Search Results - "Hammouda, Omar T"

Automated high-throughput heartbeat quantification in medaka and zebrafish embryos under physiological conditions by Gierten, Jakob, Pylatiuk, Christian, Hammouda, Omar T., Schock, Christian, Stegmaier, Johannes, Wittbrodt, Joachim, Gehrig, Jochen, Loosli, Felix

“…Accurate quantification of heartbeats in fish models is an important readout to study cardiovascular biology, disease states and pharmacology. However,…”
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In vivo identification and validation of novel potential predictors for human cardiovascular diseases by Hammouda, Omar T, Wu, Meng Yue, Kaul, Verena, Gierten, Jakob, Thumberger, Thomas, Wittbrodt, Joachim

“…Genetics crucially contributes to cardiovascular diseases (CVDs), the global leading cause of death. Since the majority of CVDs can be prevented by early…”
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Swift Large-scale Examination of Directed Genome Editing by Hammouda, Omar T, Böttger, Frank, Wittbrodt, Joachim, Thumberger, Thomas

“…In the era of CRISPR gene editing and genetic screening, there is an increasing demand for quick and reliable nucleic acid extraction pipelines for rapid…”
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The Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel by Fitzgerald, Tomas, Brettell, Ian, Leger, Adrien, Wolf, Nadeshda, Kusminski, Natalja, Monahan, Jack, Barton, Carl, Herder, Cathrin, Aadepu, Narendar, Gierten, Jakob, Becker, Clara, Hammouda, Omar T, Hasel, Eva, Lischik, Colin, Lust, Katharina, Sokolova, Natalia, Suzuki, Risa, Tsingos, Erika, Tavhelidse, Tinatini, Thumberger, Thomas, Watson, Philip, Welz, Bettina, Khouja, Nadia, Naruse, Kiyoshi, Birney, Ewan, Wittbrodt, Joachim, Loosli, Felix

“…Unraveling the relationship between genetic variation and phenotypic traits remains a fundamental challenge in biology. Mapping variants underlying complex…”
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Genomic variations and epigenomic landscape of the Medaka Inbred Kiyosu-Karlsruhe (MIKK) panel by Leger, Adrien, Brettell, Ian, Monahan, Jack, Barton, Carl, Wolf, Nadeshda, Kusminski, Natalja, Herder, Cathrin, Aadepu, Narendar, Becker, Clara, Gierten, Jakob, Hammouda, Omar T, Hasel, Eva, Lischik, Colin, Lust, Katharina, Sokolova, Natalia, Suzuki, Risa, Tavhelidse, Tinatini, Thumberger, Thomas, Tsingos, Erika, Watson, Philip, Welz, Bettina, Naruse, Kiyoshi, Loosli, Felix, Wittbrodt, Joachim, Birney, Ewan, Fitzgerald, Tomas

“…The teleost medaka (Oryzias latipes) is a well-established vertebrate model system, with a long history of genetic research, and multiple high-quality…”
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CRISPR-based knockout and base editing confirm the role of MYRF in heart development and congenital heart disease by Doering, Lino, Cornean, Alex, Thumberger, Thomas, Benjaminsen, Joergen, Wittbrodt, Beate, Kellner, Tanja, Hammouda, Omar T., Gorenflo, Matthias, Wittbrodt, Joachim, Gierten, Jakob

“…ABSTRACT High-throughput DNA sequencing studies increasingly associate DNA variants with congenital heart disease (CHD). However, functional modeling is a…”
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EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation by Zhang, Chenge, Jin, Yinhua, Marchetti, Marco, Lewis, Mitchell R, Hammouda, Omar T, Edgar, Bruce A

“…EGFR-RAS-ERK signaling promotes growth and proliferation in many cell types, and genetic hyperactivation of RAS-ERK signaling drives many cancers. Yet, despite…”
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