Search Results - "Hammerl, Peter"
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CagA Phosphorylation in Helicobacter pylori-Infected B Cells Is Mediated by the Nonreceptor Tyrosine Kinases of the Src and Abl Families
Published in Infection and immunity (01-09-2016)“…CagA is one of the most important virulence factors of the human pathogen Helicobacter pylori CagA expression can be associated with the induction of severe…”
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Hospitalisation patterns in interstitial lung diseases: data from the EXCITING-ILD registry
Published in Respiratory research (04-01-2024)“…Interstitial lung diseases (ILD) comprise a heterogeneous group of mainly chronic lung diseases with more than 200 entities and relevant differences in disease…”
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Disease trajectories in interstitial lung diseases - data from the EXCITING-ILD registry
Published in Respiratory research (06-03-2024)“…Interstitial lung diseases (ILD) comprise a heterogeneous group of mainly chronic lung diseases with different disease trajectories. Progression (PF-ILD)…”
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4
Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity
Published in Molecular oncology (01-09-2020)“…Activation of hedgehog/glioma‐associated oncogene homolog (HH/GLI) signaling induces basal cell carcinoma (BCC) and establishes an immunosuppressive tumor…”
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Neoantigen Expression in Steady-State Langerhans Cells Induces CTL Tolerance
Published in The Journal of immunology (1950) (01-09-2017)“…The skin hosts a variety of dendritic cells (DCs), which act as professional APC to control cutaneous immunity. Langerhans cells (LCs) are the only DC subset…”
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Molecular and biochemical analysis of the first ARA6 homologue, a RAB5 GTPase, from green algae
Published in Journal of experimental botany (01-12-2013)“…RAB5 GTPases are important regulators of endosomal membrane traffic in yeast, plants, and animals. A specific subgroup of this family, the ARA6 group, has been…”
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Immune Reactions against Gene Gun Vaccines Are Differentially Modulated by Distinct Dendritic Cell Subsets in the Skin
Published in PloS one (01-06-2015)“…The skin accommodates multiple dendritic cell (DC) subsets with remarkable functional diversity. Immune reactions are initiated and modulated by the triggering…”
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8
Comparing Proteolytic Fingerprints of Antigen-Presenting Cells during Allergen Processing
Published in International journal of molecular sciences (08-06-2017)“…Endolysosomal processing has a critical influence on immunogenicity as well as immune polarization of protein antigens. In industrialized countries, allergies…”
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Structural integrity of the antigen is a determinant for the induction of T-helper type-1 immunity in mice by gene gun vaccines against E. coli beta-galactosidase
Published in PloS one (2014)“…The type of immune response is critical for successful protection and typically determined by pathogen-associated danger molecules. In contrast, protein…”
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Epidermal Langerhans Cells Are Dispensable for Humoral and Cell-Mediated Immunity Elicited by Gene Gun Immunization
Published in Journal of Immunology (15-07-2007)“…Gene gun immunization, i.e., bombardment of skin with DNA-coated particles, is an efficient method for the administration of DNA vaccines. Direct transfection…”
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11
Phenotypic characterization of alveolar monocyte recruitment in acute respiratory distress syndrome
Published in American journal of physiology. Lung cellular and molecular physiology (01-07-2000)“…In 49 acute respiratory distress syndrome (ARDS) patients, the phenotype of alveolar macrophages (AMs) was analyzed by flow cytometry. Bronchoalveolar lavage…”
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12
Allergy multivaccines created by DNA shuffling of tree pollen allergens
Published in Journal of allergy and clinical immunology (01-08-2007)“…Background The major allergens of trees belonging to the Fagales order are collectively known as the Bet v 1 family. Members of the Fagales order have distinct…”
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13
Characterization of the cell death modes and the associated changes in cellular energy supply in response to AlPcS4-PDT
Published in Photochemical & photobiological sciences (01-03-2002)“…Photodynamic therapy (PDT) can result in both types of cell death, apoptosis or necrosis. Several steps in the induction and execution of apoptosis depend on…”
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14
Quantification of histamine in blood plasma and cell culture supernatants: a validated one-step gas chromatography–mass spectrometry method
Published in Analytical biochemistry (15-09-2002)“…A novel one-step ethylchloroformate (ECF) derivatization of histamine in biological liquid matrices that allows the sensitive quantification by gas…”
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Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo-controlled, phase 2b trial
Published in The lancet respiratory medicine (01-05-2021)“…Pirfenidone has been shown to slow disease progression in patients with idiopathic pulmonary fibrosis (IPF). However, there are few treatment options for…”
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TNF revisited: TNF-independent antitumor activity in sera of mice sensitized with Propionibacterium acnes and challenged with lipopolysaccharide
Published in Journal of leukocyte biology (01-12-2003)“…Sera of mice sensitized with bacteria and subsequently challenged with lipopolysaccharide promote hemorrhagic necrosis of tumors in vivo and display cytotoxic…”
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IL‐31 transgenic mice show reduced allergen‐induced lung inflammation
Published in European journal of immunology (01-01-2021)“…Interleukin‐31 (IL‐31) is a Th2 cell–derived cytokine that has been closely linked to pruritic skin inflammation. More recently, enhanced IL‐31 serum levels…”
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Endobronchial Coil System versus Standard-of-Care Medical Management in the Treatment of Subjects with Severe Emphysema
Published in Respiration (01-08-2021)“…Bronchoscopic lung volume reduction using endobronchial coils is a new treatment for patients with severe emphysema. To date, the benefits have been modest and…”
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Inhibition of Suppressive T Cell Factor 1 (TCF-1) Isoforms in Naive CD4+ T Cells Is Mediated by IL-4/STAT6 Signaling
Published in The Journal of biological chemistry (14-01-2011)“…The Wnt pathway transcription factor T cell factor 1 (TCF-1) plays essential roles in the control of several developmental processes, including T cell…”
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Langerin+ dermal dendritic cells are critical for CD8+ T cell activation and IgH γ-1 class switching in response to gene gun vaccines
Published in The Journal of immunology (1950) (01-02-2011)“…The C-type lectin langerin/CD207 was originally discovered as a specific marker for epidermal Langerhans cells (LC). Recently, additional and distinct subsets…”
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