Search Results - "Hammers, Daniel E"
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Streptococcal peptides and their roles in host-microbe interactions
Published in Frontiers in cellular and infection microbiology (16-10-2023)“…The genus encompasses many bacterial species that are associated with hosts, ranging from asymptomatic colonizers and commensals to pathogens with a…”
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The Role of Host-Cellular Responses in COVID-19 Endothelial Dysfunction
Published in Current drug targets (01-01-2022)“…SARS-CoV2, Severe acute respiratory syndrome coronavirus 2, is a novel member of the human coronavirus family that has recently emerged worldwide to cause…”
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Streptolysin S targets the sodium-bicarbonate cotransporter NBCn1 to induce inflammation and cytotoxicity in human keratinocytes during Group A Streptococcal infection
Published in Frontiers in cellular and infection microbiology (01-11-2022)“…Group A (GAS, ) is a Gram-positive human pathogen that employs several secreted and surface-bound virulence factors to manipulate its environment, allowing it…”
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Synthetic Peptide Libraries Designed From a Minimal Alpha-Helical Domain of AS-48-Bacteriocin Homologs Exhibit Potent Antibacterial Activity
Published in Frontiers in microbiology (12-11-2020)“…The circularized bacteriocin enterocin AS-48 produced by sp. exhibits antibacterial activity through membrane disruption. The membrane-penetrating activity of…”
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Group A Streptococcus- Induced Activation of Human Plasminogen Is Required for Keratinocyte Wound Retraction and Rapid Clot Dissolution
Published in Frontiers in cardiovascular medicine (10-06-2021)“…Invasive outcomes of Group A (GAS) infections that involve damage to skin and other tissues are initiated when these bacteria colonize and disseminate an open…”
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Novel antimicrobial peptide discovery using machine learning and biophysical selection of minimal bacteriocin domains
Published in Drug development research (01-02-2020)“…Bacteriocins, the ribosomally produced antimicrobial peptides of bacteria, represent an untapped source of promising antibiotic alternatives. However,…”
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Finding a Match: The Role of Ion Transporters in Streptolysin S-Mediated Group A Streptococcal Infection
Published 01-01-2023“…Group A Streptococcus (GAS, Streptococcus pyogenes) is a Gram-positive, human-associated bacterium that ranges from an asymptomatic colonizer to a significant…”
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