Search Results - "Hammonds, Peter"
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1
Insulin-secreting β-cells possess specific receptors for interleukin-1β
Published in FEBS letters (12-02-1990)“…The effect of the cytokine interleukin-1β on the insulin secretory responsiveness of single β-cells (HIT-T15) was investigated. In the short-term, IL-1β…”
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Journal Article -
2
T-lymphocyte lines specific for glutamic acid decarboxylase (GAD) the 64K β-cell antigen of IDDM
Published in Diabetes (New York, N.Y.) (1992)“…Insulin-dependent diabetes mellitus (IDDM) is viewed as a thymus-dependent autoimmune disease, although the specific beta-cell autoantigen or autoantigens…”
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Journal Article -
3
Effects of environmental temperature on members of the mucorales
Published 01-01-1984“…The following investigation characterises the interaction between temperature and growth in psychrophilic, mesophilic and thermophilic fungi in order to gain…”
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Dissertation -
4
Glucose regulates preproinsulin messenger RNA levels in a clonal cell line of simian virus 40-transformed B cells
Published in FEBS letters (09-03-1987)“…In HIT-T15 cells grown in the absence of glucose, Northern blot analysis of total RNA revealed a major 0.5 kb preproinsulin (ppI) mRNA transcript which…”
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Journal Article -
5
Interleukin-1β inhibits glucokinase activity in clonal HIT-T15 β-cells
Published in FEBS letters (16-07-1990)“…Interleukin-1β (IL-1β) has been implicated in the pathogenesis of insulin-dependent diabetes mellitus. In the present study we have investigated the effects of…”
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Journal Article -
6
Vectorial insulin secretion by pancreatic β-cells
Published in FEBS letters (15-10-1990)“…Morphological studies of pancreatic β-cells have suggested the presence of discrete sensory and secretory domains. In the present study we now provide…”
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Journal Article -
7
Regulation and specificity of glucose-stimulated insulin gene expression in human islets of Langerhans
Published in FEBS letters (19-10-1987)“…The insulin response of cultured human islets of Langerhans was measured at both mRNA and polypeptide levels in response to natural and pharmacological…”
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Journal Article