Search Results - "Hamman, Josias H."

Composition and applications of Aloe vera leaf gel by Hamman, Josias H

“…Many of the health benefits associated with Aloe vera have been attributed to the polysaccharides contained in the gel of the leaves. These biological…”
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Chitosan based polyelectrolyte complexes as potential carrier materials in drug delivery systems by Hamman, Josias H

“…Chitosan has been the subject of interest for its use as a polymeric drug carrier material in dosage form design due to its appealing properties such as…”
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Review of natural compounds for potential skin cancer treatment by Chinembiri, Tawona N, du Plessis, Lissinda H, Gerber, Minja, Hamman, Josias H, du Plessis, Jeanetta

“…Most anti-cancer drugs are derived from natural resources such as marine, microbial and botanical sources. Cutaneous malignant melanoma is the most aggressive…”
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Polymeric plant-derived excipients in drug delivery by Beneke, Carien E, Viljoen, Alvaro M, Hamman, Josias H

“…Drug dosage forms contain many components in addition to the active pharmaceutical ingredient(s) to assist in the manufacturing process as well as to optimise…”
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Transdermal Drug Delivery Enhancement by Compounds of Natural Origin by Fox, Lizelle T., Gerber, Minja, Plessis, Jeanetta Du, Hamman, Josias H.

“…The transdermal route of administration offers an alternative pathway for systemic drug delivery with numerous advantages over conventional routes…”
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Paracellular drug absorption enhancement through tight junction modulation by Lemmer, Hendrik J R, Hamman, Josias H

“…Inclusion of absorption-enhancing agents in dosage forms is one approach to improve the bioavailability of active pharmaceutical ingredients with low membrane…”
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Drug Bioavailability Enhancing Agents of Natural Origin (Bioenhancers) that Modulate Drug Membrane Permeation and Pre-Systemic Metabolism by Peterson, Bianca, Weyers, Morné, Steenekamp, Jan H, Steyn, Johan D, Gouws, Chrisna, Hamman, Josias H

“…Many new chemical entities are discovered with high therapeutic potential, however, many of these compounds exhibit unfavorable pharmacokinetic properties due…”
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Fixed-Dose Combination Formulations in Solid Oral Drug Therapy: Advantages, Limitations, and Design Features by Wilkins, Christi A, Hamman, Hannlie, Hamman, Josias H, Steenekamp, Jan H

“…Whilst monotherapy is traditionally the preferred treatment starting point for chronic conditions such as hypertension and diabetes, other diseases require the…”
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Formulation of Chitosan Microparticles for Enhanced Intranasal Macromolecular Compound Delivery: Factors That Influence Particle Size during Ionic Gelation by Weyers, Morné, Peterson, Bianca, Hamman, Josias H, Steenekamp, Jan H

“…Therapeutic macromolecules (e.g., protein and peptide drugs) present bioavailability challenges via extravascular administration. The nasal route presents an…”
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Beneficial Pharmacokinetic Drug Interactions: A Tool to Improve the Bioavailability of Poorly Permeable Drugs by Gerber, Werner, Steyn, Johan D, Kotzé, Awie F, Hamman, Josias H

“…Simultaneous oral intake of herbs, supplements, foods and drugs with other drug(s) may result in pharmacokinetic or pharmacodynamic interactions with the…”
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Combination therapy of Western drugs and herbal medicines: recent advances in understanding interactions involving metabolism and efflux by Gouws, Chrisna, Steyn, Dewald, Du Plessis, Lissinda, Steenekamp, Jan, Hamman, Josias H

“…While complementary and alternative medicine markets prosper with an increasing number of consumers of herbal medicines, there is an associated likelihood for…”
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What are the dangers of drug interactions with herbal medicines? by Gouws, Chrisna, Hamman, Josias H

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Permeation of PLGA nanoparticles across different in vitro models by Nkabinde, Lindiwe A, Shoba-Zikhali, Lungile N N, Semete-Makokotlela, Boitumelo, Kalombo, Lonji, Swai, Hulda S, Hayeshi, Rose, Naicker, Brendon, Hillie, Thembela K, Hamman, Josias H

“…Many drug delivery systems have indicated improvement in delivery of various drug molecules and among these biodegradable and biocompatible polymers such as…”
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In vitro wound healing and cytotoxic activity of the gel and whole-leaf materials from selected aloe species by Fox, Lizelle T., Mazumder, Anisha, Dwivedi, Anupma, Gerber, Minja, du Plessis, Jeanetta, Hamman, Josias H.

“…Aloe vera is one of the most important medicinal plants in the world with applications in the cosmetic industry and also in the tonic or health drink product…”
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Natural products in anti-obesity therapy by Vermaak, Ilze, Viljoen, Alvaro M, Hamman, Josias H

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Direct compression of chitosan: process and formulation factors to improve powder flow and tablet performance by Buys, Gerhard M, du Plessis, Lissinda H, Marais, Andries F, Kotze, Awie F, Hamman, Josias H

“…Chitosan is a polymer derived from chitin that is widely available at relatively low cost, but due to compression challenges it has limited application for the…”
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Formulation of Medicated Chewing Gum Containing Sceletium tortuosum and Process Optimization Utilizing the SeDeM Diagram Expert System by Viljoen, Joe M., van der Walt, Sonja, Hamman, Josias H.

“…Sceletium tortuosum is one of the most promising medicinal plant species for treating anxiety and depression. Traditionally, aerial parts are chewed…”
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Recent developments in our understanding of the implications of traditional African medicine on drug metabolism by Gouws, Chrisna, Hamman, Josias H

“…The use of traditional herbal medicines has become increasingly popular globally, but in some countries, it is the main or sometimes even the only healthcare…”
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Comparison of RPMI 2650 cell layers and excised sheep nasal epithelial tissues in terms of nasal drug delivery and immunocytochemistry properties by Gerber, Werner, Svitina, Hanna, Steyn, Dewald, Peterson, Bianca, Kotzé, Awie, Weldon, Ché, Hamman, Josias H.

“…Nasal drug administration has been identified as a potential alternative to oral drug administration, especially for systemic delivery of large molecular…”
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A sub-chronic Xysmalobium undulatum hepatotoxicity investigation in HepG2/C3A spheroid cultures compared to an in vivo model by Calitz, Carlemi, Hamman, Josias H., Fey, Stephen J., Viljoen, Alvaro M., Gouws, Chrisna, Wrzesinski, Krzysztof

“…Traditional herbal medicines are utilized by 27 million South Africans. Xysmalobium undulatum (Uzara) is one of the most widely used traditional medicinal…”
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