Search Results - "Hammerman, Marc R."

Classic and current opinion in embryonic organ transplantation by Hammerman, Marc R.

“…Here, we review the rationale for the use of organs from embryonic donors, antecedent investigations and recent work from our own laboratory, exploring the…”
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Development of a novel xenotransplantation strategy for treatment of diabetes mellitus in rat hosts and translation to non-human primates by Hammerman, Marc R.

“…Transplantation therapy for diabetes is limited by unavailability of donor organs and outcomes complicated by immunosuppressive drug toxicity…”
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Organogenetic tolerance by Hammerman, Marc R.

“…Transplantation therapy for humans is limited by insufficient availability of donor organs and outcomes are complicated by the toxicity of immunosuppressive…”
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Xenotransplantation of pancreatic and kidney primordia—Where do we stand? by Hammerman, Marc R

“…Abstract Lack of donor availability limits the number of human donor organs. The need for host immunosuppression complicates transplantation procedures. It is…”
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Xenotransplantation of Embryonic Pig Kidney or Pancreas to Replace the Function of Mature Organs by Hammerman, Marc R.

“…Lack of donor availability limits the number of human donor organs. The need for host immunosuppression complicates transplantation procedures…”
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Engraftment of Insulin-Producing Cells from Porcine Islets in Non-Immune-Suppressed Rats or Nonhuman Primates Transplanted Previously with Embryonic Pig Pancreas by Hammerman, Marc R.

“…Transplantation therapy for diabetes is limited by unavailability of donor organs and outcomes complicated by immunosuppressive drug toxicity…”
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Prolongation of Life in Anephric Rats following de novo Renal Organogenesis by Rogers, Sharon A., Hammerman, Marc R.

“…One solution to the shortage of human organs available for transplantation envisions growing new organs in situ. This can be accomplished by transplantation of…”
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Organogenesis of Kidney and Endocrine Pancreas: The Window Opens by Hammerman, Marc R.

“…Growing new organs in situ by implanting developing animal organ primordia (organogenesis) represents a novel solution to the problem of limited supply for…”
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Transplantation of metanephroi across the major histocompatibility complex in rats by Rogers, S A, Liapis, H, Hammerman, M R

“…To determine whether transplanted metanephroi grow, differentiate, and function in hosts that differ in major histocompatibility complex loci (RT1 loci in…”
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Growing new endocrine pancreas in situ by Hammerman, Marc R

“…Type 1 diabetes mellitus is a major cause of endstage renal disease in young adults. Maintenance of normoglycemia in type 1 diabetics using exogenous insulin…”
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Engraftment of cells from porcine islets of Langerhans following transplantation of pig pancreatic primordia in non-immunosuppressed diabetic rhesus macaques by Rogers, Sharon A., Tripathi, Piyush, Mohanakumar, Thalachallour, Liapis, Helen, Cheng, Feng, Talcott, Michael R., Faulkner, Chad, Hammerman, Marc R.

“…Transplantation therapy for human diabetes is limited by the toxicity of immunosuppressive drugs. If toxicity can be minimized, there will still be a shortage…”
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Growing new kidneys in situ by Hammerman, Marc R

“…One novel solution to the shortage of human organs available for transplantation envisions "growing" new organs in situ via xenotransplantation of developing…”
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Generation and use of renal cells for replacement therapies by Hammerman, Marc R.

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Assessing intrarenal nonperfusion and vascular leakage in acute kidney injury with multinuclear (1) H/(19) F MRI and perfluorocarbon nanoparticles by Hu, Lingzhi, Chen, Junjie, Yang, Xiaoxia, Senpan, Angana, Allen, John S, Yanaba, Noriko, Caruthers, Shelton D, Lanza, Gregory M, Hammerman, Marc R, Wickline, Samuel A

“…We sought to develop a unique sensor-reporter approach for functional kidney imaging that employs circulating perfluorocarbon nanoparticles and multinuclear…”
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Assessing intrarenal nonperfusion and vascular leakage in acute kidney injury with multinuclear 1H/19F MRI and perfluorocarbon nanoparticles by Hu, Lingzhi, Chen, Junjie, Yang, Xiaoxia, Senpan, Angana, Allen, John S., Yanaba, Noriko, Caruthers, Shelton D., Lanza, Gregory M., Hammerman, Marc R., Wickline, Samuel A.

“…Purpose We sought to develop a unique sensor‐reporter approach for functional kidney imaging that employs circulating perfluorocarbon nanoparticles and…”
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Fibroblast growth factor 2 promotes microvessel formation from mouse embryonic aorta by Akimoto, Tetsu, Hammerman, Marc R

“…To delineate the roles that oxygen and fibroblast growth factors (FGFs) play in the process of angiogenesis from the embryonic aorta, we cultured mouse…”
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Underpinnings of cellular organ replacement therapies by Hammerman, Marc R.

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Normalization of glucose post-transplantation into diabetic rats of pig pancreatic primordia preserved in vitro by Rogers, Sharon A., Hammerman, Marc R.

“…Embryonic day (E) 28 (E28) pig pancreatic primordia transplanted into the mesentery of non-immunosuppresed steptozotocin (STZ)-diabetic Lewis rats normalize…”
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Microvessel formation from mouse embryonic aortic explants is oxygen and VEGF dependent by Akimoto, Tetsu, Liapis, Helen, Hammerman, Marc R

“…To delineate the roles of O(2) and vascular endothelial growth factor (VEGF) in the process of angiogenesis from the embryonic aorta, we cultured mouse…”
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Microvessel formation from mouse aorta is stimulated in vitro by secreted VEGF and extracts from metanephroi by Akimoto, Tetsu, Hammerman, Marc R

“…We have demonstrated that during culture under 5% O(2,) the addition of recombinant human VEGF or FGF2 to mouse embryonic aorta explants (thoracic level to…”
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