Search Results - "Hamilton, Sara R."

A RHAMM Mimetic Peptide Blocks Hyaluronan Signaling and Reduces Inflammation and Fibrogenesis in Excisional Skin Wounds by Tolg, Cornelia, Hamilton, Sara R, Zalinska, Ewa, McCulloch, Lori, Amin, Ripal, Akentieva, Natalia, Winnik, Francoise, Savani, Rashmin, Bagli, Darius J, Luyt, Len G, Cowman, Mary K, McCarthy, Jim B, Turley, Eva A

“…Hyaluronan is activated by fragmentation and controls inflammation and fibroplasia during wound repair and diseases (eg, cancer). Hyaluronan-binding peptides…”
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The Hyaluronan Receptors CD44 and Rhamm (CD168) Form Complexes with ERK1,2 That Sustain High Basal Motility in Breast Cancer Cells by Hamilton, Sara R., Fard, Shireen F., Paiwand, Frouz F., Tolg, Cornelia, Veiseh, Mandana, Wang, Chao, McCarthy, James B., Bissell, Mina J., Koropatnick, James, Turley, Eva A.

“…CD44 is an integral hyaluronan receptor that can promote or inhibit motogenic signaling in tumor cells. Rhamm is a nonintegral cell surface hyaluronan receptor…”
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RHAMM Promotes Interphase Microtubule Instability and Mitotic Spindle Integrity through MEK1/ERK1/2 Activity by Tolg, Cornelia, Hamilton, Sara R., Morningstar, Lyndsey, Zhang, Jing, Zhang, S., Esguerra, Kenneth V., Telmer, Patrick G., Luyt, Len G., Harrison, Rene, McCarthy, James B., Turley, Eva A.

“…An oncogenic form of RHAMM (receptor for hyaluronan-mediated motility, mouse, amino acids 163–794 termed RHAMMΔ163) is a cell surface hyaluronan receptor and…”
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Rhamm⁻/⁻ fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair by Tolg, Cornelia, Hamilton, Sara R, Nakrieko, Kerry-Ann, Kooshesh, Fatemeh, Walton, Paul, McCarthy, James B, Bissell, Mina J, Turley, Eva A

“…Rhamm (receptor for hyaluronan-mediated motility) is an hyaluronan binding protein with limited expression in normal tissues and high expression in advanced…”
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Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells by Brenner, Dirk, Brüstle, Anne, Lin, Gloria H. Y., Lang, Philipp A., Duncan, Gordon S., Knobbe-Thomsen, Christiane B., Paul, Michael St, Reardon, Colin, Tusche, Michael W., Snow, Bryan, Hamilton, Sara R., Pfefferle, Aline, Gilani, Syed O., Ohashi, Pamela S., Lang, Karl S., Mak, Tak W.

“…The ability to mount a strong immune response against pathogens is crucial for mammalian survival. However, excessive and uncontrolled immune reactions can…”
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Nuclear factor-κB1 controls the functional maturation of dendritic cells and prevents the activation of autoreactive T cells by Dissanayake, Dilan, Hall, Håkan, Berg-Brown, Nancy, Elford, Alisha R, Hamilton, Sara R, Murakami, Kiichi, Deluca, Leslie Summers, Gommerman, Jennifer L, Ohashi, Pamela S

“…Although maturation of dendritic cells can drive autoimmune responses in mice, it remains unclear whether intrinsic factors hold dendritic cells in a resting…”
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Glycogen Synthase Kinase-3 Modulates Cbl-b and Constrains T Cell Activation by Tran, Charles W, Saibil, Samuel D, Le Bihan, Thierry, Hamilton, Sara R, Lang, Karl S, You, Han, Lin, Amy E, Garza, Kristine M, Elford, Alisha R, Tai, Kelly, Parsons, Michael E, Wigmore, Kip, Vainberg, Mitchell G, Penninger, Josef M, Woodgett, James R, Mak, Tak W, Ohashi, Pamela S

“…The decision between T cell activation and tolerance is governed by the spatial and temporal integration of diverse molecular signals and events occurring…”
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Nuclear factor-[kappa]B1 controls the functional maturation of dendritic cells and prevents the activation of autoreactive T cells by Dissanayake, Dilan, Hall, Håkan, Berg-brown, Nancy, Elford, Alisha R, Hamilton, Sara R, Murakami, Kiichi, Deluca, Leslie Summers, Gommerman, Jennifer L, Ohashi, Pamela S

“…Mature dendritic cells (DCs) are crucial for the induction of adaptive immune responses and perturbed DC homeostasis can result in autoimmune disease. Either…”
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Rhamm-/- fibroblasts are defective in CD44-mediated ERK 1,2 motogenic signaling, leading to defective skin wound repair by Tolg, Cornelia, Hamilton, Sara R, Kerry-Ann Nakrieko, Kooshesh, Fatemeh

“…Rhamm (receptor for hyaluronan-mediated motility) is an hyaluronan binding protein with limited expression in normal tissues and high expression in advanced…”
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The hyaluronan receptors CD44 and RHAMM (CD168) form complexeswith ERK1,2, which sustain high basal motility in breast cancercells by Hamilton, Sara R., Fard, Shireen F., Paiwand, Frouz F., Tolg,Cornelia, Veiseh, Mandana, Wang, Chao, McCarthy, James B., Bissell, MinaJ, Koropatnick, James, Turley, Eva A.

“…CD44 is an integral hyaluronan receptor that can promote or inhibit motogenic signaling in tumor cells. Rhamm is a non-integral cell surface hyaluronan…”
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THE HYALURONAN RECEPTORS CD44 AND RHAMM (CD168) FORM COMPLEXES WITH ERK1,2, WHICH SUSTAIN HIGH BASAL MOTILITY IN BREAST CANCER CELLS by Hamilton, Sara R., Fard, Shireen F., Paiwand, Frouz F., Tolg, Cornelia, Veiseh, Mandana, Wang, Chao, McCarthy, James B., Bissell, Mina J., Koropatnick, James, Turley, Eva A.

“…CD44 is an integral hyaluronan receptor that can promote or inhibit motogenic signaling in tumor cells. Rhamm is a non-integral cell surface hyaluronan…”
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Rhamm −/− fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair by Tolg, Cornelia, Hamilton, Sara R., Nakrieko, Kerry-Ann, Kooshesh, Fatemeh, Walton, Paul, McCarthy, James B., Bissell, Mina J., Turley, Eva A.

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Rhamm super(-/-) fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair by Tolg, Cornelia, Hamilton, Sara R, Nakrieko, Kerry-Ann, Kooshesh, Fatemeh, Walton, Paul, McCarthy, James B, Bissell, Mina J, Turley, Eva A

“…Rhamm (receptor for hyaluronan-mediated motility) is an hyaluronan binding protein with limited expression in normal tissues and high expression in advanced…”
Get full text