Search Results - "Hammarström, Clara"
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Nuclear IL-33 restrains the early conversion of fibroblasts to an extracellular matrix-secreting phenotype
Published in Scientific reports (08-01-2021)“…Interleukin (IL)-33 is a cytokine that appears to mediate fibrosis by signaling via its receptor ST2 (IL-33R/IL1RL1). It is also, however, a protein that after…”
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Immune Cell Composition in Human Non-small Cell Lung Cancer
Published in Frontiers in immunology (01-02-2019)“…Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death in the world. Immunological analysis of the tumor microenvironment…”
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3
Adoptive Transfer of Tumor-Specific Th2 Cells Eradicates Tumors by Triggering an In Situ Inflammatory Immune Response
Published in Cancer research (Chicago, Ill.) (01-12-2016)“…Adoptive cell therapy (ACT) trials to date have focused on transfer of autologous tumor-specific cytotoxic CD8 T cells; however, the potential of CD4 T helper…”
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4
Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer
Published in Nature communications (15-03-2011)“…The immune system can both promote and suppress cancer. Chronic inflammation and proinflammatory cytokines such as interleukin (IL)-1 and IL-6 are considered…”
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5
Exploring the potential effect of paricalcitol on markers of inflammation in de novo renal transplant recipients
Published in PloS one (16-12-2020)“…Following a successful renal transplantation circulating markers of inflammation may remain elevated, and systemic inflammation is associated with worse…”
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Kidney-transplanted Adolescents—Nonadherence and Graft Outcomes During the Transition Phase: A Nationwide Analysis, 2000–2020
Published in Transplantation (08-12-2022)“…Background. The transition from pediatric to young adult care is a vulnerable period for the renal transplant patient. We aimed to identify medication…”
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7
Inflammatory Bowel Disease-Associated Interleukin-33 Is Preferentially Expressed in Ulceration-Associated Myofibroblasts
Published in The American journal of pathology (01-12-2010)“…Interleukin-33 (IL-33) is a novel member of the interleukin-1 family that induces mucosal pathology in vivo and may drive fibrosis development and…”
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8
Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
Published in Communications biology (24-04-2020)“…The development of immune checkpoint inhibitors represents a major breakthrough in cancer therapy. Nevertheless, a substantial number of patients fail to…”
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Very Low Frequency of Pathological Findings in One-year Protocol Biopsies of Uneventful Standard Risk Kidney Transplant Recipients: Results From the Nordic Protocol Biopsy Study
Published in Transplantation direct (01-05-2024)“…The clinical significance of kidney transplant protocol biopsies has been debated. We studied the frequency of borderline changes and T cell-mediated rejection…”
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10
Early introduction of oral paricalcitol in renal transplant recipients. An open-label randomized study
Published in Transplant international (01-08-2017)“…In stable renal transplant recipients with hyperparathyroidism, previous studies have indicated that vitamin D agonist treatment might have anti-proteinuric…”
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11
The Tankyrase Inhibitor OM-153 Demonstrates Antitumor Efficacy and a Therapeutic Window in Mouse Models
Published in Cancer research communications (01-04-2022)“…The catalytic enzymes tankyrase 1 and 2 (TNKS1/2) alter protein turnover by poly-ADP-ribosylating target proteins, which earmark them for degradation by the…”
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12
Rituximab efficiently depletes B cells in lung tumors and normal lung tissue
Published in F1000 research (2016)“…Rituximab is a monoclonal antibody that targets the CD20 B-cell-specific antigen and is widely used as therapy for B-cell lymphoma. Since rituximab depletes…”
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13
The Immune Landscape of Human Primary Lung Tumors Is Th2 Skewed
Published in Frontiers in immunology (18-11-2021)“…Tumor-specific T helper (Th) cells have a central role in the immune response against cancer. However, there exist distinct Th cell subsets with very different…”
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14
Kidney-transplanted Adolescents—Nonadherence and Graft Outcomes During the Transition Phase: A Nationwide Analysis, 2000–2020
Published in Transplantation (01-05-2023)“…The transition from pediatric to young adult care is a vulnerable period for the renal transplant patient. We aimed to identify medication nonadherence…”
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15
A man in his 40s with diabetes, enlarged lacrimal gland and kidney failure
Published in Tidsskrift for den Norske Lægeforening (22-11-2016)Get full text
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16
Lack of interleukin-33 and its receptor does not prevent calcipotriol-induced atopic dermatitis-like inflammation in mice
Published in Scientific reports (15-04-2020)“…Current studies addressing the influence of interleukin-33 or its receptor (IL-33R/ST2) on development of atopic dermatitis-like inflammation in mice have…”
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17
A novel somatic mutation in GNB2 provides new insights to the pathogenesis of Sturge–Weber syndrome
Published in Human molecular genetics (13-10-2021)“…Abstract Sturge–Weber syndrome (SWS) is a neurocutaneous disorder characterized by vascular malformations affecting skin, eyes and leptomeninges of the brain,…”
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Kidney biopsy diagnosis in childhood in the Norwegian Kidney Biopsy Registry and the long-term risk of kidney replacement therapy: a 25-year follow-up
Published in Pediatric nephrology (Berlin, West) (01-04-2023)“…Background There is scarce information on biopsy-verified kidney disease in childhood and its progression to chronic kidney disease stage 5 (CKD 5). This study…”
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19
Antibody combinations for optimized staining of macrophages in human lung tumours
Published in Scandinavian journal of immunology (01-07-2020)“…The analysis of tumour‐associated macrophages (TAMs) has a high potential to predict cancer recurrence and response to immunotherapy. However, the…”
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Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor
Published in Virology journal (10-01-2020)“…BK Polyomavirus (BKPyV) causes premature graft failure in 1 to 15% of kidney transplant (KT) recipients. High-level BKPyV-viruria and BKPyV-DNAemia precede…”
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