Search Results - "Hamming, Kevin S C"

Inhibition of β-Cell Sodium-Calcium Exchange Enhances Glucose-Dependent Elevations in Cytoplasmic Calcium and Insulin Secretion by HAMMING, Kevin S. C, SOLIMAN, Daniel, MACDONALD, Patrick E, LIGHT, Peter E, WEBSTER, Nicola J, SEARLE, Gavin J, MATEMISZ, Laura C, LIKNES, David A, DAI, Xiao-Qing, PULINILKUNNIL, Thomas, RIEDEL, Michael J, DYCK, Jason R. B

“…The sodium-calcium exchanger isoform 1 (NCX1) regulates cytoplasmic calcium (Ca(2+)(c)) required for insulin secretion in beta-cells. NCX1 is alternatively…”
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Splice Variant-Dependent Regulation of β-Cell Sodium-Calcium Exchange by Acyl-Coenzyme As by Hamming, Kevin S. C, Riedel, Michael J, Soliman, Daniel, Matemisz, Laura C, Webster, Nicola J, Searle, Gavin J, MacDonald, Patrick E, Light, Peter E

“…The sodium-calcium exchanger isoform 1 (NCX1) is intimately involved in the regulation of calcium (Ca2+) homeostasis in many tissues including…”
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Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K+ Channel by Hamming, Kevin S C, Soliman, Daniel, Matemisz, Laura C, Niazi, Omid, Lang, Yiqiao, Gloyn, Anna L, Light, Peter E

“…Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive…”
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Late sodium current inhibition alone with ranolazine is sufficient to reduce ischemia- and cardiac glycoside-induced calcium overload and contractile dysfunction mediated by reverse-mode sodium/calcium exchange by Soliman, Daniel, Wang, Lianguo, Hamming, Kevin S C, Yang, Wei, Fatehi, Mohammad, Carter, Christian C, Clanachan, Alexander S, Light, Peter E

“…Excessive reverse-mode (RM) sodium/calcium exchanger 1.1 (NCX1.1) activity, resulting from intracellular sodium accumulation caused by reduced Na+/K+-ATPase…”
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Adrenal Insufficiency: Investigating Prevalence and Healthcare Utilization Using Administrative Data by Sekhon, Sarpreet S, Crick, Katelynn, Myroniuk, Tyler W, Hamming, Kevin S C, Ghosh, Mahua, Campbell-Scherer, Denise, Yeung, Roseanne O

“…Abstract Context Adrenal insufficiency (AI) is an uncommon, life-threatening disorder requiring lifelong treatment with steroid therapy and special attention…”
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Reactive oxygen species directly modify sodium–calcium exchanger activity in a splice variant-dependent manner by Soliman, Daniel, Hamming, Kevin S.C, Matemisz, Laura C, Light, Peter E

“…Abstract The sodium–calcium exchanger isoform 1 (NCX1) operating in calcium-efflux mode plays an important role in maintaining calcium homeostasis in the…”
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Molecular and Functional Characterization of a Family of Rat Brain T-type Calcium Channels by McRory, John E., Santi, Celia M., Hamming, Kevin S.C., Mezeyova, Janette, Sutton, Kathy G., Baillie, David L., Stea, Anthony, Snutch, Terrance P.

“…Voltage-gated calcium channels represent a heterogenous family of calcium-selective channels that can be distinguished by their molecular,…”
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Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E 2 3K and ABCC8 S 1 369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K+ Channel by HAMMING, Kevin S. C, SOLIMAN, Daniel, MATEMISZ, Laura C, NIAZI, Omid, YIQIAO LANG, GLOYN, Anna L, LIGHT, Peter E

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Inhibition of [Beta]-Cell Sodium-Calcium Exchange Enhances Glucose-Dependent Elevations in Cytoplasmic Calcium and Insulin Secretion by Hamming, Kevin S C, Soliman, Daniel, Webster, Nicola J, Searle, Gavin J, Matemisz, Laura C, Liknes, David A, Dai, Xiao-Qing, Pulinilkunnil, Thomas, Riedel, Michael J, Dyck, Jason R B, MacDonald, Patrick E, Light, Peter E

“…The sodium-calcium exchanger isoform 1 (NCX1) regulates cytoplasmic calcium (Ca(2+)(c)) required for insulin secretion in beta-cells. NCX1 is alternatively…”
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Inhibition of reverse‐mode sodium‐calcium exchange by the anti‐anginal agent ranolazine by Soliman, Daniel, Wang, Liango, Hamming, Kevin SC, Matemisz, Laura C, Clanachan, Alexander S, Light, Peter E

“…Myocardial calcium overload observed during ischemia‐reperfusion is largely mediated via reverse mode cardiac sodium‐calcium exchange (NCX1.1), resulting from…”
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