Search Results - "Hammad, Maha M."

SARS-CoV-2: Possible recombination and emergence of potentially more virulent strains by Haddad, Dania, John, Sumi Elsa, Mohammad, Anwar, Hammad, Maha M, Hebbar, Prashantha, Channanath, Arshad, Nizam, Rasheeba, Al-Qabandi, Sarah, Al Madhoun, Ashraf, Alshukry, Abdullah, Ali, Hamad, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd

“…COVID-19 is challenging healthcare preparedness, world economies, and livelihoods. The infection and death rates associated with this pandemic are strikingly…”
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Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes by Qaddoumi, Mohammad G., Alanbaei, Muath, Hammad, Maha M., Al Khairi, Irina, Cherian, Preethi, Channanath, Arshad, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd, Abu-Farha, Mohamed, Abubaker, Jehad

“…Myeloperoxidase (MPO) is positively associated with obesity and diet-induced insulin resistance. Angiopoietin-like protein 6 (ANGPTL6) regulates metabolic…”
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Increased LRG1 Levels in Overweight and Obese Adolescents and Its Association with Obesity Markers, Including Leptin, Chemerin, and High Sensitivity C-Reactive Protein by Alhammad, Rashed, Abu-Farha, Mohamed, Hammad, Maha M, Thanaraj, Thangavel Alphonse, Channanath, Arshad, Alam-Eldin, Nada, Al-Sabah, Reem, Shaban, Lemia, Alduraywish, Abdulrahman, Al-Mulla, Fahd, Rahman, Abdur, Abubaker, Jehad

“…Leucine-rich α-2 glycoprotein1 (LRG1) is a member of the leucine-rich repeat (LRR) family that is implicated in multiple diseases, including cancer, aging, and…”
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Prognostic Genetic Markers for Thrombosis in COVID-19 Patients: A Focused Analysis on D-Dimer, Homocysteine and Thromboembolism by Abu-Farha, Mohamed, Al-Sabah, Salman, Hammad, Maha M, Hebbar, Prashantha, Channanath, Arshad Mohamed, John, Sumi Elsa, Taher, Ibrahim, Almaeen, Abdulrahman, Ghazy, Amany, Mohammad, Anwar, Abubaker, Jehad, Arefanian, Hossein, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse

“…COVID-19 is caused by Severe Acute Respiratory Syndrome Coronavirus-2, which has infected over thirty eight million individuals worldwide. Emerging evidence…”
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LRG1 Associates with Iron Deficiency Anemia Markers in Adolescents by Alhammad, Rashed, Abu-Farha, Mohamed, Rahman, Abdur, Thanaraj, Thangavel Alphonse, Shaban, Lemia, Alsabah, Reem, Hamad, Samar, Hammad, Maha M, Channanath, Arshad, Al-Mulla, Fahd, Abubaker, Jehad

“…Leucine-rich α-2 glycoprotein1 (LRG1) has been shown to be associated with several health conditions; however, its association with iron deficiency anemia,…”
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MAGI proteins can differentially regulate the signaling pathways of 5-HT 2A R by enhancing receptor trafficking and PLC recruitment by Hammad, Maha M, Dunn, Henry A, Ferguson, Stephen S G

“…MAGI proteins are Membrane-Associated Guanylate Kinase Inverted proteins that belong to the MAGUK family. They are scaffolding proteins that were shown to…”
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Single nucleotide polymorphisms in vitamin D binding protein and 25-hydroxylase genes affect vitamin D levels in adolescents of Arab ethnicity in Kuwait by Rahman, Abdur, Abu-Farha, Mohamed, Channanath, Arshad, Hammad, Maha M., Anoop, Emil, Chandy, Betty, Melhem, Motasem, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse, Abubaker, Jehad

“…Vitamin D deficiency (VDD) is widespread in the Arab world despite ample sunshine throughout the year. In our previous study, lifestyle and socio-demographic…”
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The miR-668 binding site variant rs1046322 on WFS1 is associated with obesity in Southeast Asians by Hammad, Maha M., Abu-Farha, Mohamed, Hebbar, Prashantha, Anoop, Emil, Chandy, Betty, Melhem, Motasem, Channanath, Arshad, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse, Abubaker, Jehad

“…The Wolfram syndrome 1 gene ( WFS1) is the main causative locus for Wolfram syndrome, an inherited condition characterized by childhood-onset diabetes…”
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Neurotransmitters in Type 2 Diabetes and the Control of Systemic and Central Energy Balance by Al-Sayyar, Amnah, Hammad, Maha M, Williams, Michayla R, Al-Onaizi, Mohammed, Abubaker, Jehad, Alzaid, Fawaz

“…Efficient signal transduction is important in maintaining the function of the nervous system across tissues. An intact neurotransmission process can regulate…”
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Adolescent obesity and ANGPTL8: correlations with high sensitivity C-reactive protein, leptin, and chemerin by Hammad, Maha M, Channanath, Arshad M, Abu-Farha, Mohamed, Rahman, Abdur, Al Khairi, Irina, Cherian, Preethi, Alramah, Tahani, Alam-Eldin, Nada, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse, Abubaker, Jehad

