Search Results - "Hamda, Khaldoun Ben"

Effect of E670G Polymorphism in PCSK9 Gene on the Risk and Severity of Coronary Heart Disease and Ischemic Stroke in a Tunisian Cohort by Slimani, Afef, Harira, Yahia, Trabelsi, Imen, Jomaa, Walid, Maatouk, Faouzi, Hamda, Khaldoun Ben, Slimane, Mohamed Naceur

“…The association of E670G (rs505151) polymorphism in PCSK9 gene with an increased risk of coronary artery disease (CAD) and ischemic stroke (IS) was reported in…”
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Matrix metalloproteinase-1 and matrix metalloproteinase-12 gene polymorphisms and the risk of ischemic stroke in a Tunisian population by Chehaibi, Khouloud, Hrira, Mohamed Yahia, Nouira, Samir, Maatouk, Faouzi, Hamda, Khaldoun Ben, Slimane, Mohamed Naceur

“…Abstract Matrix metalloproteinases (MMPs) play an important role in early atherosclerosis, extracellular matrix remodeling, plaque rupture and myocardial…”
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Effect of mutations in LDLR and PCSK9 genes on phenotypic variability in Tunisian familial hypercholesterolemia patients by Slimani, Afef, Jelassi, Awatef, Jguirim, Imen, Najah, Mohamed, Rebhi, Lamia, Omezzine, Asma, Maatouk, Faouzi, Hamda, Khaldoun Ben, Kacem, Maha, Rabès, Jean-Pierre, Abifadel, Marianne, Boileau, Catherine, Rouis, Mustapha, Slimane, Mohamed Naceur, Varret, Mathilde

“…Highlights ► Phenotypic expression in Tunisian familial hypercholesterolemia varied widely. ► We identified a new putative loss of function mutation in PCSK9…”
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Cardiac iron overload detection using longitudinal strain in asymptomatic children with beta thalassemia major by Chamtouri, Ikram, Khalifa, Roueida, Besbes, Habib, jomaa, Walid, Abdallah, Wajih, Hamda, Khaldoun Ben, Chouchene, Chokri, Maatouk, Faouzi

“…Cardiomyopathy mediated by iron disposition in cardiomyocytes is a dreadful cause of morbidity and mortality in patients with beta thalassemia major (BTM)…”
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Increased Phospholipid Transfer Protein Activity Associated with the Impaired Cellular Cholesterol Efflux in Type 2 Diabetic Subjects with Coronary Artery Disease by Attia, Nebil, Nakbi, Amel, Smaoui, Maha, Chaaba, Raja, Moulin, Philippe, Hammami, Sonia, Hamda, Khaldoun Ben, Chanussot, Françoise, Hammami, Mohamed

“…Reverse cholesterol transport (RCT) is the pathway, by which the excess of cholesterol is removed from peripheral cells to the liver. An early step of RCT is…”
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Hsp70-2 gene polymorphism: susceptibility implication in Tunisian patients with coronary artery disease by Hrira, Mohamed Yahia, Chkioua, Latifa, Slimani, Afef, Chahed, Henda, Mosbah, Habib, Khaldoun, Hamda Ben, Ferchichi, Salima, Addad, Faouzi, Miled, Abdelhedi

“…Coronary artery disease (CAD) is a multifactorial disease where genetic and environmental factors interact in complex ways to cause the disease. Heat shock…”
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Plasma Metalloproteinase-12 and Tissue Inhibitor of Metalloproteinase-1 Levels and Presence, Severity, and Outcome of Coronary Artery Disease by Jguirim-Souissi, Imen, PhD, Jelassi, Awatef, PhD, Addad, Faouzi, MD, Hassine, Majed, MD, Najah, Mohamed, PhD, Hamda, Khaldoun Ben, MD, Maatouk, Faouzi, MD, Farhat, Mohamed Ben, MD, Bouslema, Ali, PhD, Rouis, Mustapha, PhD, Slimane, Mohamed Naceur, PhD

“…Several matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) have been implicated in the development and outcome of coronary…”
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TCTAP A-031 Predictors of Early Adverse Outcomes in Patients Presenting with ST-elevation Myocardial Infarction: Insights from a Tunisian 18-year Registry by Jomaa, Walid, Ben Abdeljelil, Ouday, Amdouni, Nesrine, Chamtouri, Ikram, Ben Hamda, Khaldoun, Maatouk, Faouzi

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TCTAP A-019 Early Outcomes in Patients Presenting for Acute ST-elevation Myocardial Infarction and Managed by Prehospital Thrombolysis: Results from a Tunisian Single Center Registry by Jomaa, Walid, Jnifene, Zouhair, Chamtouri, Ikram, El Hraiech, Aymen, Ben Hamda, Khaldoun, Maatouk, Faouzi

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TCTAP A-124 Prognostic Impact of Renal Function On-admission in Diabetic Patients Presenting for Acute ST-elevation Myocardial Infarction: Insights from a Tunisian Single Center Registry by Jomaa, Walid, Jnifene, Zouhair, Chamtouri, Ikram, El Hraiech, Aymen, Ben Hamda, Khaldoun, Maatouk, Faouzi

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TCTAP A-028 Prognostic Significance of Reperfusion Delays in Patients Presenting for ST-elevation Myocardial Infarction in the Tunisian Context by Jomaa, Walid, Ben Abdeljelil, Ouday, Ben Tekaya, Mohamed Ali, Chamtouri, Ikram, Ben Hamda, Khaldoun, Maatouk, Faouzi

