Search Results - "Hamed, Kamal"

Safety and pharmacokinetics of SPR206 in subjects with varying degrees of renal impairment by Bruss, Jon B, Bader, Justin, Hamed, Kamal A

“…SPR206 is a novel polymyxin derivative with potent activity against susceptible and multidrug-resistant strains of , , , , and species. SPR206 is eliminated…”
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Efficacy of SPR720 in murine models of non-tuberculous mycobacterial pulmonary infection by Cotroneo, Nicole, Stokes, Suzanne S, Pucci, Michael J, Rubio, Aileen, Hamed, Kamal A, Critchley, Ian A

“…Non-tuberculous mycobacterial pulmonary disease (NTM-PD) is increasing worldwide, with Mycobacterium avium complex (MAC) and Mycobacterium abscessus as the…”
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Ceftobiprole Compared With Vancomycin Plus Aztreonam in the Treatment of Acute Bacterial Skin and Skin Structure Infections: Results of a Phase 3, Randomized, Double-blind Trial (TARGET) by Overcash, J Scott, Kim, Charles, Keech, Richard, Gumenchuk, Illia, Ninov, Borislav, Gonzalez-Rojas, Yaneicy, Waters, Michael, Simeonov, Simeon, Engelhardt, Marc, Saulay, Mikael, Ionescu, Daniel, Smart, Jennifer I, Jones, Mark E, Hamed, Kamal A

“…The development of novel broad-spectrum antibiotics, with efficacy against both gram-positive and gram-negative bacteria, has the potential to enhance…”
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A Phase 3, Randomized, Investigator-blinded Trial Comparing Ceftobiprole With a Standard-of-care Cephalosporin, With or Without Vancomycin, for the Treatment of Pneumonia in Pediatric Patients by Bosheva, Miroslava, Gujabidze, Rusudan, Károly, Éva, Nemeth, Agnes, Saulay, Mikael, Smart, Jennifer I., Hamed, Kamal A.

“…The advanced-generation, broad-spectrum, intravenous (IV) cephalosporin, ceftobiprole, is an effective and well-tolerated treatment for adults with…”
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Post-hoc analysis of the safety and efficacy of isavuconazole in older patients with invasive fungal disease from the VITAL and SECURE studies by Hamed, Kamal, Engelhardt, Marc, Kovanda, Laura L., Huang, Jin Ju, Yan, Jean, Aram, Jalal A.

“…Isavuconazole is a triazole with broad-spectrum antifungal activity. In this post-hoc analysis of two prospective clinical trials (VITAL and SECURE), the…”
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Hydraulic Risk Assessment on Historic Masonry Bridges Using Hydraulic Open-Source Software and Geomatics Techniques: A Case Study of the “Hannibal Bridge”, Italy by Ahmed Kamal Hamed Dewedar, Palumbo, Donato, Pepe, Massimiliano

“…This paper investigates the impact of flood-induced hydrodynamic forces and high discharge on the masonry arch “Hannibal Bridge” (called “Ponte di Annibale” in…”
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Impact of antibiotic pharmacokinetics in urine on recurrent bacteriuria following treatment of complicated urinary tract infections by Melnick, David, Talley, Angela K., Gupta, Vipul K., Critchley, Ian A., Eckburg, Paul B., Hamed, Kamal A., Bhatt, Nivedita, Moore, Gary, Austin, Daren, Rubino, Christopher M., Bhavnani, Sujata M., Ambrose, Paul G.

“…ABSTRACT The clinical relevance of bacteriuria following antibiotic treatment of complicated urinary tract infections in clinical trials remains controversial…”
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Ceftobiprole Activity against Bacteria from Skin and Skin Structure Infections in the United States from 2016 through 2018 by Flamm, Robert K, Duncan, Leonard R, Hamed, Kamal A, Smart, Jennifer I, Mendes, Rodrigo E, Pfaller, Michael A

“…Ceftobiprole medocaril is an advanced-generation cephalosporin prodrug that has qualified infectious disease product status granted by the US FDA and is…”
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Ceftobiprole Activity against Gram-Positive and -Negative Pathogens Collected from the United States in 2006 and 2016 by Pfaller, Michael A, Flamm, Robert K, Mendes, Rodrigo E, Streit, Jennifer M, Smart, Jennifer I, Hamed, Kamal A, Duncan, Leonard R, Sader, Helio S

“…Ceftobiprole is an advanced cephalosporin with potent activity against Gram-positive and Gram-negative bacteria that has been approved in many European and…”
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Ceftobiprole activity against Gram-positive and Gram-negative pathogens causing bone and joint infections in the United States from 2016 to 2020 by Duncan, Leonard R., Hamed, Kamal A., Smart, Jennifer I., Pfaller, Michael A., Flamm, Robert K., Mendes, Rodrigo E.

