Search Results - "Hamlett, E D"

Regional binding of tau and amyloid PET tracers in Down syndrome autopsy brain tissue by Lemoine, L, Ledreux, A, Mufson, E J, Perez, S E, Simic, G, Doran, E, Lott, I, Carroll, S, Bharani, K, Thomas, S, Gilmore, A, Hamlett, E D, Nordberg, A, Granholm, A C

“…Tau pathology is a major age-related event in Down syndrome with Alzheimer's disease (DS-AD). Although recently, several different Tau PET tracers have been…”
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Exosomal biomarkers in Down syndrome and Alzheimer's disease by Hamlett, Eric D., Ledreux, Aurélie, Potter, Huntington, Chial, Heidi J., Patterson, David, Espinosa, Joaquin M., Bettcher, Brianne M., Granholm, Ann-Charlotte

“…Every person with Down syndrome (DS) has the characteristic features of Alzheimer's disease (AD) neuropathology in their brain by the age of forty, and most go…”
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RvE1 treatment prevents memory loss and neuroinflammation in the Ts65Dn mouse model of Down syndrome by Hamlett, Eric D., Hjorth, Erik, Ledreux, Aurélie, Gilmore, Anah, Schultzberg, Marianne, Granholm, Ann Charlotte

“…Inflammation can be resolved by pro‐homeostatic lipids called specialized pro‐resolving mediators (SPMs) upon activation of their receptors. Dysfunctional…”
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Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome by Hamlett, Eric D, Goetzl, Edward J, Ledreux, Aurélie, Vasilevko, Vitaly, Boger, Heather A, LaRosa, Angela, Clark, David, Carroll, Steven L, Carmona-Iragui, María, Fortea, Juan, Mufson, Elliott J, Sabbagh, Marwan, Mohammed, Abdul H, Hartley, Dean, Doran, Eric, Lott, Ira T, Granholm, Ann-Charlotte

“…Abstract Introduction Individuals with Down syndrome (DS) exhibit Alzheimer's disease (AD) neuropathology and dementia early in life. Blood biomarkers of AD…”
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