Search Results - "Hamilton, Laura K."

Aberrant Lipid Metabolism in the Forebrain Niche Suppresses Adult Neural Stem Cell Proliferation in an Animal Model of Alzheimer’s Disease by Hamilton, Laura K., Dufresne, Martin, Joppé, Sandra E., Petryszyn, Sarah, Aumont, Anne, Calon, Frédéric, Barnabé-Heider, Fanie, Furtos, Alexandra, Parent, Martin, Chaurand, Pierre, Fernandes, Karl J.L.

“…Lipid metabolism is fundamental for brain development and function, but its roles in normal and pathological neural stem cell (NSC) regulation remain largely…”
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Stearoyl-CoA Desaturase inhibition reverses immune, synaptic and cognitive impairments in an Alzheimer’s disease mouse model by Hamilton, Laura K., Moquin-Beaudry, Gaël, Mangahas, Chenicka L., Pratesi, Federico, Aubin, Myriam, Aumont, Anne, Joppé, Sandra E., Légiot, Alexandre, Vachon, Annick, Plourde, Mélanie, Mounier, Catherine, Tétreault, Martine, Fernandes, Karl J. L.

“…The defining features of Alzheimer’s disease (AD) include alterations in protein aggregation, immunity, lipid metabolism, synapses, and learning and memory. Of…”
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Comparative analysis of methods to reduce activation signature gene expression in PBMCs by Andriamboavonjy, Lovatiana, MacDonald, Adam, Hamilton, Laura K., Labrecque, Marjorie, Boivin, Marie-Noёlle, Karamchandani, Jason, Stratton, Jo Anne, Tetreault, Martine

“…Preserving the in vivo cell transcriptome is essential for accurate profiling, yet factors during cell isolation including time ex vivo and temperature induce…”
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Central inhibition of stearoyl-CoA desaturase has minimal effects on the peripheral metabolic symptoms of the 3xTg Alzheimer’s disease mouse model by Hamilton, Laura K., M’Bra, Paule E. H., Mailloux, Sophia, Galoppin, Manon, Aumont, Anne, Fernandes, Karl J. L.

“…Evidence from genetic and epidemiological studies point to lipid metabolism defects in both the brain and periphery being at the core of Alzheimer’s disease…”
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Author Correction: Stearoyl-CoA Desaturase inhibition reverses immune, synaptic and cognitive impairments in an Alzheimer’s disease mouse model by Hamilton, Laura K., Moquin-Beaudry, Gaël, Mangahas, Chenicka L., Pratesi, Federico, Aubin, Myriam, Aumont, Anne, Joppé, Sandra E., Légiot, Alexandre, Vachon, Annick, Plourde, Mélanie, Mounier, Catherine, Tétreault, Martine, Fernandes, Karl J. L.

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Central canal ependymal cells proliferate extensively in response to traumatic spinal cord injury but not demyelinating lesions by Lacroix, Steve, Hamilton, Laura K, Vaugeois, Alexandre, Beaudoin, Stéfanny, Breault-Dugas, Christian, Pineau, Isabelle, Lévesque, Sébastien A, Grégoire, Catherine-Alexandra, Fernandes, Karl J L

“…The adult mammalian spinal cord has limited regenerative capacity in settings such as spinal cord injury (SCI) and multiple sclerosis (MS). Recent studies have…”
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Mammalian target of rapamycin signaling is a key regulator of the transit-amplifying progenitor pool in the adult and aging forebrain by Paliouras, Grigorios N, Hamilton, Laura K, Aumont, Anne, Joppé, Sandra E, Barnabé-Heider, Fanie, Fernandes, Karl J L

“…Adult forebrain neurogenesis is dynamically regulated. Multiple families of niche-derived cues have been implicated in this regulation, but the precise roles…”
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Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer's disease by Hamilton, Laura K., Aumont, Anne, Julien, Carl, Vadnais, Alexandra, Calon, Frédéric, Fernandes, Karl J. L.

