Search Results - "Hammes, H P"

Diabetic retinopathy in type 1 diabetes—a contemporary analysis of 8,784 patients by Hammes, H. P., Kerner, W., Hofer, S., Kordonouri, O., Raile, K., Holl, R. W.

“…Aims/hypothesis The aim of this study was to analyse the risk profile for diabetic retinopathy under real-life conditions in a large cohort of patients with…”
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Pericytes and the pathogenesis of diabetic retinopathy by Hammes, H-P

“…Incipient diabetic retinopathy is characterized by increased vascular permeability and progressive vascular occlusion. Pericyte loss precedes capillary…”
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Carnosine treatment in combination with ACE inhibition in diabetic rats by Peters, V., Riedl, E., Braunagel, M., Höger, S., Hauske, S., Pfister, F., Zschocke, J., Lanthaler, B., Benck, U., Hammes, H.-P., Krämer, B.K., Schmitt, C.P., Yard, B.A., Köppel, H.

“…In humans, we reported an association of a certain allele of carnosinase gene with reduced carnosinase activity and absence of nephropathy in diabetic…”
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Low-dose erythropoietin inhibits oxidative stress and early vascular changes in the experimental diabetic retina by Wang, Q., Pfister, F., Dorn-Beineke, A., vom Hagen, F., Lin, J., Feng, Y., Hammes, H. P.

“…Aims/hypothesis Diabetic retinopathy is the result of increased oxidative and nitrosative stress induced by chronic hyperglycaemia, and affects the vasculature…”
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Dicarbonyl Stress Mimics Diabetic Neurovascular Damage in the Retina by Kolibabka, M, Friedrichs, P, Dietrich, N, Fleming, T, Schlotterer, A, Hammes, H-P

“…The net effect of euglycemic treatment is grossly overestimated in diabetes mellitus and retinopathy, similar to what is observed in diabetic individuals, is…”
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Crosstalk in the retinal neurovascular unit - lessons for the diabetic retina by Feng, Y, Busch, S, Gretz, N, Hoffmann, S, Hammes, H-P

“…Diabetic retinopathy shares important features with neurodegenerative retinal diseases, including loss of ganglion cells and retinal thinning. The impact on…”
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Healthy obese and post bariatric patients - metabolic and vascular patterns by Bachmayer, C, Lammert, A, Hasenberg, T, Hammes, H-P

“…Obesity and the metabolic syndrome (MetS) are associated with endothelial dysfunction (ED). An established method to determine ED is retinal vessel analysis…”
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Protective Effects of Liraglutide and Linagliptin in C. elegans as a New Model for Glucose-Induced Neurodegeneration by Wongchai, K, Schlotterer, A, Lin, J, Humpert, P M, Klein, T, Hammes, H-P, Morcos, M

“…Liraglutide and linagliptin are novel drugs for the treatment of diabetes. Antioxidative and neuroprotective effects have been described for both compounds…”
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SOM230 (pasireotide) and temozolomide achieve sustained control of tumour progression and ACTH secretion in pituitary carcinoma with widespread metastases by Bode, H, Seiz, M, Lammert, A, Brockmann, M A, Back, W, Hammes, H-P, Thomé, C

“…Pituitary carcinomas are rare and neurosurgically challenging lesions, as they commonly relapse after surgical removal. Their prognosis is dismal due to their…”
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Effect of R-(+)-alpha-lipoic acid on experimental diabetic retinopathy by Lin, J, Bierhaus, A, Bugert, P, Dietrich, N, Feng, Y, Vom Hagen, F, Nawroth, P, Brownlee, M, Hammes, H-P

“…Hyperglycaemia-induced mitochondrial overproduction of reactive oxygen species (ROS) is central to the pathogenesis of endothelial damage in diabetes…”
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Zebrafish: a model for understanding diabetic complications by Jörgens, K, Hillebrands, J-L, Hammes, H-P, Kroll, J

