Search Results - "Hamilton, Michael J."
-
1
The immune thrombocytopenic purpura (ITP) bleeding score: assessment of bleeding in patients with ITP
Published in British journal of haematology (01-07-2007)“…Summary A method for objective quantification of bleeding symptoms in immune thrombocytopenic purpura (ITP) has not been established. The ITP Bleeding Scale…”
Get full text
Journal Article -
2
Phase I and Pharmacologic Study of 17-(Allylamino)-17-Demethoxygeldanamycin in Adult Patients With Solid Tumors
Published in Journal of clinical oncology (20-03-2005)“…To determine the clinical toxicities of 17-(allylamino)-17-demethoxygeldanamycin (17-AAG) given as a 1-hour infusion daily for 5 days every 3 weeks. Nineteen…”
Get full text
Journal Article -
3
The interplay of long non-coding RNAs and MYC in cancer
Published in AIMS biophysics (01-01-2015)“…Long non-coding RNAs (lncRNAs) are a class of RNA molecules that are changing how researchers view eukaryotic gene regulation. Once considered to be…”
Get full text
Journal Article -
4
Evaluation of allele frequencies of inherited disease genes in subgroups of American Quarter Horses
Published in Journal of the American Veterinary Medical Association (2009)“…To estimate allele frequencies of the hyperkalaemic periodic paralysis (HYPP), lethal white foal syndrome (LWFS), glycogen branching enzyme deficiency (GBED),…”
Get full text
Journal Article -
5
Phase I study of a vaccine using recombinant vaccinia virus expressing PSA (rV-PSA) in patients with metastatic androgen-independent prostate cancer
Published in The Prostate (01-10-2002)“…BACKGROUND A Phase I trial of recombinant vaccinia prostate specific antigen (rV‐PSA) in patients with advanced metastatic prostate cancer was conducted. This…”
Get full text
Journal Article -
6
HOTAIRM1 lncRNA is downregulated in clear cell renal cell carcinoma and inhibits the hypoxia pathway
Published in Cancer letters (01-03-2020)“…HOXA Transcript Antisense RNA, Myeloid-Specific 1 (HOTAIRM1) is a conserved long non-coding RNA (lncRNA) involved in myeloid and neural differentiation that is…”
Get full text
Journal Article -
7
Global isoform-specific transcript alterations and deregulated networks in clear cell renal cell carcinoma
Published in Oncotarget (04-05-2018)“…Extensive genome-wide analyses of deregulated gene expression have now been performed for many types of cancer. However, most studies have focused on…”
Get full text
Journal Article -
8
MYC acetylated lysine residues drive oncogenic cell transformation and regulate select genetic programs for cell adhesion-independent growth and survival
Published in Genes & development (01-10-2023)“…The MYC oncogenic transcription factor is acetylated by the p300 and GCN5 histone acetyltransferases. The significance of MYC acetylation and the functions of…”
Get full text
Journal Article -
9
A Phase I Dose-Ranging Study of the Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of AVN944, an IMPDH Inhibitor, in Healthy Male Volunteers
Published in Journal of clinical pharmacology (01-01-2009)“…A phase I study of AVN944, an inosine monophosphate dehydrogenase (IMPDH) inhibitor, was carried out to assess its safety, tolerability, pharmacokinetics, and…”
Get full text
Journal Article -
10
Aristaless-Like Homeobox protein 1 (ALX1) variant associated with craniofacial structure and frontonasal dysplasia in Burmese cats
Published in Developmental biology (15-01-2016)“…Frontonasal dysplasia (FND) can have severe presentations that are medically and socially debilitating. Several genes are implicated in FND conditions,…”
Get full text
Journal Article -
11
The ubiquitin system: an essential component to unlocking the secrets of malaria parasite biology
Published in Molecular bioSystems (01-01-2014)“…Exploration of the ubiquitin system in eukaryotes has shown that the chemical modification of proteins by ubiquitin, known as ubiquitylation, is an incredibly…”
Get more information
Journal Article -
12
Applications and efficiencies of the first cat 63K DNA array
Published in Scientific reports (04-05-2018)“…The development of high throughput SNP genotyping technologies has improved the genetic dissection of simple and complex traits in many species including cats…”
Get full text
Journal Article -
13
The immunological and clinical effects of mutated ras peptide vaccine in combination with IL-2, GM-CSF, or both in patients with solid tumors
Published in Journal of translational medicine (24-02-2014)“…Mutant Ras oncogenes produce proteins that are unique to cancer cells and represent attractive targets for vaccine therapy. We have shown previously that…”
Get full text
Journal Article -
14
Author Correction: Applications and efficiencies of the first cat 63 K DNA array
Published in Scientific reports (12-03-2019)“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
Get full text
Journal Article -
15
Author Correction: Applications and efficiencies of the first cat 63K DNA array
Published in Scientific reports (04-06-2018)“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
Get full text
Journal Article -
16
Adaptive autonomous underwater vehicles for littoral surveillance
Published in Intelligent service robotics (01-10-2011)“…Autonomous underwater vehicles (AUVs) have gained more interest in recent years for military as well as civilian applications. One potential application of…”
Get full text
Journal Article -
17
A Phase I Pharmacologic and Pharmacodynamic Study of Pyrazoloacridine Given as a Weekly 24-Hour Continuous Intravenous Infusion in Adult Cancer Patients
Published in Clinical cancer research (01-07-2002)“…Purpose: Pyrazoloacridine (PZA) is an investigational nucleic acid binding agent that inhibits the activity of topoisomerases I and II through a mechanism…”
Get full text
Journal Article -
18
A phase I vaccine trial with peptides reflecting ras oncogene mutations of solid tumors
Published in Journal of immunotherapy (1997) (01-03-1999)“…Mutations in the ras genes occur in 20% of all human cancers. These genes, in turn, produce mutated proteins that are unique to cancer cells, rendering them…”
Get more information
Journal Article -
19
Multiculturalism on Campus: Theory, Models, and Practices for Understanding Diversity and Creating Inclusion
Published in Stylus Publishing, LLC (01-02-2011)“…As the diversity of the students on campus increases, the importance for everyone in authority to understand students' distinct cultures and how they perceive…”
Get more information
Book -
20
A Pharmacokinetically Guided Phase II Study of Carboxyamido-triazole in Androgen-independent Prostate Cancer
Published in Clinical cancer research (01-09-1999)“…We conducted a Phase II clinical trial of the antiproliferative, antimetastatic, and antiangiogenic agent carboxyamido-triazole (CAI), using pharmacokinetic…”
Get full text
Journal Article