Search Results - "Hammoud, Saher S."

Single-Cell Analysis of the Gene Expression Effects of Developmental Lead (Pb) Exposure on the Mouse Hippocampus by Bakulski, Kelly M, Dou, John F, Thompson, Robert C, Lee, Christopher, Middleton, Lauren Y, Perera, Bambarendage P U, Ferris, Sean P, Jones, Tamara R, Neier, Kari, Zhou, Xiang, Sartor, Maureen A, Hammoud, Saher S, Dolinoy, Dana C, Colacino, Justin A

“…Abstract Lead (Pb) exposure is ubiquitous with permanent neurodevelopmental effects. The hippocampus brain region is involved in learning and memory with…”
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Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells by Grill, Sherilyn, Bisht, Kamlesh, Tesmer, Valerie M., Shami, Adrienne Niederriter, Hammoud, Saher S., Nandakumar, Jayakrishnan

“…Telomerase replicates chromosome ends in germ and somatic stem cells to facilitate their continued proliferation. Telomerase action depends on the telomeric…”
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Placental cell type deconvolution reveals that cell proportions drive preeclampsia gene expression differences by Campbell, Kyle A., Colacino, Justin A., Puttabyatappa, Muraly, Dou, John F., Elkin, Elana R., Hammoud, Saher S., Domino, Steven E., Dolinoy, Dana C., Goodrich, Jaclyn M., Loch-Caruso, Rita, Padmanabhan, Vasantha, Bakulski, Kelly M.

“…The placenta mediates adverse pregnancy outcomes, including preeclampsia, which is characterized by gestational hypertension and proteinuria. Placental cell…”
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Obesity-Induced Infertility in Male Mice Is Associated With Disruption of Crisp4 Expression and Sperm Fertilization Capacity by Borges, Beatriz C, Garcia-Galiano, David, da Silveira Cruz-Machado, Sanseray, Han, Xingfa, Gavrilina, Galina B, Saunders, Thomas L, Auchus, Richard J, Hammoud, Saher S, Smith, Gary D, Elias, Carol F

“…Approximately 15% of human couples of reproductive age have impaired fertility, and the male component accounts for about half of these cases. The etiology is…”
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Differential impact of a dyskeratosis congenita mutation in TPP1 on mouse hematopoiesis and germline by Graniel, Jacqueline V, Bisht, Kamlesh, Friedman, Ann, White, James, Perkey, Eric, Vanderbeck, Ashley, Moroz, Alina, Carrington, Léolène J, Brandstadter, Joshua D, Allen, Frederick, Shami, Adrienne Niederriter, Thomas, Peedikayil, Crayton, Aniela, Manzor, Mariel, Mychalowych, Anna, Chase, Jennifer, Hammoud, Saher S, Keegan, Catherine E, Maillard, Ivan, Nandakumar, Jayakrishnan

“…Telomerase extends chromosome ends in somatic and germline stem cells to ensure continued proliferation. Mutations in genes critical for telomerase function…”
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Probabilistic alignment leads to improved accuracy and read coverage for bisulfite sequencing data by Hong, Changjin, Clement, Nathan L, Clement, Spencer, Hammoud, Saher Sue, Carrell, Douglas T, Cairns, Bradley R, Snell, Quinn, Clement, Mark J, Johnson, William Evan

“…DNA methylation has been linked to many important biological phenomena. Researchers have recently begun to sequence bisulfite treated DNA to determine its…”
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