Search Results - "Hammer, J A"

Optimization of cerebellar purkinje neuron cultures and development of a plasmid-based method for purkinje neuron-specific, miRNA-mediated protein knockdown by Alexander, C J, Hammer, 3rd, J A

“…We present a simple and efficient method to knock down proteins specifically in Purkinje neurons (PN) present in mixed mouse primary cerebellar cultures. This…”
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TGF-β1 alters esophageal epithelial barrier function by attenuation of claudin-7 in eosinophilic esophagitis by Nguyen, N, Fernando, S D, Biette, K A, Hammer, J A, Capocelli, K E, Kitzenberg, D A, Glover, L E, Colgan, S P, Furuta, G T, Masterson, J C

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Effect of ADP and Ionic Strength on the Kinetic and Motile Properties of Recombinant Mouse Myosin V by Wang, Fei, Chen, Lingfeng, Arcucci, Oreste, Harvey, Estelle V., Bowers, Blair, Xu, Yuhui, Hammer, John A., Sellers, James R.

“…Mouse myosin V is a two-headed unconventional myosin with an extended neck that binds six calmodulins. Double-headed (heavy meromyosin-like) and single-headed…”
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Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions by Jung, G. (National Institutes of Health, Bethesda, MD.), Wu, X, Hammer, J.A. III

“…Dictyostelium cells that lack the myoB isoform were previously shown to exhibit reduced efficiencies of phagocytosis and chemotactic aggregation ("streaming")…”
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Defective Granule Exocytosis in Rab27a-Deficient Lymphocytes from Ashen Mice by Haddad, Elias K., Wu, Xufeng, Hammer, John A., Henkart, Pierre A.

“…Because mutations in Rab27a have been linked to immune defects in humans, we have examined cytotoxic lymphocyte function in ashen mice, which contain a…”
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Two-headed binding of a processive myosin to F-actin by Knight, Peter J, Walker, Matthew L, Burgess, Stan A, Sellers, James R, Wang, Fei, Hammer, John A, Trinick, John

“…Myosins are motor proteins in cells. They move along actin by changing shape after making stereospecific interactions with the actin subunits. As these are…”
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Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle by Wu, X, Rao, K, Bowers, M B, Copeland, N G, Jenkins, N A, Hammer, 3rd, J A

“…The peripheral accumulation of melanosomes characteristic of wild-type mouse melanocytes is driven by a cooperative process involving long-range,…”
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The Dictyostelium CARMIL protein links capping protein and the Arp2/3 complex to type I myosins through their SH3 domains by Jung, G, Remmert, K, Wu, X, Volosky, J M, Hammer, 3rd, J A

“…Fusion proteins containing the Src homology (SH)3 domains of Dictyostelium myosin IB (myoB) and IC (myoC) bind a 116-kD protein (p116), plus nine other…”
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Myosin V associates with melanosomes in mouse melanocytes: evidence that myosin V is an organelle motor by Wu, X, Bowers, B, Wei, Q, Kocher, B, Hammer, 3rd, J A

“…Mice with mutations at the dilute locus exhibit a 'washed out' or 'diluted' coat color. The pigments that are responsible for the coloration of mammalian hair…”
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Functions of unconventional myosins by Wu, Xufeng, Jung, Goeh, Hammer, John A

“…To date, fourteen classes of unconventional myosins have been identified. Recent reports have implicated a number of these myosins in organelle transport, and…”
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Sequence, expression pattern, intracellular localization, and targeted disruption of the Dictyostelium myosin ID heavy chain isoform by Jung, G, Fukui, Y, Martin, B, Hammer, J.A. III

“…The complete sequence of the Dictyostelium myosin ID (DMID) heavy chain isoform has been determined from cDNA and genomic clones. Like the DMIB isoform…”
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Generation and Characterization of Dictyostelium Cells Deficient in a Myosin I Heavy Chain Isoform by Jung, Goeh, Hammer, John A.

“…Motile activities such as chemotaxis and phagocytosis, which occur in Dictyostelium cells lacking myosin II, may be dependent upon myosin I. To begin to…”
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The Heavy Chain of Acanthamoeba Myosin IB is a Fusion of Myosin-Like and Non-Myosin-Like Sequences by Jung, Goeh, Korn, Edward D., Hammer, John A.

“…Acanthamoeba castellanii myosins IA and IB demonstrate the catalytic properties of a myosin and can support analogues of contractile and motile activity in…”
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Myosin Va bound to phagosomes binds to F-actin and delays microtubule-dependent motility by Al-Haddad, A, Shonn, M A, Redlich, B, Blocker, A, Burkhardt, J K, Yu, H, Hammer, 3rd, J A, Weiss, D G, Steffen, W, Griffiths, G, Kuznetsov, S A

“…We established a light microscopy-based assay that reconstitutes the binding of phagosomes purified from mouse macrophages to preassembled F-actin in vitro…”
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The structure and function of unconventional myosins: a review by Hammer, 3rd, J A

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A radiometric assay for aspartoacylase activity in cultured oligodendrocytes by Madhavarao, C.N, Hammer, J.A, Quarles, R.H, Namboodiri, M.A.A

“…Recent studies have shown that aspartoacylase (ASPA), the defective enzyme in Canavan disease, is detectable in the brain only in the oligodendrocytes…”
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Dictyostelium discoideum Contains a Gene Encoding a Myosin I Heavy Chain by Jung, Goeh, Saxe, Charles L., Kimmel, Alan R., Hammer, John A.

“…We have cloned and completely sequenced a gene encoding the heavy chain of Dictyostelium myosin I. Like the myosin I molecules from Acanthamoeba, the…”
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Glutamate receptor targeting in the postsynaptic spine involves mechanisms that are independent of myosin Va by Petralia, Ronald S., Wang, Ya-Xian, Sans, Nathalie, Worley, Paul F., Hammer Iii, John A., Wenthold, Robert J.

“…Targeting of glutamate receptors (GluRs) to synapses involves rapid movement of intracellular receptors. This occurs in forms of synaptic upregulation of…”
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Complete Nucleotide Sequence and Deduced Polypeptide Sequence of a Nonmuscle Myosin Heavy Chain Gene from Acanthamoeba: Evidence of a Hinge in the Rodlike Tail by Hammer, John A., Bowers, Blair, Paterson, Bruce M., Korn, Edward D.

“…We have completely sequenced a gene encoding the heavy chain of myosin II, a nonmuscle myosin from the soil ameba Acanthamoeba castellanii. The gene spans 6…”
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Structural Invariance of Constitutively Active and Inactive Mutants of Acanthamoeba Myosin IC Bound to F-Actin in the Rigor and ADP-Bound States by Carragher, Bridget O., Cheng, Naiqian, Wang, Zhen-Yuan, Korn, Edward D., Reilein, Amy, Belnap, David M., Hammer, John A., Steven, Alasdair C.

“…The three single-headed monomeric myosin I isozymes of Acanthamoeba castellanii (AMIs)--AMIA, AMIB, and AMIC--are among the best-studied of all myosins. We…”
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