“…Alzheimer’s disease (AD) affects cognitive modalities that are known to be regulated by adult neurogenesis, such as hippocampal‐ and olfactory‐dependent…”
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Aging and neurogenesis in the adult forebrain: what we have learned and where we should go from here by Hamilton, Laura K., Joppé, Sandra E., M. Cochard, Loїc, Fernandes, Karl J. L.

“…In the brains of adult vertebrates, including humans, neurogenesis occurs in restricted niches where it maintains cellular turnover and cognitive plasticity…”
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Neural stem cells and adult brain fatty acid metabolism: Lessons from the 3xTg model of Alzheimer's disease by Hamilton, Laura K., Fernandes, Karl J. L.

“…Neural stem cell (NSC) activity and adult neurogenesis are physiologically relevant regulators of adult brain structure, function and repair. Given these…”
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The Socio‐Economic Boundaries Shaping Young People's Lunchtime Food Practices on a School Day by Wills, Wendy J., Danesi, Giada, Kapetanaki, Ariadne B., Hamilton, Laura K.

“…Not enough is known about the relationship between socio‐economic deprivation and places where young people purchase food at lunchtime on a school day. This…”
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IDENTIFICATION OF A NOVEL LIPID-RELATED DRUG TARGET TO REACTIVATE ADULT NEURAL STEM CELLS IN ALZHEIMER'S DISEASE by Hamilton, Laura K, Joppe, Sandra E, Dufresne, Martin, Chaurand, Pierre, Petryszyn, Sarah, Parent, Martin, Fernandes, Karl J.L, Aumont, Anne, Furtos, Alexandra, Calon, Frederic

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Genetic targeting of neurogenic precursors in the adult forebrain ventricular epithelium by Joppé, Sandra E, Cochard, Loïc M, Levros, Louis-Charles, Hamilton, Laura K, Ameslon, Pierre, Aumont, Anne, Barnabé-Heider, Fanie, Fernandes, Karl JL

“…The ventricular epithelium of the adult forebrain is a heterogeneous cell population that is a source of both quiescent and activated neural stem cells (qNSCs…”
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Bone morphogenetic protein dominantly suppresses epidermal growth factor-induced proliferative expansion of adult forebrain neural precursors by Joppé, Sandra E, Hamilton, Laura K, Cochard, Loic M, Levros, Louis-Charles, Aumont, Anne, Barnabé-Heider, Fanie, Fernandes, Karl J L

“…A single asymmetric division by an adult neural stem cell (NSC) ultimately generates dozens of differentiated progeny, a feat made possible by the…”
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Acceleration of aging-dependent changes in adult neural stem cell populations in the 3XTg mouse model of Alzheimer's disease by Hamilton, Laura K, Aumont, Anne, Julien, Carl, Vadnais, Alexandra, Calon, Frédéric, Fernandes, Karl J.L

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Let Me Tell You Who I Am: Establishing a Federal Remedy for Interference with Online Identity by Hamilton, Laura K

“…The Internet connects us all in ways the law has yet to fully understand. In recent years, Google has developed into a powerful search engine that effectively…”
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Tennessee v. FCC by Hamilton, Laura K

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The Role of Family Income and Other Factors in Understanding the Food and Eating Practices of Young People in the Uk : a Mixed Methods Approach by Hamilton, Laura K

“…In the UK there are well recognised socio-economic inequalities in diet and health. However, research about dietary inequalities rarely focuses on young…”
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Aging and neurogenesis in the adult forebrain: what we have learned and where we should go from here : SPECIAL ISSUE: THE NEUROBIOLOGY OF AGING AND ALZHEIMER'S DISEASE by HAMILTON, Laura K, JOPPE, Sandra E, COCHARD, Loïc M, FERNANDES, Karl J. L

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O1‐04‐03: Identification of a Novel Lipid‐Related Drug Target to Reactivate Adult Neural Stem Cells in Alzheimer's Disease by Hamilton, Laura K., Joppe, Sandra E., Dufresne, Martin, Chaurand, Pierre, Petryszyn, Sarah, Parent, Martin, Fernandes, Karl J.L., Aumont, Anne, Furtos, Alexandra, Calon, Frederic

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