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Clopidogrel utilization in patients with coronary artery disease and diabetes mellitus: should we determine CYP2C192 genotype? by Chouchene, Saoussen, Dabboubi, Rym, Raddaoui, Haythem, Abroug, Hela, Ben Hamda, Khaldoun, Hadj Fredj, Sondess, Abderrazak, Fatma, Gaaloul, Mayssa, Rezek, Marwa, Neffeti, Fadoua, Hellara, Ilhem, Sassi, Mouna, Khefacha, Linda, Sriha, Asma, Nouira, Semir, Najjar, Mohamed Fadhel, Maatouk, Faouzi, Messaoud, Taieb, Hassine, Mohsen

“…Purpose Clopidogrel non-responsiveness is multifactorial; several genetic and non-genetic factors may contribute to impaired platelet inhibition. The goal of…”
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Association of Left-Heart Dysfunction with Severe Exacerbation of Chronic Obstructive Pulmonary Disease: Diagnostic Performance of Cardiac Biomarkers by Abroug, Fekri, Ouanes-Besbes, Lamia, Nciri, Noureddine, Sellami, Noura, Addad, Faouzi, Hamda, Khaldoun Ben, Amor, Adel Ben, Najjar, Mohamed F, Knani, Jalel

“…Cardiac biomarkers are used to distinguish acute dyspnea due to left-heart dysfunction from that of pulmonary origin. However, they have not been assessed in…”
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Role of SCN5A coding and non-coding sequences in Brugada syndrome onset: What's behind the scenes? by Daimi, Houria, Khelil, Amel Haj, Neji, Ali, Ben Hamda, Khaldoun, Maaoui, Sabri, Aranega, Amelia, Be Chibani, Jemni, Franco, Diego

“…Brugada syndrome (BrS) is a rare inherited cardiac arrhythmia associated with a high risk of sudden cardiac death (SCD) due to ventricular fibrillation (VF)…”
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Prognostic value of hyperglycemia on-admission in diabetic versus non-diabetic patients presenting with ST-elevation myocardial infarction in Tunisia by Jomaa, Walid, El Mhamdi, Sana, Ben Ali, Imen, Azaiez, Mohamed A., El Hraiech, Aymen, Ben Hamda, Khaldoun, Maatouk, Faouzi

“…Hyperglycemia on-admission is a powerful predictor of adverse events in patients presenting for ST-elevation myocardial infarction (STEMI). In this study, we…”
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Mid-term subclinical myocardial injury detection in patients who recovered from COVID-19 according to pulmonary lesion severity by Chamtouri, Ikram, Kaddoussi, Rania, Abroug, Hela, Abdelaaly, Mabrouk, Lassoued, Taha, Fahem, Nesrine, Cheikh'Hmad, Saoussen, Ben Abdallah, Asma, Jomaa, Walid, Ben Hamda, Khaldoun, Maatouk, Faouzi

“…Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) may cause damage to the cardiovascular system during the acute phase of the infection…”
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Risk profile and in-hospital prognosis in elderly patients presenting for acute ST-elevation myocardial infarction in the Tunisian context by Jomaa, Walid, Hamdi, Sonia, Ben Ali, Imen, Azaiez, Mohamed A, El Hraiech, Aymen, Ben Hamda, Khaldoun, Maatouk, Faouzi

“…Abstract Objectives Little is known about the risk profile and in-hospital prognosis of elderly patients presenting for ST-elevation myocardial infarction…”
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Absence of Family History and Phenotype–Genotype Correlation in Pediatric Brugada Syndrome: More Burden to Bear in Clinical and Genetic Diagnosis by Daimi, Houria, Khelil, Amel Haj, Hamda, Khaldoun Ben, Aranega, Amelia, Chibani, Jemni B. E., Franco, Diego

“…Brugada syndrome (BrS) is an autosomal-dominant genetic cardiac disorder caused in 18–30 % of the cases by SCN5A gene mutations and manifested by an atypical…”
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PCSK9 polymorphism in a Tunisian cohort: Identification of a new allele, L8, and association of allele L10 with reduced coronary heart disease risk by Slimani, Afef, Hrira, Mohamed Yahia, Najah, Mohamed, Jomaa, Walid, Maatouk, Faouzi, Hamda, Khaldoun Ben, Abifadel, Marianne, Rabès, Jean-Pierre, Boileau, Catherine, Rouis, Mustapha, Slimane, Mohamed Naceur, Varret, Mathilde

“…The c.61_63dupCTG (L10) allele of rs72555377 polymorphism in PCSK9 has been reported to be associated with low-density lipoprotein-cholesterol (LDL-C) levels…”
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TNF-α −308G > A and IL-6 −174G > C polymorphisms in Tunisian patients with coronary artery disease by Ghazouani, Lakhdar, Hadj Khalifa, Sonia Ben, Abboud, Nesrine, Hamda, Khaldoun Ben, Khalfallah, Ali Ben, Brahim, Nsiri, Almawi, Wassim Youssef, Mahjoub, Touhami

“…Our aim was to evaluate the contribution of tumor necrosis factor (TNF)-α −308G > A and interleukin (IL)-6 −174G > C gene promoter variants to the presence of…”
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