“…Bone and joint infections (BJIs) present significant treatment challenges. Ceftobiprole, a broad-spectrum cephalosporin with activity against…”
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Early improvement in severely ill patients with pneumonia treated with ceftobiprole: a retrospective analysis of two major trials by Scheeren, Thomas W L, Welte, Tobias, Saulay, Mikael, Engelhardt, Marc, Santerre-Henriksen, Anne, Hamed, Kamal

“…Patients with pneumonia who are elderly or severely ill are at a particularly high risk of mortality. This post hoc retrospective analysis of data from two…”
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Evaluation of Effectiveness and Safety of High-Dose Daptomycin: Results from Patients Included in the European Cubicin® Outcomes Registry and Experience by Seaton, R. Andrew, Menichetti, Francesco, Dalekos, Georgios, Beiras-Fernandez, Andres, Nacinovich, Francisco, Pathan, Rashidkhan, Hamed, Kamal

“…Introduction Daptomycin, a rapid concentration-dependent bactericidal antibiotic, is approved at a dose of 4 mg/kg/day for the treatment of complicated skin…”
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Ceftobiprole activity when tested against contemporary bacteria causing bloodstream infections in the United States (2016–2017) by Pfaller, Michael A., Flamm, Robert K., Duncan, Leonard R., Shortridge, Dee, Smart, Jennifer I., Hamed, Kamal A., Mendes, Rodrigo E., Sader, Helio S.

“…Ceftobiprole medocaril, the prodrug of ceftobiprole, is an advanced-generation cephalosporin that is approved in many European and non-European countries for…”
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An asymptotic model for solving mixed integral equation in some domains by Abdou, Mohamed Abdella, Awad, Hamed Kamal

“…In this paper, we discuss the solution of mixed integral equation with generalized potential function in position and the kernel of Volterra integral term in…”
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Machine learning and interactive GUI for concrete compressive strength prediction by Elshaarawy, Mohamed Kamel, Alsaadawi, Mostafa M., Hamed, Abdelrahman Kamal

“…Concrete compressive strength (CS) is a crucial performance parameter in concrete structure design. Reliable strength prediction reduces costs and time in…”
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Evaluation of Factors Predictive of Efficacy Among Patients With Complicated Urinary Tract Infection and/or Acute Pyelonephritis by Bhavnani, Sujata M, Hammel, Jeffrey P, Rubino, Christopher M, Talley, Angela K, Eckburg, Paul B, Liolios, Kathryn, Gupta, Vipul K, Ambrose, Paul G, Hamed, Kamal A, Melnick, David A

“…Abstract Background Antibiotic treatment for complicated urinary tract infections (cUTI)/acute pyelonephritis (AP) is often followed by recurrent bacteriuria…”
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Predicting discharge coefficient of triangular side orifice using ANN and GEP models by Mohamed Kamel Elshaarawy, Abdelrahman Kamal Hamed

“…ABSTRACTThis study utilized machine learning models to predict the discharge coefficient for a sharp-crested triangular side orifice (TSO). The chosen models…”
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Malaria Prevalence among Young Infants in Different Transmission Settings, Africa by Ceesay, Serign J, Koivogui, Lamine, Nahum, Alain, Taal, Makie Abdoulie, Okebe, Joseph, Affara, Muna, Kaman, Lama Eugène, Bohissou, Francis, Agbowai, Carine, Tolno, Benoit Gniouma, Amambua-Ngwa, Alfred, Bangoura, N Faly, Ahounou, Daniel, Muhammad, Abdul Khalie, Duparc, Stephan, Hamed, Kamal, Ubben, David, Bojang, Kalifa, Achan, Jane, D'Alessandro, Umberto

“…The prevalence and consequences of malaria among infants are not well characterized and may be underestimated. A better understanding of the risk for malaria…”
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Real-world daptomycin use across wide geographical regions: results from a pooled analysis of CORE and EU-CORE by Seaton, R Andrew, Gonzalez-Ruiz, Armando, Cleveland, Kerry O, Couch, Kimberly A, Pathan, Rashidkhan, Hamed, Kamal

“…Pooled data from two large registries, Cubicin(®) Outcomes Registry and Experience (CORE; USA) and European Cubicin(®) Outcomes Registry and Experience…”
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Administration of triclabendazole is safe and effective in controlling fascioliasis in an endemic community of the Bolivian Altiplano by Villegas, Fidel, Angles, René, Barrientos, René, Barrios, Gary, Valero, María Adela, Hamed, Kamal, Grueninger, Heiner, Ault, Steven K, Montresor, Antonio, Engels, Dirk, Mas-Coma, Santiago, Gabrielli, Albis Francesco

“…The Bolivian northern Altiplano is characterized by a high prevalence of Fasciola hepatica infection. In order to assess the feasibility, safety and efficacy…”
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