“…Angiopoietin-like proteins (ANGPTLs) mediate many metabolic functions. We had recently reported increased plasma levels of ANGPTL8 in obese adults of Arab…”
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Profiling of Insulin-Like Growth Factor Binding Proteins (IGFBPs) in Obesity and Their Association With Ox-LDL and Hs-CRP in Adolescents by Rahman, Abdur, Hammad, Maha M, Al Khairi, Irina, Cherian, Preethi, Al-Sabah, Reem, Al-Mulla, Fahd, Abu-Farha, Mohamed, Abubaker, Jehad

“…Insulin-like growth factor binding proteins (IGFBPs) are critical modulators of metabolism. In adults, IGFBPs are associated with obesity and insulin…”
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Potential Role of N-Cadherin in Diagnosis and Prognosis of Diabetic Nephropathy by Ali, Hamad, Abu-Farha, Mohamed, Hammad, Maha M., Devarajan, Sriraman, Bahbahani, Yousif, Al-Khairi, Irina, Cherian, Preethi, Alsairafi, Zahra, Vijayan, Vidya, Al-Mulla, Fahd, Attar, Abdulnabi Al, Abubaker, Jehad

“…Diabetic nephropathy (DN) is a serious complication of diabetes affecting about half the people with diabetes and the leading cause of end stage renal disease…”
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MC4R Variant rs17782313 Associates With Increased Levels of DNAJC27, Ghrelin, and Visfatin and Correlates With Obesity and Hypertension in a Kuwaiti Cohort by Hammad, Maha M., Abu-Farha, Mohamed, Hebbar, Prashantha, Cherian, Preethi, Al Khairi, Irina, Melhem, Motasem, Alkayal, Fadi, Alsmadi, Osama, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd, Abubaker, Jehad

“…Melanocortin 4 receptor (MC4R), a notable component of the melanocortin system, regulates appetite, body weight, and energy homeostasis. Genome-wide…”
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Structural analysis of setmelanotide binding to MC4R variants in comparison to wild-type receptor by Hammad, Maha M., Mohammad, Anwar, Alam-Eldin, Nada, Madhu, Dhanya, Al-Mulla, Fahd, Abu-Farha, Mohamed, Abubaker, Jehad

“…Melanocortin 4 receptor (MC4R) has a well-established role in regulating appetite, food intake and energy homeostasis. Setmelanotide is an MC4R agonist…”
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Discovery of natural products to block SARS-CoV-2 S-protein interaction with Neuropilin-1 receptor: A molecular dynamics simulation approach by Alshawaf, Eman, Hammad, Maha M., Marafie, Sulaiman K., Ali, Hamad, Al-Mulla, Fahd, Abubaker, Jehad, Mohammad, Anwar

“…Neuropilin-1 (NRP1) is a widely expressed cell surface receptor protein characterized by its pleiotropic function. Recent reports highlighted NRP1 as an…”
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Correlation of circulating ANGPTL5 levels with obesity, high sensitivity C-reactive protein and oxidized low-density lipoprotein in adolescents by Hammad, Maha M., Abu-Farha, Mohamed, Al-Taiar, Abdullah, Alam-Eldin, Nada, Al-Sabah, Reem, Shaban, Lemia, Al-Mulla, Fahd, Abubaker, Jehad, Rahman, Abdur

“…Angiopoietin-like proteins (ANGPTL) is a family of eight members known to play an important role in metabolic diseases. Of these, ANGPTL5 is suggested to…”
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MAGI proteins can differentially regulate the signaling pathways of 5-HT2AR by enhancing receptor trafficking and PLC recruitment by Hammad, Maha M., Dunn, Henry A., Ferguson, Stephen S.G.

“…MAGI proteins are Membrane-Associated Guanylate Kinase Inverted proteins that belong to the MAGUK family. They are scaffolding proteins that were shown to…”
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Role of cystic fibrosis transmembrane conductance regulator-associated ligand (CAL) in regulating the trafficking and signaling of corticotropin-releasing factor receptor 1 by Hammad, Maha M., Dunn, Henry A., Walther, Cornelia, Ferguson, Stephen S.G.

“…Corticotropin releasing factor (CRF) receptor1 (CRFR1) is associated with psychiatric illness and is a proposed target for the treatment of anxiety and…”
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Na+/H+ Exchanger Regulatory Factor-1 Is Involved in Chemokine Receptor Homodimer CCR5 Internalization and Signal Transduction but Does Not Affect CXCR4 Homodimer or CXCR4-CCR5 Heterodimer by Hammad, Maha M., Kuang, Yi-Qun, Yan, Ronald, Allen, Heather, Dupré, Denis J.

“…Chemokine receptors are members of the G protein-coupled receptor (GPCR) family. CCR5 is also the principal co-receptor for macrophage-tropic strains of human…”
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Rab1 interacts directly with the β2-adrenergic receptor to regulate receptor anterograde trafficking by Hammad, Maha M, Kuang, Yi-Qun, Morse, Alexa, Dupré, Denis J

“…Very little is understood about the trafficking of G protein-coupled receptors (GPCRs) from the endoplasmic reticulum (ER) to the plasma membrane. Rab…”
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