Search Results - "Hamborg, Mette"
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Protein Antigen Adsorption to the DDA/TDB Liposomal Adjuvant: Effect on Protein Structure, Stability, and Liposome Physicochemical Characteristics
Published in Pharmaceutical research (01-01-2013)“…ABSTRACT Purpose Understanding the nature of adjuvant-antigen interactions is important for the future design of efficient and safe subunit vaccines, but…”
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Elucidating the mechanisms of protein antigen adsorption to the CAF/NAF liposomal vaccine adjuvant systems: Effect of charge, fluidity and antigen-to-lipid ratio
Published in Biochimica et biophysica acta (01-08-2014)“…The reverse vaccinology approach has recently resulted in the identification of promising protein antigens, which in combination with appropriate adjuvants can…”
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First-in-human use of a modular capsid virus-like vaccine platform: an open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2
Published in The Lancet. Microbe (01-03-2023)“…Capsid virus-like particles (cVLP) have proven safe and immunogenic and can be a versatile platform to counter pandemics. We aimed to clinically test a modular…”
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The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine
Published in PloS one (01-09-2015)“…The disease caused by Plasmodium falciparum (Pf) involves different clinical manifestations that, cumulatively, kill hundreds of thousands every year…”
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The physical stability of the recombinant tuberculosis fusion antigens h1 and h56
Published in Journal of pharmaceutical sciences (01-10-2013)“…The recombinant fusion proteins hybrid 1 [H1 (Ag85B-ESAT-6)] and hybrid 56 [H56 (Ag85B-ESAT-6-Rv2660c)] derived from Mycobacterium tuberculosis are promising…”
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Studies of the aggregation of RNase Sa
Published in Journal of pharmaceutical sciences (01-02-2014)“…Thirty-eight mutants of RNase Sa (ribonuclease from Streptomyces aureofaciens) were examined for their structure, thermal sensitivity, and tendency to…”
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The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine: e0135406
Published in PloS one (01-09-2015)“…The disease caused by Plasmodium falciparum (Pf) involves different clinical manifestations that, cumulatively, kill hundreds of thousands every year…”
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