impacted by the extent of intra-tumoral accumulation and tumor…”
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LRP1 Protects the Vasculature by Regulating Levels of Connective Tissue Growth Factor and HtrA1
Published in Arteriosclerosis, thrombosis, and vascular biology (01-09-2013)“…OBJECTIVE—Low-density lipoprotein receptor–related protein 1 (LRP1) is a large endocytic and signaling receptor that is abundant in vascular smooth muscle…”
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Detrital zircons and sediment dispersal in the eastern Midcontinent of North America
Published in Geosphere (Boulder, Colo.) (01-06-2020)“…Results of detrital-zircon analyses (U-Pb ages and initial Hf values, εHft) of Mississippian-Pennsylvanian sandstones in the Michigan, Illinois, and Forest…”
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The full-length interleukin-33 (FLIL33)–importin-5 interaction does not regulate nuclear localization of FLIL33 but controls its intracellular degradation
Published in The Journal of biological chemistry (29-12-2017)“…Human mature IL-33 is a member of the IL-1 family and a potent regulator of immunity through its pro-T helper cell 2 activity. Its precursor form, full-length…”
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Full-length IL-33 regulates Smad3 phosphorylation and gene transcription in a distinctive AP2-dependent manner
Published in Cellular immunology (01-11-2020)“…•Elevated full-length IL-33 induces Smad3 phosphorylation in human lung fibroblasts.•This effect is TGF-β-independent but TGFBR- and adaptor protein complex…”
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LRP1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin II-mediated signaling
Published in JCI insight (24-01-2023)“…Vascular smooth muscle cells (vSMCs) exert a critical role in sensing and maintaining vascular integrity. These cells abundantly express the low-density…”
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A Mediator-Responsive Form of Metazoan RNA Polymerase II
Published in Proceedings of the National Academy of Sciences - PNAS (20-06-2006)“…RNA polymerase II (Pol II), whose 12 subunits are conserved across eukaryotes, is at the heart of the machinery responsible for transcription of mRNA. Although…”
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A detrital record of Mesozoic island arc accretion and exhumation in the North American Cordillera: U-Pb geochronology of the Kahiltna basin, southern Alaska
Published in Tectonics (Washington, D.C.) (01-08-2010)“…The stratigraphic record of Mesozoic arc accretion in the North American Cordillera is preserved in a discontinuous belt of clastic strata that are exposed…”
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A subset of mobilized human hematopoietic stem cells express germ layer lineage genes which can be modulated by culture conditions
Published in Stem cell research & therapy (02-05-2018)“…Adult bone marrow contains stem cells that replenish the myeloid and lymphoid lineages. A subset of human and mouse CD34 bone marrow stem cells can be…”
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The reverse in-gel kinase assay to profile physiological kinase substrates
Published in Nature methods (01-11-2007)“…Elucidating kinase-substrate relationships is critical for understanding how phosphorylation affects signal transduction and regulatory cascades. Using the…”
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Integrin clustering induces kinectin accumulation
Published in Journal of cell science (15-05-2002)“…Integrin receptors mediate the formation of adhesion complexes and play important roles in signal transduction from the extracellular matrix. Integrin-based…”
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S100A13 Is Involved in the Regulation of Fibroblast Growth Factor-1 and p40 Synaptotagmin-1 Release in Vitro
Published in The Journal of biological chemistry (28-08-1998)“…We have previously characterized the release of the signal peptide sequence-less fibroblast growth factor (FGF) prototype, FGF-1, in vitro as a stress-induced…”
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Abstract 292: LRP1 Prevents Aortic And SMA Aneurysms By Modulating Excessive Ang-II Signaling
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2022)“…ObjectivesLRP1 (low-density lipoprotein receptor-related protein 1) is known to contribute to vascular homeostasis and plays a protective role against the…”
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Abstract 546: Investigation Of The Role Of LRP1 Patient Mutations On Abdominal Aortic Aneurysms
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2022)“…LRP1 (low density lipoprotein receptor-related protein 1) is a large endocytic receptor that binds over 100 structurally unrelated ligands. Our lab has…”
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Stimulation of Mitochondrial Respiration by Idebenone in Pro-inflammatory Microglia is Catalyzed by iNOS
Published in Free radical biology & medicine (20-02-2022)Get full text
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