Search Results - "Hamers, A."

Population synthesis of triple systems in the context of mergers of carbon-oxygen white dwarfs by Hamers, A. S., Pols, O. R., Claeys, J. S. W., Nelemans, G.

“…Hierarchical triple systems are common among field stars yet their long-term evolution is poorly understood theoretically. In such systems Kozai cycles can be…”
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Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry by Winkels, Holger, Ehinger, Erik, Vassallo, Melanie, Buscher, Konrad, Dinh, Huy, Kobiyama, Kouji, Hamers, Anouk A.J, Cochain, Clément, Vafadarnejad, Ehsan, Saliba, Antoine-Emmanuel, Zernecke, Alma, Pramod, Akula Bala, Ghosh, Amlan, Michel, Nathaly Anto, Hoppe, Natalie, Hilgendorf, Ingo, Zirlik, Andreas, Hedrick, Catherine C, Ley, Klaus, Wolf, Dennis

“…RATIONALE:Atherosclerosis is a chronic inflammatory disease that is driven by the interplay of pro- and anti-inflammatory leukocytes in the aorta. Yet, the…”
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Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6Clow Monocytes while Preserving Macrophage Gene Function by Thomas, Graham D., Hanna, Richard N., Vasudevan, Neelakatan T., Hamers, Anouk A., Romanoski, Casey E., McArdle, Sara, Ross, Kevin D., Blatchley, Amy, Yoakum, Deborah, Hamilton, Bruce A., Mikulski, Zbigniew, Jain, Mukesh K., Glass, Christopher K., Hedrick, Catherine C.

“…Mononuclear phagocytes are a heterogeneous family that occupy all tissues and assume numerous roles to support tissue function and systemic homeostasis. Our…”
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CyTOF ® for the Masses by Iyer, Akshay, Hamers, Anouk A J, Pillai, Asha B

“…Mass cytometry has revolutionized immunophenotyping, particularly in exploratory settings where simultaneous breadth and depth of characterization of immune…”
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Human Blood Monocyte Subsets: A New Gating Strategy Defined Using Cell Surface Markers Identified by Mass Cytometry by Thomas, Graham D, Hamers, Anouk A.J, Nakao, Catherine, Marcovecchio, Paola, Taylor, Angela M, McSkimming, Chantel, Nguyen, Anh Tram, McNamara, Coleen A, Hedrick, Catherine C

“…OBJECTIVE—Human monocyte subsets are defined as classical (CD14CD16), intermediate (CD14CD16), and nonclassical (CD14CD16). Alterations in monocyte subset…”
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Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis by Hamers, Anouk A.J, Vos, Mariska, Rassam, Fadi, Marinković, Goran, Kurakula, Kondababu, van Gorp, Patrick J, de Winther, Menno P.J, Gijbels, Marion J.J, de Waard, Vivian, de Vries, Carlie J.M

“…RATIONALE:Nuclear receptor Nur77, also known as NR4A1, TR3, or NGFI-B, is expressed in human atherosclerotic lesions in macrophages, endothelial cells, T cells…”
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Deficiency of Nuclear Receptor Nur77 Aggravates Mouse Experimental Colitis by Increased NFκB Activity in Macrophages by Hamers, Anouk A J, van Dam, Laura, Teixeira Duarte, José M, Vos, Mariska, Marinković, Goran, van Tiel, Claudia M, Meijer, Sybren L, van Stalborch, Anne-Marieke, Huveneers, Stephan, Te Velde, Anje A, de Jonge, Wouter J, de Vries, Carlie J M

“…Nuclear receptor Nur77, also referred to as NR4A1 or TR3, plays an important role in innate and adaptive immunity. Nur77 is crucial in regulating the T helper…”
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6-Mercaptopurine reduces macrophage activation and gut epithelium proliferation through inhibition of GTPase Rac1 by Marinković, Goran, Hamers, Anouk A J, de Vries, Carlie J M, de Waard, Vivian

“…Inflammatory bowel disease is characterized by chronic intestinal inflammation. Azathioprine and its metabolite 6-mercaptopurine (6-MP) are effective…”
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Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance by Hamers, Anouk A J, Argmann, Carmen, Moerland, Perry D, Koenis, Duco S, Marinković, Goran, Sokolović, Milka, de Vos, Alex F, de Vries, Carlie J M, van Tiel, Claudia M

“…The nuclear orphan receptor Nur77 (NR4A1, TR3, or NGFI-B) has been shown to modulate the inflammatory response of macrophages. To further elucidate the role of…”
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Impact of the B Cell Growth Factor APRIL on the Qualitative and Immunological Characteristics of Atherosclerotic Plaques by Bernelot Moens, Sophie J, van Leuven, Sander I, Zheng, Kang H, Havik, Stefan R, Versloot, Miranda V, van Duivenvoorde, Leonie M, Hahne, Michael, Stroes, Erik S G, Baeten, Dominique L, Hamers, Anouk A J