“…Diabetes mellitus causes several vascular complications in patients, such as macrovascular problems including myocardial infarction, peripheral artery diseases…”
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Genetics of diabetic retinopathy by Uhlmann, K, Kovacs, P, Boettcher, Y, Hammes, H-P, Paschke, R

“…Familial aggregation as well as racial and ethnic differences in incidence suggest that genetic components play a role in the development of diabetic…”
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Differential accumulation of advanced glycation end products in the course of diabetic retinopathy by HAMMES, H.-P, ALT, A, NIWA, T, CLAUSEN, J. T, BRETZEL, R. G, BROWNLEE, M, SCHLEICHER, E. D

“…Glycated proteins, formed by reaction of glucose and protein, react further yielding numerous, mostly undefined advanced glycation end products (AGE). The…”
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Neuro-endocrine and neuropsychological outcome after aneurysmal subarachnoid hemorrhage (aSAH): a prospective cohort study by Lammert, A, Bode, H, Hammes, H-P, Birck, R, Fatar, M, Zohsel, K, Braun, J, Schmieder, K, Diepers, M, Schubert, G A, Barth, M, Thomé, C, Seiz, M

“…Neuropsychological sequelae are common after aneurysmal subarachnoid hemorrhage (aSAH) and may be associated with or caused by supposed hypothalamic-pituitary…”
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Chronic hyperglycemia inhibits vasoregression in a transgenic model of retinal degeneration by Feng, Y., Wang, Y., Yang, Z., Wu, L., Hoffmann, S., Wieland, T., Gretz, N., Hammes, H.-P.

“…Vasoregression characterizes diabetic retinopathy in animal models and in humans. We have recently demonstrated that vasoregression is earlier initiated in a…”
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Clinical benefit of a short term dietary oatmeal intervention in patients with type 2 diabetes and severe insulin resistance: a pilot study by Lammert, A, Kratzsch, J, Selhorst, J, Humpert, P M, Bierhaus, A, Birck, R, Kusterer, K, Hammes, H-P

“…To evaluate the potential effectiveness of 'carbohydrate days' as a dietary intervention to overcome insulin resistance in type 2 diabetes. Patients (n=14)…”
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Upregulation of the vascular endothelial growth factor/vascular endothelial growth factor receptor system in experimental background diabetic retinopathy of the rat by HAMMES, H.-P, JIHONG LIN, BRETZEL, R. G, BROWNLEE, M, BREIER, G

“…Upregulation of the vascular endothelial growth factor/vascular endothelial growth factor receptor system in experimental background diabetic retinopathy of…”
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ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD by Ryden, L., Grant, P. J., Anker, S. D., Berne, C., Cosentino, F., Danchin, N., Deaton, C., Escaned, J., Hammes, H.-P., Huikuri, H., Marre, M., Marx, N., Mellbin, L., Ostergren, J., Patrono, C., Seferovic, P., Uva, M. S., Taskinen, M.-R., Tendera, M., Tuomilehto, J., Valensi, P., Zamorano, J. L.

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Locally applied mononuclear bone marrow cells restore angiogenesis and promote wound healing in a type 2 diabetic patient by Humpert, P M, Bärtsch, U, Konrade, I, Hammes, H-P, Morcos, M, Kasper, M, Bierhaus, A, Nawroth, P P

“…We treated a patient with type 2 diabetes suffering from chronic venous and neuro-ischemic wounds not healing under standard care with local application of…”
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Endothelial survival factors and spatial completion, but not pericyte coverage of retinal capillaries determine vessel plasticity by Hoffmann, J, Feng, Y, vom Hagen, F, Hillenbrand, A, Lin, J, Erber, R, Vajkoczy, P, Gourzoulidou, E, Waldmann, H, Giannis, A, Wolburg, H, Shani, M, Jaeger, V, Weich, H. A, Preissner, K. T, Hoffmann, S, Deutsch, U, Hammes, H.-P

“…ABSTRACTPericyte loss and capillary regression are characteristic for incipient diabetic retinopathy. Pericyte recruitment is involved in vessel maturation,…”
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