Search Results - "Hammer, Sarah K"
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Biosensor for branched-chain amino acid metabolism in yeast and applications in isobutanol and isopentanol production
Published in Nature communications (12-01-2022)“…Branched-chain amino acid (BCAA) metabolism fulfills numerous physiological roles and can be harnessed to produce valuable chemicals. However, the lack of…”
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Mitochondrial Compartmentalization Confers Specificity to the 2‑Ketoacid Recursive Pathway: Increasing Isopentanol Production in Saccharomyces cerevisiae
Published in ACS synthetic biology (20-03-2020)“…Recursive elongation pathways produce compounds of increasing carbon-chain length with each iterative cycle. Of particular interest are 2-ketoacids derived…”
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Harnessing yeast organelles for metabolic engineering
Published in Nature chemical biology (01-08-2017)“…The organelles and subcellular compartments of yeast provide distinct environments and physical separation from the cytosol, enabling opportunities to target…”
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Uncovering the role of branched-chain amino acid transaminases in Saccharomyces cerevisiae isobutanol biosynthesis
Published in Metabolic engineering (01-11-2017)“…Isobutanol and other branched-chain higher alcohols (BCHAs) are promising advanced biofuels derived from the degradation of branched-chain amino acids (BCAAs)…”
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Xylose utilization stimulates mitochondrial production of isobutanol and 2-methyl-1-butanol in Saccharomyces cerevisiae
Published in Biotechnology for biofuels (20-09-2019)“…Branched-chain higher alcohols (BCHAs), including isobutanol and 2-methyl-1-butanol, are promising advanced biofuels, superior to ethanol due to their higher…”
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Biological lignocellulose solubilization: comparative evaluation of biocatalysts and enhancement via cotreatment
Published in Biotechnology for biofuels (12-01-2016)“…Feedstock recalcitrance is the most important barrier impeding cost-effective production of cellulosic biofuels. Pioneer commercial cellulosic ethanol…”
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The role of AdhE on ethanol tolerance and production in Clostridium thermocellum
Published in The Journal of biological chemistry (01-08-2024)“…Many anaerobic microorganisms use the bifunctional aldehyde and alcohol dehydrogenase enzyme, AdhE, to produce ethanol. One such organism is Clostridium…”
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Metabolic engineering: Biosensors get the green light
Published in Nature chemical biology (01-11-2016)“…A novel approach recruits the largest prokaryotic family of ligand-induced transcriptional regulators to develop a new class of biosensors in yeast based on…”
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Biosensors get the green light
Published in Nature chemical biology (18-10-2016)“…A novel approach recruits the largest prokaryotic family of ligand-induced transcriptional regulators to develop a new class of biosensors in yeast based on…”
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Metabolic Engineering of Saccharomyces cerevisiae for Enhanced Production of Branched-Chain Higher Alcohols
Published 01-01-2020“…Branched-chain higher alcohols (BCHAs) are promising advanced biofuels with properties that enable their use as complete gasoline substitutes in spark-ignition…”
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Dissertation -
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Xylose utilization stimulates mitochondrial production of isobutanol and 2-methyl-1-butanol in Saccharomyces cerevisiae
Published in Biotechnology for biofuels (20-09-2019)“…Abstract Background Branched-chain higher alcohols (BCHAs), including isobutanol and 2-methyl-1-butanol, are promising advanced biofuels, superior to ethanol…”
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Journal Article