Search Results - "Hammouda, Manel B"
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The JNK Signaling Pathway in Inflammatory Skin Disorders and Cancer
Published in Cells (Basel, Switzerland) (02-04-2020)“…The c-Jun N-terminal kinases (JNKs), with its members JNK1, JNK2, and JNK3, is a subfamily of (MAPK) mitogen-activated protein kinases. JNK signaling regulates…”
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Lebein, a Snake Venom Disintegrin, Induces Apoptosis in Human Melanoma Cells
Published in Toxins (05-07-2016)“…Melanoma, the most threatening form of skin cancer, has a very poor prognosis and is characterized by its very invasive and chemoresistant properties. Despite…”
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Macrovipecetin, a C-type lectin from Macrovipera lebetina venom, inhibits proliferation migration and invasion of SK-MEL-28 human melanoma cells and enhances their sensitivity to cisplatin
Published in Biochimica et biophysica acta. General subjects (01-03-2018)“…The resistance of melanoma cells to cisplatin restricts its clinical use. Therefore, the search for novel tumor inhibitors and effective combination treatments…”
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Promoting E2F1-mediated apoptosis in oestrogen receptor-α-negative breast cancer cells
Published in BMC cancer (26-07-2014)“…Because oestrogen receptor α (ERα) regulates E2F1 expression to mediate tamoxifen resistance in ERα-positive breast cancer cells, we aimed to define the…”
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Promoting E2F1-mediated apoptosis in oestrogen receptor-[alpha]-negative breast cancer cells
Published in BMC cancer (01-01-2014)“…Doc number: 539 Abstract Background: Because oestrogen receptor α (ERα) regulates E2F1 expression to mediate tamoxifen resistance in ERα-positive breast cancer…”
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