Search Results - "Hammad, Maha M"

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    SARS-CoV-2: Possible recombination and emergence of potentially more virulent strains by Haddad, Dania, John, Sumi Elsa, Mohammad, Anwar, Hammad, Maha M, Hebbar, Prashantha, Channanath, Arshad, Nizam, Rasheeba, Al-Qabandi, Sarah, Al Madhoun, Ashraf, Alshukry, Abdullah, Ali, Hamad, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd

    Published in PloS one (25-05-2021)
    “…COVID-19 is challenging healthcare preparedness, world economies, and livelihoods. The infection and death rates associated with this pandemic are strikingly…”
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    Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes by Qaddoumi, Mohammad G., Alanbaei, Muath, Hammad, Maha M., Al Khairi, Irina, Cherian, Preethi, Channanath, Arshad, Thanaraj, Thangavel Alphonse, Al-Mulla, Fahd, Abu-Farha, Mohamed, Abubaker, Jehad

    Published in Scientific reports (10-04-2020)
    “…Myeloperoxidase (MPO) is positively associated with obesity and diet-induced insulin resistance. Angiopoietin-like protein 6 (ANGPTL6) regulates metabolic…”
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    LRG1 Associates with Iron Deficiency Anemia Markers in Adolescents by Alhammad, Rashed, Abu-Farha, Mohamed, Rahman, Abdur, Thanaraj, Thangavel Alphonse, Shaban, Lemia, Alsabah, Reem, Hamad, Samar, Hammad, Maha M, Channanath, Arshad, Al-Mulla, Fahd, Abubaker, Jehad

    Published in Nutrients (01-07-2023)
    “…Leucine-rich α-2 glycoprotein1 (LRG1) has been shown to be associated with several health conditions; however, its association with iron deficiency anemia,…”
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    MAGI proteins can differentially regulate the signaling pathways of 5-HT 2A R by enhancing receptor trafficking and PLC recruitment by Hammad, Maha M, Dunn, Henry A, Ferguson, Stephen S G

    Published in Cellular signalling (01-07-2018)
    “…MAGI proteins are Membrane-Associated Guanylate Kinase Inverted proteins that belong to the MAGUK family. They are scaffolding proteins that were shown to…”
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    The miR-668 binding site variant rs1046322 on WFS1 is associated with obesity in Southeast Asians by Hammad, Maha M., Abu-Farha, Mohamed, Hebbar, Prashantha, Anoop, Emil, Chandy, Betty, Melhem, Motasem, Channanath, Arshad, Al-Mulla, Fahd, Thanaraj, Thangavel Alphonse, Abubaker, Jehad

    Published in Frontiers in endocrinology (Lausanne) (04-10-2023)
    “…The Wolfram syndrome 1 gene ( WFS1) is the main causative locus for Wolfram syndrome, an inherited condition characterized by childhood-onset diabetes…”
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    Neurotransmitters in Type 2 Diabetes and the Control of Systemic and Central Energy Balance by Al-Sayyar, Amnah, Hammad, Maha M, Williams, Michayla R, Al-Onaizi, Mohammed, Abubaker, Jehad, Alzaid, Fawaz

    Published in Metabolites (01-03-2023)
    “…Efficient signal transduction is important in maintaining the function of the nervous system across tissues. An intact neurotransmission process can regulate…”
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    Profiling of Insulin-Like Growth Factor Binding Proteins (IGFBPs) in Obesity and Their Association With Ox-LDL and Hs-CRP in Adolescents by Rahman, Abdur, Hammad, Maha M, Al Khairi, Irina, Cherian, Preethi, Al-Sabah, Reem, Al-Mulla, Fahd, Abu-Farha, Mohamed, Abubaker, Jehad

    Published in Frontiers in endocrinology (Lausanne) (28-07-2021)
    “…Insulin-like growth factor binding proteins (IGFBPs) are critical modulators of metabolism. In adults, IGFBPs are associated with obesity and insulin…”
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    Potential Role of N-Cadherin in Diagnosis and Prognosis of Diabetic Nephropathy by Ali, Hamad, Abu-Farha, Mohamed, Hammad, Maha M., Devarajan, Sriraman, Bahbahani, Yousif, Al-Khairi, Irina, Cherian, Preethi, Alsairafi, Zahra, Vijayan, Vidya, Al-Mulla, Fahd, Attar, Abdulnabi Al, Abubaker, Jehad

