Search Results - "Hamilton, Jasmine L"

In vivo efficacy, toxicity and biodistribution of ultra-long circulating desferrioxamine based polymeric iron chelator by Hamilton, Jasmine L, Imran ul-haq, Muhammad, Abbina, Srinivas, Kalathottukaren, Manu Thomas, Lai, Benjamin F.L, Hatef, Azadeh, Unniappan, Suraj, Kizhakkedathu, Jayachandran N

“…Abstract Desferrioxamine (DFO) is currently in clinical use to remove iron from transfusion-dependent patients with β-thalassemia major, sickle-cell anemia and…”
Get full text

Design of Long Circulating Nontoxic Dendritic Polymers for the Removal of Iron in Vivo by Imran ul-haq, Muhammad, Hamilton, Jasmine L, Lai, Benjamin F. L, Shenoi, Rajesh A, Horte, Sonja, Constantinescu, Iren, Leitch, Heather A, Kizhakkedathu, Jayachandran N

“…Patients requiring chronic red blood cell (RBC) transfusions for inherited or acquired anemias are at risk of developing transfusional iron overload, which may…”
Get full text

Branched Multifunctional Polyether Polyketals: Variation of Ketal Group Structure Enables Unprecedented Control over Polymer Degradation in Solution and within Cells by Shenoi, Rajesh A, Narayanannair, Jayaprakash K, Hamilton, Jasmine L, Lai, Benjamin F. L, Horte, Sonja, Kainthan, Rajesh K, Varghese, Jos P, Rajeev, Kallanthottathil G, Manoharan, Muthiah, Kizhakkedathu, Jayachandran N

“…Multifunctional biocompatible and biodegradable nanomaterials incorporating specific degradable linkages that respond to various stimuli and with defined…”
Get full text

Clinically approved iron chelators influence zebrafish mortality, hatching morphology and cardiac function by Hamilton, Jasmine L, Hatef, Azadeh, Imran ul-Haq, Muhammad, Nair, Neelima, Unniappan, Suraj, Kizhakkedathu, Jayachandran N

“…Iron chelation therapy using iron (III) specific chelators such as desferrioxamine (DFO, Desferal), deferasirox (Exjade or ICL-670), and deferiprone (Ferriprox…”
Get full text

Iron Binding and Iron Removal Efficiency of Desferrioxamine Based Polymeric Iron Chelators: Influence of Molecular Size and Chelator Density by Hamilton, Jasmine L., ul‐haq, Muhammad Imran, Creagh, A. Louise, Haynes, Charles A., Kizhakkedathu, Jayachandran N.

“…Desferrioxamine (DFO) is a clinically approved, high affinity iron chelator used for the treatment of iron overload. Due to its short half‐life and toxicity,…”
Get full text

Polymeric nanocarriers for the treatment of systemic iron overload by Hamilton, Jasmine L, Kizhakkedathu, Jayachandran N

“…Desferrioxamine (DFO), deferiprone (L1) and desferasirox (ICL-670) are clinically approved iron chelators used to treat secondary iron overload. Although iron…”
Get full text

Clinically Approved Iron Chelators Influence Zebrafish Mortality, Hatching Morphology and Cardiac Function: e109880 by Hamilton, Jasmine L, Hatef, Azadeh, ul-haq, Muhammad Imran, Nair, Neelima, Unniappan, Suraj, Kizhakkedathu, Jayachandran N

“…Iron chelation therapy using iron (III) specific chelators such as desferrioxamine (DFO, Desferal), deferasirox (Exjade or ICL-670), and deferiprone (Ferriprox…”
Get full text