Search Results - "Hamilton, Lauren E."
-
1
Sperm Redox System Equilibrium: Implications for Fertilization and Male Fertility
Published in Advances in experimental medicine and biology (2022)“…Structural and regulatory requirements of mammalian spermatozoa in both development and function make them extremely unique cells. Looking at the complexity of…”
Get more information
Journal Article -
2
Sperm Cohort-Specific Zinc Signature Acquisition and Capacitation-Induced Zinc Flux Regulate Sperm-Oviduct and Sperm-Zona Pellucida Interactions
Published in International journal of molecular sciences (19-03-2020)“…Building on our recent discovery of the zinc signature phenomenon present in boar, bull, and human spermatozoa, we have further characterized the role of zinc…”
Get full text
Journal Article -
3
Core Histones Are Constituents of the Perinuclear Theca of Murid Spermatozoa: An Assessment of Their Synthesis and Assembly during Spermiogenesis and Function after Gametic Fusion
Published in International journal of molecular sciences (01-08-2021)“…The perinuclear theca (PT) of the eutherian sperm head is a cytoskeletal-like structure that houses proteins involved in important cellular processes during…”
Get full text
Journal Article -
4
Age-related changes in the control of perturbation-evoked and voluntary arm movements
Published in Clinical neurophysiology (01-10-2012)“…Highlights ► Ageing leads to changes in the ability to produce perturbation-evoked arm responses following an unexpected loss of balance. ► Altering the…”
Get full text
Journal Article -
5
A Non-Synonymous Point Mutation in a WD-40 Domain Repeat of EML5 Leads to Decreased Bovine Sperm Quality and Fertility
Published in Frontiers in cell and developmental biology (05-04-2022)“…This study is part of a concerted effort to identify and phenotype rare, deleterious mutations that adversely affect sperm quality, or convey high…”
Get full text
Journal Article -
6
The complete mitochondrial genome of the plumed worm Diopatra cuprea (Annelida: Onuphidae)
Published in Mitochondrial DNA. Part B. Resources (2022)“…In this study, we describe the complete mitochondrial genome of Diopatra cuprea (Bosc, 1802). The mitogenome was found to contain 14,990 base pairs (67.53% A +…”
Get full text
Journal Article -
7
Biomarker-based high-throughput sperm phenotyping: Andrology in the age of precision medicine and agriculture
Published in Animal reproduction science (01-12-2024)“…Reproductive efficiency is crucial for animal agriculture. This economically important aspect can be influenced by environmental burdens, nutritional…”
Get full text
Journal Article -
8
The perforatorium and postacrosomal sheath of rat spermatozoa share common developmental origins and protein constituents
Published in Biology of reproduction (01-06-2019)“…The perinuclear theca (PT) is a cytosolic protein capsule that surrounds the nucleus of eutherian spermatozoa. Compositionally, it is divided into two regions:…”
Get full text
Journal Article -
9
The developmental origin and compartmentalization of glutathione-s-transferase omega 2 isoforms in the perinuclear theca of eutherian spermatozoa
Published in Biology of reproduction (01-10-2017)“…The perinuclear theca (PT) is a condensed, nonionic detergent resistant cytosolic protein layer encapsulating the sperm head nucleus. It can be divided into…”
Get full text
Journal Article -
10
Biomarker-based human and animal sperm phenotyping: the good, the bad and the ugly
Published in Biology of reproduction (12-06-2024)“…Conventional, brightfield-microscopic semen analysis provides important baseline information about sperm quality of an individual; however, it falls short of…”
Get full text
Journal Article -
11
WBP2 shares a common location in mouse spermatozoa with WBP2NL/PAWP and like its descendent is a candidate mouse oocyte-activating factor
Published in Biology of reproduction (01-12-2018)“…The sperm-borne oocyte-activating factor (SOAF) resides in the sperm perinuclear theca (PT). A consensus has been reached that SOAF most likely resides in the…”
Get full text
Journal Article -
12
Impact of sex and gender on axSpA diagnosis and outcomes
Published in Best practice & research. Clinical rheumatology (01-09-2023)“…Axial spondyloarthritis (axSpA) was historically considered a disease of men, largely due to the recognition of a more severe, progressive phenotype,…”
Get full text
Journal Article -
13
Sperm-borne glutathione-S-transferase omega 2 accelerates the nuclear decondensation of spermatozoa during fertilization in mice
Published in Biology of reproduction (01-08-2019)“…The postacrosomal sheath (PAS) of the perinuclear theca (PT) is the first compartment of the sperm head to solubilize into the ooplasm upon sperm-oocyte…”
Get full text
Journal Article -
14
Cell-Responsive Shape Memory Polymers
Published in ACS biomaterials science & engineering (11-07-2022)“…Recent decades have seen substantial interest in the development and application of biocompatible shape memory polymers (SMPs), a class of “smart materials”…”
Get full text
Journal Article -
15
Regional abundances of binder of sperm (BSP) proteins are negatively associated with the quality of frozen-thawed bovine spermatozoa
Published in Reproduction (Cambridge, England) (01-01-2024)“…The localization and abundance of the sperm BSP proteins correlate with in vitro fertility in domestic bulls used in artificial insemination service. Binder of…”
Get full text
Journal Article -
16
GSTO2 Isoforms Participate in the Oxidative Regulation of the Plasmalemma in Eutherian Spermatozoa during Capacitation
Published in Antioxidants (29-11-2019)“…In addition to perinuclear theca anchored glutathione-s-transferase omega 2 (GSTO2), whose function is to participate in sperm nuclear decondensation during…”
Get full text
Journal Article