Search Results - "Hammitzsch, Ariane"

CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses by Hammitzsch, Ariane, Tallant, Cynthia, Fedorov, Oleg, O’Mahony, Alison, Brennan, Paul E., Hay, Duncan A., Martinez, Fernando O., Al-Mossawi, M. Hussein, de Wit, Jelle, Vecellio, Matteo, Wells, Christopher, Wordsworth, Paul, Müller, Susanne, Knapp, Stefan, Bowness, Paul

“…Th17 responses are critical to a variety of human autoimmune diseases, and therapeutic targeting with monoclonal antibodies against IL-17 and IL-23 has shown…”
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Impact of Janus Kinase Inhibition on the Treatment of Axial Spondyloarthropathies by Hammitzsch, Ariane, Lorenz, Georg, Moog, Philipp

“…Many immune cells and effector molecules (e.g. cytokines, Interferons, growth factors) utilize different combinations of Janus kinase (JAK) and signal…”
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Relevance of Grade 1 Gray‐Scale Ultrasound Findings in Wrists and Small Joints to the Assessment of Subclinical Synovitis in Rheumatoid Arthritis by Witt, Matthias, Mueller, Felix, Nigg, Axel, Reindl, Christiane, Leipe, Jan, Proft, Fabian, Stein, Nicola, Hammitzsch, Ariane, Mayer, Stefan, Dechant, Claudia, Schulze‐Koops, Hendrik, Grunke, Mathias

“…Objective To investigate the clinical relevance of grade 1 findings on gray‐scale ultrasound (GSUS) of the joints in patients with rheumatoid arthritis (RA)…”
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Disease burden, disease manifestations and current treatment regimen of the SAPHO syndrome in Germany: Results from a nationwide patient survey by Witt, Matthias, MD, Meier, Johanna, Hammitzsch, Ariane, MD, Proft, Fabian, MD, Schulze-Koops, Hendrik, MD, Grunke, Mathias, MD

“…Abstract Background Due to diagnostic and therapeutic advances, quality of life of patients with spondyloarthritides (SpA) has improved substantially in recent…”
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Increased interleukin-26 in the peripheral joints of patients with axial spondyloarthritis and psoriatic arthritis, co-localizing with CD68-positive synoviocytes by Hammitzsch, Ariane, Ossadnik, Andreas, Bachmann, Quirin, Merwald-Fraenk, Helga, Lorenz, Georg, Witt, Matthias, Wiesent, Franziska, Mühlhofer, Heinrich, Simone, Davide, Bowness, Paul, Heemann, Uwe, Arbogast, Martin, Moog, Philipp, Schmaderer, Christoph

“…levels are elevated in the blood and synovial fluid of patients with inflammatory arthritis. can be produced by Th17 cells and locally within joints by…”
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Evaluation of effectiveness of instruction and study habits in two consecutive clinical semesters of the medical curriculum Munich (MeCuM) reveals the need for more time for self study and higher frequency of assessment by Mueller, Sophia, Weichert, Nina, Stoecklein, Veit, Hammitzsch, Ariane, Pascuito, Giulia, Krug, Christian, Holzer, Matthias, Pfeiffer, Mona, Siebeck, Matthias, Schmidmaier, Ralf

“…Seven years after implementing a new curriculum an evaluation was performed to explore possibilities for improvements. To analyze students' study habits in…”
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Decreased expression of miR-146a and miR-155 contributes to an abnormal Treg phenotype in patients with rheumatoid arthritis by Zhou, Qihui, Haupt, Sonja, Kreuzer, Johannes T, Hammitzsch, Ariane, Proft, Fabian, Neumann, Carla, Leipe, Jan, Witt, Matthias, Schulze-Koops, Hendrik, Skapenko, Alla

“…MicroRNAs (miRNAs) have been implicated in the pathogenesis of autoimmune diseases, not least for their critical role in the regulation of regulatory T cell…”
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Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis by Chen, Liye, Ridley, Anna, Hammitzsch, Ariane, Al-Mossawi, Mohammad Hussein, Bunting, Helen, Georgiadis, Dimitris, Chan, Antoni, Kollnberger, Simon, Bowness, Paul

“…Human leucocyte antigen (HLA)-B27 and endoplasmic reticulum aminopeptidase 1 (ERAP1) are strongly associated with ankylosing spondylitis (AS). ERAP1 is a key…”
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Successful treatment with azacitidine in VEXAS syndrome with prominent myofasciitis by Cordts, Isabell, Hecker, Judith S, Gauck, Darja, Park, Joohyun, Härtl, Johanna, Günthner, Roman, Hammitzsch, Ariane, Schoser, Benedikt, Abeck, Dietrich, Götze, Katharina S, Haack, Tobias B, Deschauer, Marcus, Moog, Philipp, Hemmer, Bernhard

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Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases by Hammitzsch, Ariane, Chen, Liye, de Wit, Jelle, Al-Mossawi, M. Hussein, Ridley, Anna, Sekine, Takuya, Simone, Davide, Doig, Karen, Skapenko, Alla, Bowness, Paul

“…Treatment options for Ankylosing Spondylitis (AS) are still limited. The T helper cell 17 (Th17) pathway has emerged as a major driver of disease pathogenesis…”
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Suppression of DNA-PKcs enhances FGF-2 dependent human endothelial cell proliferation via negative regulation of Akt by Mannell, Hanna, Hammitzsch, Ariane, Mettler, Ramona, Pohl, Ulrich, Krötz, Florian

“…Angiogenesis initiation is crucially dependent on endothelial proliferation and can be stimulated by the fibroblast growth factor 2 (FGF-2). The DNA dependent…”
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Lupus und Nierenbeteiligung by Lorenz, Georg, Heemann, Uwe, Hammitzsch, Ariane

“…Zusammenfassung Hintergrund Der systemische Lupus erythematodes (SLE) und insbesondere die Lupusnephritis (LN) stellen weiterhin eine therapeutische…”
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