Search Results - "Hamlin, D M"

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  1. 1

    Comparative polyclonal antithymocyte globulin and antilymphocyte/antilymphoblast globulin anti-CD antigen analysis by flow cytometry by Bourdage, J S, Hamlin, D M

    Published in Transplantation (27-04-1995)
    “…Polyclonal antithymocyte globulin (ATG)/antilymphocyte and antilymphoblast globulins (ALG) antibodies have been used successfully in transplantation, aplastic…”
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    Sensitivity and specificity of isolated perfused guinea pig heart to test for drug-induced lengthening of QTc by Hamlin, R.L, Cruze, C.A, Mittelstadt, S.W, Kijtawornrat, A, Keene, B.W, Roche, B.M, Nakayama, T, Nakayama, H, Hamlin, D.M, Arnold, T

    “…Introduction: The purpose of this study was to determine the sensitivity and specificity for predicting the liability of a compound to lengthen QTc using…”
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  3. 3

    Assessment of drug-induced QT interval prolongation in conscious rabbits by Kijtawornrat, A., Ozkanlar, Y., Keene, B.W., Roche, B.M., Hamlin, D.M., Hamlin, R.L.

    “…Most preclinical trials are designed to identify potential torsadogenicity test only for surrogates of torsade de pointes, most commonly prolongation of the…”
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    Cisplatin nephrotoxicity in male beagle dogs: next-generation protein kidney safety biomarker tissue expression and related changes in urine by McDuffie, J E, Chen, Y, Ma, J Y, Lee, S, Lynch, K M, Hamlin, D M, Nguyen, L, Rizzolio, M, Sonee, M, Snook, S

    Published in Toxicology research (Cambridge) (01-01-2016)
    “…This 10-day (D) study was conducted to evaluate changes in traditional and newer kidney safety biomarker expression levels in dogs. Animals received cisplatin…”
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    Acute effects of escalating doses of amiodarone in isolated guinea pig hearts by BICER, S., PATCHELL, J. S., HAMLIN, D. M., HAMLIN, R. L.

    “…Bicer, S., Patchell, J. S., Hamlin, D. M., Hamlin, R. L. Acute effects of escalating doses of amiodarone in isolated guinea pig hearts. J. vet Pharmacol…”
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    Unrecognised and unregistered visual impairment by Robinson, R, Deutsch, J, Jones, H S, Youngson-Reilly, S, Hamlin, D M, Dhurjon, L, Fielder, A R

    Published in British journal of ophthalmology (01-10-1994)
    “…Recent community based studies have shown that only a minority of visually impaired people who are eligible to be registered as partially sighted or blind are…”
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    Use of the polymerase chain reaction to directly detect malaria parasites in blood samples from the Venezuelan Amazon by Laserson, K F, Petralanda, I, Hamlin, D M, Almera, R, Fuentes, M, Carrasquel, A, Barker, Jr, R H

    “…We have examined the reproducibility, sensitivity, and specificity of detecting Plasmodium falciparum using the polymerase chain reaction (PCR) and the…”
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    QT and RR Intervals in Conscious and Anesthetized Guinea Pigs with Highly Varying RR Intervals and Given QTc-Lengthening Test Articles by Hamlin, Robert L., Kijtawornrat, Anusak, Keene, Bruce W., Hamlin, David M.

    Published in Toxicological sciences (01-12-2003)
    “…A facile system for obtaining electrocardiograms from conscious animals was used to conduct studies on 12 animals studied both conscious and anesthetized, on 4…”
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    Effects of ambasilide in isolated perfused guinea pig heart: use dependence by Kijtawornrat, Anusak, Hamlin, Robert L, Hamlin, David M

    Published in Cardiovascular toxicology (01-01-2005)
    “…There has been increased interest in class III antiarrhythmic drugs for con-version of atrial fibrillation to sinus rhythm. Ambasilide, a class III…”
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    Effects of thalidomide on QTc, inotropy, and lusitropy in the isolated guinea pig heart by Hamlin, Robert L, Kijtawornrat, Anusak, Keene, Bruce W, Nakayama, Tomohiro, Nakayama, Hitomi, Hamlin, David M, Arnold, Tammy A

    Published in Cardiovascular toxicology (2004)
    “…There has been a resurgence in the use of thalidomide over the past several years; however, little is known about its potential cardiac toxicity. Isolated,…”
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  13. 13

    Identification and characterization of an anti-isoaspartic acid monoclonal antibody by Lehrman, S R, Hamlin, D M, Lund, M E, Walker, G A

    Published in Journal of protein chemistry (01-12-1992)
    “…The deamidation and rearrangement of protein-bound asparagine residues occurs when peptides and proteins are exposed to acidic or alkaline aqueous media. Asn99…”
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  14. 14

    Cisplatin nephrotoxicity in male beagle dogs: next-generation protein kidney safety biomarker tissue expression and related changes in urineElectronic supplementary information (ESI) available. See DOI: 10.1039/c5tx00497g by McDuffie, J. E, Chen, Y, Ma, J. Y, Lee, S, Lynch, K. M, Hamlin, D. M, Nguyen, L, Rizzolio, M, Sonee, M, Snook, S

    Published 27-06-2016
    “…This 10-day (D) study was conducted to evaluate changes in traditional and newer kidney safety biomarker expression levels in dogs. Animals received cisplatin…”
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    Predictors of Adverse Local Tissue Reaction in a High-Risk Population by Snyder, Matthew J., Weber, Margaret A., Kromka, Joseph J., Sims, Margaret M., Smith, Clair N., Daji, Akshay V., Kumar, Deepak, Borrero, Camilo G., Cordle, Andrew C., DiGioia, Anthony M., Hamlin, Brian R., Plakseychuk, Anton Y., Urish, Kenneth L.

    Published in Arthroplasty today (01-02-2022)
    “…Adverse local tissue reaction (ALTR) is a recognized complication of total hip arthroplasty (THA) with metal-on-polyethylene (MoP) bearing surface implants…”
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    Topical Tranexamic Acid Reduces Blood Loss and Transfusion Rates in Total Hip and Total Knee Arthroplasty by Konig, Gerhardt, MD, Hamlin, Brian R., MD, Waters, Jonathan H., MD

    Published in The Journal of arthroplasty (01-10-2013)
    “…Abstract The objective of this study was to determine if tranexamic acid (TXA) applied topically reduced postoperative bleeding and transfusion rates after…”
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    Trunnion Failure of the Recalled Low Friction Ion Treatment Cobalt Chromium Alloy Femoral Head by Urish, Kenneth L., MD, PhD, Hamlin, Brian R., MD, Plakseychuk, Anton Y., MD, PhD, Levison, Timothy J., MS, Higgs, Genymphas B., MS, Kurtz, Steven M., PhD, DiGioia, Anthony M., MD

    Published in The Journal of arthroplasty (01-09-2017)
    “…Abstract Background Gross trunnion failure (GTF) is a rare complication in total hip arthroplasty (THA) reported across a range of manufacturers. Specific lots…”
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