“…Studies on the role of B lymphocytes in atherosclerosis development, have yielded contradictory results. Whereas B lymphocyte-deficiency aggravates…”
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Gastrointestinal digestion of dietary advanced glycation endproducts increases their pro-inflammatory potential by van der Lugt, T, Vrolijk, M F, Bovee, T F H, van Leeuwen, S P J, Vonsovic, S, Hamers, A, Opperhuizen, A, Bast, A

“…Thermal treatment of food products leads to the formation of dietary advanced glycation endproducts (dAGEs). It was previously shown that dAGEs induce TNF-α…”
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External Validation of the Colon Life Nomogram for Predicting 12-Week Mortality in Dutch Metastatic Colorectal Cancer Patients Treated with Trifluridine/Tipiracil in Daily Practice by Hamers, Patricia A. H, Wensink, G. Emerens, van Smeden, Maarten, Vink, Geraldine R, Smabers, Lidwien P, Lunenberg, Renee A, Laclé, Miangela M, Koopman, Miriam, May, Anne M, Roodhart, Jeanine M. L

“…Background: Predicting prognosis in refractory metastatic colorectal cancer (mCRC) patients is needed to guide decision making. The Colon Life nomogram was…”
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Nonclassical Monocytes in Health and Disease by Narasimhan, Prakash Babu, Marcovecchio, Paola, Hamers, Anouk A.J, Hedrick, Catherine C

“…Monocytes are innate blood cells that maintain vascular homeostasis and are early responders to pathogens in acute infections. There are three…”
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Limited Role of Nuclear Receptor Nur77 in Escherichia coli-Induced Peritonitis by Hamers, Anouk A J, Uleman, Sven, van Tiel, Claudia M, Kruijswijk, Daniëlle, van Stalborch, Anne-Marieke, Huveneers, Stephan, de Vries, Carlie J M, van 't Veer, Cornelis

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Deleting an Nr4a1 Super-Enhancer Subdomain Ablates Ly6C low Monocytes while Preserving Macrophage Gene Function by Thomas, Graham D, Hanna, Richard N, Vasudevan, Neelakatan T, Hamers, Anouk A, Romanoski, Casey E, McArdle, Sara, Ross, Kevin D, Blatchley, Amy, Yoakum, Deborah, Hamilton, Bruce A, Mikulski, Zbigniew, Jain, Mukesh K, Glass, Christopher K, Hedrick, Catherine C

“…Mononuclear phagocytes are a heterogeneous family that occupy all tissues and assume numerous roles to support tissue function and systemic homeostasis. Our…”
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Flexible amorphous and microcrystalline silicon tandem solar modules in the temporary superstrate concept by van den Donker, M.N., Gordijn, A., Stiebig, H., Finger, F., Rech, B., Stannowski, B., Bartl, R., Hamers, E.A.G., Schlatmann, R., Jongerden, G.J.

“…Encapsulated and series-connected amorphous silicon (a-Si:H) and microcrystalline silicon (μc-Si:H) based thin film silicon solar modules were developed in the…”
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Gamma-Irradiated Bacille Calmette-Guérin Vaccination Does Not Modulate the Innate Immune Response during Experimental Human Endotoxemia in Adult Males by Pickkers, Peter, Leentjens, Jenneke, Blok, Bastiaan, Arts, Rob J. W., Kox, Matthijs, Hamers, Linda A. C., Netea, Mihai G.

“…Bacille Calmette-Guérin (BCG) vaccine exerts nonspecific immunostimulatory effects and may therefore represent a novel therapeutic option to treat…”
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Human Monocyte Heterogeneity as Revealed by High-Dimensional Mass Cytometry by Hamers, Anouk A.J, Dinh, Huy Q, Thomas, Graham D, Marcovecchio, Paola, Blatchley, Amy, Nakao, Catherine S, Kim, Cheryl, McSkimming, Chantel, Taylor, Angela M, Nguyen, Anh T, McNamara, Coleen A, Hedrick, Catherine C

“…OBJECTIVE—Three distinct human monocyte subsets have been identified based on the surface marker expression of CD14 and CD16. We hypothesized that monocytes…”
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Shear-Induced Platelet Activation and Platelet Microparticle Formation at Blood Flow Conditions as in Arteries With a Severe Stenosis by Holme, Pal A, Orvim, Una, Hamers, Maria J.A.G, Solum, Nils O, Brosstad, Frank R, Barstad, R. Marius, Sakariassen, Kjell S

“…In the present study, we investigated whether high arterial shear stresses at various exposure times or a sudden increase in shear stress introduced by a…”
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Informing metastatic colorectal cancer patients by quantifying multiple scenarios for survival time based on real‐life data by Hamers, Patricia A. H., Elferink, Marloes A. G., Stellato, Rebecca K., Punt, Cornelis J. A., May, Anne M., Koopman, Miriam, Vink, Geraldine R.

“…Reported median overall survival (mOS) in metastatic colorectal cancer (mCRC) patients participating in systemic therapy trials has increased to over 30…”
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