    Published in Frontiers in endocrinology (Lausanne) (31-05-2022)
    “…Diabetic nephropathy (DN) is a serious complication of diabetes affecting about half the people with diabetes and the leading cause of end stage renal disease…”
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    Structural analysis of setmelanotide binding to MC4R variants in comparison to wild-type receptor by Hammad, Maha M., Mohammad, Anwar, Alam-Eldin, Nada, Madhu, Dhanya, Al-Mulla, Fahd, Abu-Farha, Mohamed, Abubaker, Jehad

    Published in Life sciences (1973) (15-10-2022)
    “…Melanocortin 4 receptor (MC4R) has a well-established role in regulating appetite, food intake and energy homeostasis. Setmelanotide is an MC4R agonist…”
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    Discovery of natural products to block SARS-CoV-2 S-protein interaction with Neuropilin-1 receptor: A molecular dynamics simulation approach by Alshawaf, Eman, Hammad, Maha M., Marafie, Sulaiman K., Ali, Hamad, Al-Mulla, Fahd, Abubaker, Jehad, Mohammad, Anwar

    Published in Microbial pathogenesis (01-09-2022)
    “…Neuropilin-1 (NRP1) is a widely expressed cell surface receptor protein characterized by its pleiotropic function. Recent reports highlighted NRP1 as an…”
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    Correlation of circulating ANGPTL5 levels with obesity, high sensitivity C-reactive protein and oxidized low-density lipoprotein in adolescents by Hammad, Maha M., Abu-Farha, Mohamed, Al-Taiar, Abdullah, Alam-Eldin, Nada, Al-Sabah, Reem, Shaban, Lemia, Al-Mulla, Fahd, Abubaker, Jehad, Rahman, Abdur

    Published in Scientific reports (14-04-2020)
    “…Angiopoietin-like proteins (ANGPTL) is a family of eight members known to play an important role in metabolic diseases. Of these, ANGPTL5 is suggested to…”
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    MAGI proteins can differentially regulate the signaling pathways of 5-HT2AR by enhancing receptor trafficking and PLC recruitment by Hammad, Maha M., Dunn, Henry A., Ferguson, Stephen S.G.

    Published in Cellular signalling (01-07-2018)
    “…MAGI proteins are Membrane-Associated Guanylate Kinase Inverted proteins that belong to the MAGUK family. They are scaffolding proteins that were shown to…”
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    Journal Article
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    Role of cystic fibrosis transmembrane conductance regulator-associated ligand (CAL) in regulating the trafficking and signaling of corticotropin-releasing factor receptor 1 by Hammad, Maha M., Dunn, Henry A., Walther, Cornelia, Ferguson, Stephen S.G.

    Published in Cellular signalling (01-10-2015)
    “…Corticotropin releasing factor (CRF) receptor1 (CRFR1) is associated with psychiatric illness and is a proposed target for the treatment of anxiety and…”
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    Na+/H+ Exchanger Regulatory Factor-1 Is Involved in Chemokine Receptor Homodimer CCR5 Internalization and Signal Transduction but Does Not Affect CXCR4 Homodimer or CXCR4-CCR5 Heterodimer by Hammad, Maha M., Kuang, Yi-Qun, Yan, Ronald, Allen, Heather, Dupré, Denis J.

    Published in The Journal of biological chemistry (05-11-2010)
    “…Chemokine receptors are members of the G protein-coupled receptor (GPCR) family. CCR5 is also the principal co-receptor for macrophage-tropic strains of human…”
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    Rab1 interacts directly with the β2-adrenergic receptor to regulate receptor anterograde trafficking by Hammad, Maha M, Kuang, Yi-Qun, Morse, Alexa, Dupré, Denis J

    Published in Biological chemistry (01-06-2012)
    “…Very little is understood about the trafficking of G protein-coupled receptors (GPCRs) from the endoplasmic reticulum (ER) to the plasma membrane. Rab…”
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